Patents by Inventor Horst Ruther
Horst Ruther has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11130133Abstract: The invention relates to a migration device (100) having a sample chamber (102), a migration matrix (105) arranged in the sample chamber (102), and a fluid outlet (103). The migration device (100) also has a discharge structure (104), which is designed to discharge fluids from the sample chamber (102) to the fluid outlet (103). The invention also relates to methods for operating the migration device and to the use of a migration device for determining the migration ability of ameboidally mobile cells.Type: GrantFiled: August 9, 2016Date of Patent: September 28, 2021Assignee: MEON MEDICAL SOLUTIONS GMBH & CO. KGInventors: Herfried Huemer, Doris Zahrl, Horst Rüther
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Publication number: 20180229238Abstract: The invention relates to a migration device (100) having a sample chamber (102), a migration matrix (105) arranged in the sample chamber (102), and a fluid outlet (103). The migration device (100) also has a discharge structure (104), which is designed to discharge fluids from the sample chamber (102) to the fluid outlet (103). The invention also relates to methods for operating the migration device and to the use of a migration device for determining the migration ability of ameboidally mobile cells.Type: ApplicationFiled: August 9, 2016Publication date: August 16, 2018Applicant: MEON MEDICAL SOLUTIONS GMBH & CO. KGInventors: Herfried Huemer, Doris Zahrl, Horst Rüther
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Patent number: 7186384Abstract: The invention relates to a sample entry device for delivering medical samples, preferably blood samples, from diverse sample containers to an analyzer, wherein sample transfer between sample intake and measuring cells of the analyzer taking place via gas-tight sample lines. According to the invention a fixed intake needle is provided at the entry side of the analyzer, which includes an elastic intake element that is axially slideable on the intake needle and has a conical intake opening. In addition, a holding element is provided, which is axially slideable parallel to the intake needle and can be shifted relative to the intake element. In a first position the holding element exposes the intake element and in a second position places a conical opening above the intake element to accommodate a syringe.Type: GrantFiled: March 12, 2003Date of Patent: March 6, 2007Assignee: Roche Diagnostics CorporationInventors: Horst Rüther, Michael Kraker
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Publication number: 20030180193Abstract: The invention relates to a sample entry device for delivering medical samples, preferably blood samples, from diverse sample containers to an analyzer, wherein sample transfer between sample intake and measuring cells of the analyzer taking place via gas-tight sample lines. According to the invention a fixed intake needle is provided at the entry side of the analyzer, which includes an elastic intake element that is axially slideable on the intake needle and has a conical intake opening. In addition, a holding element is provided, which is axially slideable parallel to the intake needle and can be shifted relative to the intake element. In a first position the holding element exposes the intake element and in a second position places a conical opening above the intake element to accommodate a syringe.Type: ApplicationFiled: March 12, 2003Publication date: September 25, 2003Inventors: Horst Ruther, Michael Kraker
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Patent number: 6405872Abstract: In order to improve the shelflife of tonometered fluids containing at least one dissolved gas component and being packaged in a flexible container, a gas phase containing at least the dissolved gas component of the fluid is additionally introduced into the flexible container. The volume of the tonometered fluid and the volume of the gas phase together amounting to less than the maximum filling volume of the flexible container, which is collapsed when it is empty but unfolding when it is being filled.Type: GrantFiled: September 13, 2000Date of Patent: June 18, 2002Assignee: F. Hoffmann-La Roche AGInventors: Horst Rüther, Helmut List
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Patent number: 6099510Abstract: A device for withdrawing a liquid from a sealed glass ampoule includes a frame holding the sealed glass ampoule in upright or slightly inclined position, such that a tip of the ampoule points upwardly. An element is provided which will press or knock against the side of the tip or neck of the ampoule in order to break the tip of the ampoule in the region of the neck. The device further includes a withdrawing element which can be introduced into the glass ampoule in an area between the bottom of the ampoule and the surface of the liquid therein, and which includes a cannula for withdrawing the liquid.Type: GrantFiled: December 21, 1998Date of Patent: August 8, 2000Assignee: AVL Medical Instruments AGInventors: Horst Ruther, Helmut List, Gerald Kirchmayer
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Patent number: 6047719Abstract: In a gas mixing system for producing high-precision, continuous streams of mixed gas consisting of a plurality of individually metered gas components, with an individual gas line including a pressure reducing element and, if desired, a precision pressure regulator for each gas component, precision is further improved by providing that each gas line lead to a separate valve which is timed by electronic control means, the valves being connected at the input side via a jointly vented system of lines for pressure equalization, and communicating at the output side via a mixed gas line with a mixing chamber downstream thereof.Type: GrantFiled: December 22, 1998Date of Patent: April 11, 2000Assignee: AVL Medical Instruments AGInventors: Horst Ruther, Roland Raith
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Patent number: 5948366Abstract: In a glass ampoule for holding a drug, a calibration liquid or a quality control liquid, whose bottom is flat or recessed towards the interior of the ampoule, the bottom area is shaped and/or coated such that a predefined breaking site is provided, which can be mechanically destroyed with little use of force.Type: GrantFiled: December 30, 1997Date of Patent: September 7, 1999Assignee: AVL Medical INstruments AGInventor: Horst Ruther
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Patent number: 5628353Abstract: For the purpose of automatically drawing a liquid from a sealed glass ampoule the latter is held in a support in upright position with the ampoule bottom facing upwards, and the bottom is destroyed mechanically by inserting a withdrawing element. The liquid content of the ampoule is then sucked from a splinter-free zone of the glass ampoule.Type: GrantFiled: June 13, 1995Date of Patent: May 13, 1997Assignee: AVL Medical Instruments AGInventor: Horst Ruther
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Patent number: 5474276Abstract: In order to avoid dead volumes in a valve for control of a branch line departing from the main line in a valve chamber located in a valve housing, the valve chamber contains an elastomer part provided with a main channel and a branch channel departing from it, and the two ends of the main channel are sealingly connected with the main lines. The free end of the branch channel is sealingly connected with the branch line, and further that a valve lifter be provided in the valve housing, which acts on the branch channel in the branch-off area directly adjacent to the main channel of the elastomer part, thus reducing the cross-section of the branch channel, which is held in place by a counterpiece in the valve housing.Type: GrantFiled: August 4, 1994Date of Patent: December 12, 1995Assignee: AVL Medical Instruments AGInventors: Wolf-Dietrich Steinbock, Gunther Pucher, Horst Ruther, Helmut Zach
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Patent number: 5270008Abstract: An analyzing device, in particular for examining body fluids, with a measuring module, at least one gas feed tube for a calibrating gas, a moistening device for the calibrating gas as well as a washing water tube connectable to the measuring channel of the measuring module, is simplified and improved in that the moistening device for the calibrating gas is integrated in the washing water conduit through a water inlet and a water outlet. The calibrating gas can be led over the water surface in the moistening device and moistened in this way.Type: GrantFiled: April 30, 1992Date of Patent: December 14, 1993Assignee: AVL Medical Instruments AGInventor: Horst Ruther
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Patent number: 5160420Abstract: An analyzing apparatus for the purpose of analyzing samples of body fluids, comprising a sample feeding device and a measuring channel in which measuring probes are contained. In order to attain good reproducibility and uniform conditions of treatment of the samples the measuring channel is separated by means of a valve from a storage tank communicating with the sample feeding device.Type: GrantFiled: April 29, 1991Date of Patent: November 3, 1992Assignee: AVL Medical Instruments AGInventors: Hermann Marsoner, Horst Ruther
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Patent number: 5032362Abstract: An analyzing apparatus for the purpose of analyzing samples of body fluids, comprising a sample feeding device and a measuring channel in which measuring probes are contained. In order to attain good reproducibility and uniform conditions of treatment of the samples the measuring channel is separated by a valve from a storage tank communicating with the sample feeding device.Type: GrantFiled: June 14, 1988Date of Patent: July 16, 1991Assignee: AVL A.G.Inventors: Hermann Marsoner, Horst Ruther