Abstract: The present invention generally relates to a method for treating a demyelinating condition, in particular, by administering a combination comprising therapeutically effective amounts of a Rho-associated protein kinase (ROCK) inhibitor, a cyclin-dependent kinase (CDK) inhibitor, and a cyclic adenosine monophosphate (cAMP) activator to a subject in need thereof.

Abstract: The present invention generally relates to a method for generating induced oligodendrocyte-lineage cells (induced OLGs) and treatment using such cells. The induced OLGs are useful in cell therapy, in particular for demyelinating diseases.

Abstract: The present disclosure is drawn to methods and compositions directed at durable ink-jet inks. As such, an ink-jet ink can have a liquid vehicle, a colorant dispersed or dissolved in the liquid vehicle, a high Tg polymer having a Tg of at least 45.degree. C. dispersed in the liquid vehicle, and a near-infrared absorbing dye in the liquid vehicle. The ink can be formulated such that when printed on a substrate and irradiated with a near-infrared energy source, the near-infrared absorbing dye generates enough heat to uniformly melt the high Tg polymer, thereby enhancing the durability of ink-jet ink printed on the substrate.

Abstract: An inkjet printing composition comprises an aqueous liquid vehicle; at least one pigment having a concentration of about 1 to 5 wt %; and a latex polymer having a concentration of about 2.5 to 8 wt % and comprising a polymerized mixture of styrene, butyl acrylate, at least one of methacrylonitrile and acrylonitrile, methacrylic acid, and ethylene glycol dimethacrylate. An inkjet ink printing system comprises a vinyl medium; the at least one inkjet printing composition; and a heating device, wherein the system is configured such that upon applying heat from the heating device to the inkjet ink printed on the vinyl medium, the latex particles fuse, thereby forming a printed image with a film encapsulating at least a portion of the pigment on the vinyl medium. A method of forming a printed image of the latex polymer using the inkjet ink printing system is also provided.

Abstract: Polyphenylated phthalocyanine water-soluble dyes with near-infrared absorption comprise four isoindole units linked together in a large ring to form a phthalocyanine macrocycle, with either four anthracenyl groups or four naphthacenyl groups each linked to an isoindole, and a metal atom optionally complexed to the phthalocyanine macrocycle.

Abstract: Encapsulated dyes for non-water based printing applications comprise a plurality of dye molecules embedded in a polymeric matrix. A process for making the encapsulated dyes and an electrophotographic ink including an ink vehicle and the encapsulated dyes are also provided.

Abstract: The present disclosure is drawn to methods and compositions directed at durable ink-jet inks. As such, an ink-jet ink can comprise a liquid vehicle, a colorant dispersed or dissolved in the liquid vehicle, a high Tg polymer having a Tg of at least 45° C. dispersed in the liquid vehicle, and a near-infrared absorbing dye in the liquid vehicle. The ink can be formulated such that when printed on a substrate and irradiated with a near-infrared energy source, the near-infrared absorbing dye generates enough heat to uniformly melt the high Tg polymer, thereby enhancing the durability of ink-jet ink printed on the substrate.

Abstract: An inkjet printing composition comprises an aqueous liquid vehicle; at least one pigment having a concentration of about 1 to 5 wt %; and a latex polymer having a concentration of about 2.5 to 8 wt % and comprising a polymerized mixture of styrene, butyl acrylate, at least one of methacrylonitrile and acrylonitrile, methacrylic acid, and ethylene glycol dimethacrylate. An inkjet ink printing system comprises a vinyl medium; the at least one inkjet printing composition; and a heating device, wherein the system is configured such that upon applying heat from the heating device to the inkjet ink printed on the vinyl medium, the latex particles fuse, thereby forming a printed image with a film encapsulating at least a portion of the pigment on the vinyl medium. A method of forming a printed image of the latex polymer using the inkjet ink printing system is also provided.

Abstract: Polyphenylated phthalocyanine water-soluble dyes with near-infrared absorption comprise four isoindole units linked together in a large ring to form a phthalocyanine macrocycle, with either four anthracenyl groups or four naphthacenyl groups each linked to an isoindole, and a metal atom optionally complexed to the phthalocyanine macrocycle.

Abstract: Crystal growth performed in situ facilitates interconnection of prefabricated nano-structures. The nano-structures are immersed in a growth solution having a controllable saturation condition. Changing the saturation condition of the solution modifies a size of the immersed nanowires. The solution includes a solute of a nano-structure precursor material. The saturation condition is changed to one or both etch material from a surface of the nano-structures and initiate crystal growth on the nano-structure surface. A nano-structure interconnection system includes the growth solution and equipment to deposit the prefabricated nano-structures on a substrate. An interconnected structure includes a plurality of nano-structures disposed on a substrate in a cluster and a liquid phase-grown crystal lattice on surfaces of the nano-structures to form physical interconnections between the plurality. An ink formulation includes the plurality of nano-structures suspended in the growth solution.

Abstract: A self-aligning nanowire includes a nanowire portion and an aligning member attached to the nanowire portion. The aligning member interacts with another aligning member on an adjacent self-aligning nanowire to align the nanowires together. A method of aligning nanowires includes providing a plurality of the self-aligning nanowires, suspending the plurality in a carrier solution, and depositing the suspended plurality on a substrate. An ink formulation includes the plurality of suspended self-aligning nanowires in the carrier solution. A method of producing the self-aligning nanowire includes providing and associating the nanowire portion and the aligning member such that the nanowire produced is self-aligning with another nanowire.

Abstract: Crystal growth performed in situ facilitates interconnection of prefabricated nano-structures. The nano-structures are immersed in a growth solution having a controllable saturation condition. Changing the saturation condition of the solution modifies a size of the immersed nanowires. The solution includes a solute of a nano-structure precursor material. The saturation condition is changed to one or both etch material from a surface of the nano-structures and initiate crystal growth on the nano-structure surface. A nano-structure interconnection system includes the growth solution and equipment to deposit the prefabricated nano-structures on a substrate. An interconnected structure includes a plurality of nano-structures disposed on a substrate in a cluster and a liquid phase-grown crystal lattice on surfaces of the nano-structures to form physical interconnections between the plurality. An ink formulation includes the plurality of nano-structures suspended in the growth solution.