Patents by Inventor Hosni M. Hassan

Hosni M. Hassan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED SALMONELLA SEROVAR TYPHIMURIUM STRAINS, COMPOSITIONS THEREOF, AND METHODS OF USE
    Publication number: 20210283234
    Abstract: Provided herein are engineered Salmonella enterica serovar Typhimurium strains and compositions, including vaccines, thereof. Also provided herein are methods of treating and/or preventing infection by at least Salmonella enterica serovar Typhimurium in a subject in need thereof by administering a vaccine provided herein.
    Type: Application
    Filed: July 28, 2017
    Publication date: September 16, 2021
    Inventors: HOSNI M. HASSAN, STEPHEN BRYAN TROXELL
  • Attenuated FNR deficient enterobacteria
    Patent number: 8435506
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: May 7, 2013
    Assignee: North Carolina State University
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans
  • ATTENUATED FNR DEFICIENT ENTEROBACTERIA
    Publication number: 20120128718
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Application
    Filed: December 15, 2011
    Publication date: May 24, 2012
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans
  • Attenuated FNR deficient enterobacteria
    Patent number: 8101168
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: January 24, 2012
    Assignee: North Carolina State University
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans
  • ATTENUATED FNR DEFICIENT ENTEROBACTERIA
    Publication number: 20100255036
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Application
    Filed: July 9, 2009
    Publication date: October 7, 2010
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans