Abstract: A method of preparing layered hydrotalcite-like PVC heat stabilizer from vermiculite is disclosed, including the following steps. Vermiculite is pretreated to prepare nano scale vermiculite flakes. Fluoride, ammonia and water are added, and layered powder layered hydrotalcite-like compound and silica product are prepared through a series of reactions such as ultrasonic dispersion, which realizes the preparation of vermiculite functional products, and is applied to PVC products to improve the heat stability of PVC. The disclosure can directly prepare vermiculite base layered powder products, has the function of stripping layered vermiculite, and has the advantages of low reaction temperature and low energy consumption. In addition, the treatment agent fluoride can be recycled and reused, which is suitable for industrial production.