Patents by Inventor Houjian Cao

Houjian Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911433
    Abstract: A preparation method of non-ester tea polyphenols rich in EGC. Includes leaching wall-broken crushed tea leaves using endogenous hydrolytic enzymes contained in the tea leaves; refining the leached solution after filtration and concentration and purifying it by mobile leaching-water washing; concentrating and drying the purified product to obtain a non-ester tea polyphenols product rich in EGC, wherein the content of tea polyphenols is 90-99.5%, the content of EGC is greater than 80%, and the content of ester catechins EGCG+ECG is less than 10%.
    Type: Grant
    Filed: January 17, 2022
    Date of Patent: February 27, 2024
    Assignee: JIANGSU DEHE BIOTECHNOLOGY CO., LTD.
    Inventors: Xueyin Ren, Jianhong Liu, Houjian Cao, Pingnan Pu, Dehe Liu
  • Publication number: 20230241151
    Abstract: The present invention relates to a preparation method of non-ester tea polyphenols rich in EGC. Wall-broken crushed tea leaves are subjected to leaching using endogenous hydrolytic enzymes contained in the tea leaves. The leached solution after filtration and concentration is subjected to refining and purification by mobile leaching-water washing. The purified product is subjected to concentration and drying to obtain a non-ester tea polyphenols product rich in EGC, wherein the content of tea polyphenols is 90-99.5%, the content of EGC is greater than 80%, and the content of ester catechins EGCG+ECG is less than 10%. According to the preparation method of the non-ester tea polyphenols rich in EGC of the present invention, it does not add any exogenous hydrolytic enzyme, so as to avoid the contamination to the product by the exogenous hydrolytic enzyme. Meanwhile, the content of EGC is high, the production process is simplified, and the yield of the product is high, which is conducive to industrial production.
    Type: Application
    Filed: January 17, 2022
    Publication date: August 3, 2023
    Applicant: JIANGSU DEHE BIOTECHNOLOGY CO., LTD.
    Inventors: Xueyin REN, Jianhong LIU, Houjian CAO, Pingnan PU, Dehe LIU
  • Patent number: 8282970
    Abstract: A process for producing purified theaflavin extract is provided which comprises combining an organic solvent with tea leaves, extracting polyphenols from the tea leaves to produce an organic stock substrate solution; producing a second batch of tea leaves; grinding the second batch of tea leaves to produce stock fermentation enzyme; combining the stock substrate solution with the stock fermentation enzyme to produce a fermentation mixture; fermentation of the mixture to produce theaflavins; and, separating the theaflavins from the fermentation mixture to produce purified theaflavin extract. Oral dosage forms are provided which comprise an effective amount of the purified theaflavin extract. Methods of treatment of human physiological disorders are provided which comprise administering an oral dosage form.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: October 9, 2012
    Assignee: Jiahgsu Dehe Bio-Tech Co., Ltd
    Inventors: Xiaowei Shi, Xueyin Ren, Jianhong Liu, Houjian Cao, Wenhao Ren, Yizhou Cao
  • Publication number: 20110082196
    Abstract: A process for producing purified theaflavin extract is provided which comprises combining an organic solvent with tea leaves, extracting polyphenols from the tea leaves to produce an organic stock substrate solution; producing a second batch of tea leaves; grinding the second batch of tea leaves to produce stock fermentation enzyme; combining the stock substrate solution with the stock fermentation enzyme to produce a fermentation mixture; fermentation of the mixture to produce theaflavins; and, separating the theaflavins from the fermentation mixture to produce purified theaflavin extract. Oral dosage forms are provided which comprise an effective amount of the purified theaflavin extract. Methods of treatment of human physiological disorders are provided which comprise administering an oral dosage form.
    Type: Application
    Filed: October 7, 2009
    Publication date: April 7, 2011
    Applicant: Jiangsu Dehe Bio-Tech Co., Ltd.
    Inventors: Xiaowei SHI, Xueyin REN, Jianhong LIU, Houjian CAO, Wenhao REN, Yizhou CAO