Patents by Inventor Hotan MOJARRADI
Hotan MOJARRADI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230416469Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: ApplicationFiled: September 5, 2023Publication date: December 28, 2023Applicant: Galderma Holding SAInventors: Hotan MOJARRADI, Johan OLSSON, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loïc TOMAS
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Patent number: 11780970Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: GrantFiled: March 15, 2023Date of Patent: October 10, 2023Assignee: GALDERMA HOLDING S.A.Inventors: Hotan Mojarradi, Johan Olsson, Craig Harris, Jean-Guy Boiteau, Thibaut Gerfaud, Loïc Tomas
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Publication number: 20230212360Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: ApplicationFiled: March 15, 2023Publication date: July 6, 2023Applicant: Galderma Holding SAInventors: Hotan MOJARRADI, Johan OLSSON, Craig HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loïc TOMAS
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Patent number: 11643509Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: GrantFiled: November 29, 2022Date of Patent: May 9, 2023Assignee: Galderma Holding SAInventors: Hotan Mojarradi, Johan Olsson, Craig Steven Harris, Jean-Guy Boiteau, Thibaut Gerfaud, Loïc Tomas
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Publication number: 20230102832Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: ApplicationFiled: November 29, 2022Publication date: March 30, 2023Applicant: Galderma Holding SAInventors: Hotan MOJARRADI, Johan OLSSON, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loïc TOMAS
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Patent number: 11530301Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: GrantFiled: December 28, 2016Date of Patent: December 20, 2022Assignee: Galderma Holding SAInventors: Hotan Mojarradi, Johan Olsson, Craig Steven Harris, Jean-Guy Boiteau, Thibaut Gerfaud, Loïc Tomas
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Patent number: 11198765Abstract: A method of preparing a hydrogel product comprising crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include ester crosslinks formed as byproducts during the amide crosslinking; and ii) subjecting the crosslinked glycosaminoglycans to alkaline treatment to hydrolyze ester crosslinks formed as byproducts during the amide crosslinking.Type: GrantFiled: December 28, 2016Date of Patent: December 14, 2021Assignee: GALDERMA HOLDING SAInventors: Johan Olsson, Hotan Mojarradi
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Publication number: 20200140626Abstract: A method of preparing a hydrogel product comprising crosslinked glycosaminoglycan molecules, comprising the steps of: (a) providing a mixed solution of glycosaminoglycan molecules, a di- or multinucleophilic functional crosslinker, and a mononucleophilic functional graft chain; (b) activating carboxyl groups on the glycosaminoglycan molecules with a coupling agent to form activated glycosaminoglycan molecules; and (c) simultaneously crosslinking the activated glycosaminoglycan molecules and grafting the graft chain to the activated glycosaminoglycan molecules by reacting the nucleophiles with the activated carboxyl groups.Type: ApplicationFiled: December 27, 2019Publication date: May 7, 2020Inventors: Nord LARS, Hotan MOJARRADI, Johan OLSSON
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Publication number: 20190023812Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: ApplicationFiled: December 28, 2016Publication date: January 24, 2019Applicant: GALDERMA S.A.Inventors: Hotan MOJARRADI, Johan OLSSON, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loïc TOMAS
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Publication number: 20190023855Abstract: A method of preparing a hydrogel product comprising crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include ester crosslinks formed as byproducts during the amide crosslinking; and ii) subjecting the crosslinked glycosaminoglycans to alkaline treatment to hydrolyze ester crosslinks formed as byproducts during the amide crosslinking.Type: ApplicationFiled: December 28, 2016Publication date: January 24, 2019Applicant: GALDERMA S.A.Inventors: Johan OLSSON, Hotan MOJARRADI
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Patent number: 10131718Abstract: A hyaluronic acid product is comprising a cross-linked hyaluronic acid and one or more dextran molecules. The hyaluronic acid is cross-linked by ether bonds, and the one or more dextran molecules are covalently grafted to the cross-linked hyaluronic acid.Type: GrantFiled: May 29, 2015Date of Patent: November 20, 2018Assignee: GALDERMA S.A.Inventors: Anders Karlsson, Hotan Mojarradi
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Publication number: 20180244807Abstract: A hyaluronic acid product is comprising a cross-linked hyaluronic acid and one or more dextran molecules. The hyaluronic acid is cross-linked by ether bonds, and the one or more dextran molecules are covalently grafted to the cross-linked hyaluronic acid.Type: ApplicationFiled: May 29, 2015Publication date: August 30, 2018Applicant: GALDERMA S.A.Inventors: Anders KARLSSON, Hotan MOJARRADI
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Publication number: 20180155456Abstract: A process of preparing a cross-linked polysaccharide product including hyaluronic acid and dextran, the process including the steps of: (a) providing a hyaluronic acid and a dextran; (b) binding the dextran to the hyaluronic acid by ether bonds using a bi- or polyfunctional cross-linking agent, wherein the hyaluronic acid provided in step (a) is a cross-linked hyaluronic acid gel, and the dextran provided in step (a) is a non-cross-linked dextran; and wherein step (b) includes cross-linking the dextran to the hyaluronic acid by ether bonds using a bi- or polyfunctional cross-linking agent.Type: ApplicationFiled: May 29, 2015Publication date: June 7, 2018Applicant: GALDERMA S.A.Inventors: Anders KARLSSON, Hotan MOJARRADI, Elin SÄWÉN
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Publication number: 20170362347Abstract: A hydrogel product is comprising a chondroitin, molecule selected from the group consisting of chondroitin and chondroitin sulfate as the swellable polymer, wherein the chondroitin molecule is cross-linked into a network via its carboxyl groups. The hydrogel product can be prepared by a process comprising the steps of (a) providing chondroitin molecules; (b) activating the carboxyl groups on the chondroitin molecules with a triazine-based coupling reagent to form an activated, cross-linked chondroitin; and (c) cross-linking the activated chondroitin molecules via their carboxyl groups using a cross-linking agent. The hydrogel product is useful for treatment of soft tissue disorders.Type: ApplicationFiled: December 28, 2015Publication date: December 21, 2017Applicant: Galderma S.A.Inventors: Anders KARLSSON, Hotan MOJARRADI