Patents by Inventor Howard A. Newman

Howard A. Newman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • .alpha.-[5-methyl-2-(pyridinyl)-1H-imidazol-4-yl]substituted-1-p iperazineethanols useful for treating hypertension
    Patent number: 4732895
    Abstract: This disclosure describes novel substituted .alpha.-[5-methyl-2-pyridyl-1H-imidazol-4-yl]-1-piperazineethanols which possess hypotensive activity.
    Type: Grant
    Filed: May 2, 1986
    Date of Patent: March 22, 1988
    Assignee: American Cyanamid Company
    Inventors: Corris M. Hofmann, Howard Newman, Andrew S. Tomcufcik
  • 10,10-dihydro-10-[(substituted-carbonyl)imino]-10-ph enyl-10H-phenoxaphosphines compositions containing same and therapeutic methods of use
    Patent number: 4689324
    Abstract: Novel 10,10-Dihydro-10-[(substituted carbonyl)imino]-10-phenyl-10H-phenoxaphines of the formula: ##STR1## wherein A is selected from the group consisting of hydrogen and COOR.sub.1, where, when A is hydrogen the compound is in the form of a water soluble salt HnX, where n is an integer 1 or 2 and X is selected from the group consisting of sulfate, trefluoroacetate, bromide and chloride and R.sub.1 is selected from the group consisting of straight or branched chain alkyl(C.sub.1 -C.sub.4), alkenyl(C.sub.2 -C.sub.4), alkynyl(C.sub.2 -C.sub.4), cycloalkyl(C.sub.3 -C.sub.6), cycloalkyl(C.sub.3 -C.sub.6)methyl, benzyl, pyridylmethyl or which tetrahydro-3-furanyl; methods for using these compounds for effecting diuresis, treating hypertension and edema and lowering plasma renin activity in mammals; pharmaceutical compositions of matter containing these compounds and processes for their preparation.
    Type: Grant
    Filed: March 5, 1986
    Date of Patent: August 25, 1987
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, Joseph W. Marsico, Nancy H. Eudy, Howard Newman
  • Novel heterocyclic anthracycline compounds
    Patent number: 4259476
    Abstract: Novel heterocyclic anthracycline compounds having antitumor activity against murine P388 leukemia in mice.
    Type: Grant
    Filed: April 2, 1979
    Date of Patent: March 31, 1981
    Inventors: Andrew S. Kende, Howard Newman
  • Substituted 1,2,4-triazole carboxamide
    Patent number: 4007198
    Abstract: This disclosure describes mixtures of novel sulfonyl-substituted 1,2,4-triazole-3-carboxamides which possess antiviral activity.
    Type: Grant
    Filed: May 1, 1975
    Date of Patent: February 8, 1977
    Assignee: American Cyanamid Company
    Inventor: Howard Newman
  • Substituted 1,2,4-triazole carboxamides
    Patent number: 4006159
    Abstract: This disclosure describes mixtures of novel acyl-substituted 1,2,4-triazole-3-carboxamides which possess antiviral activity.
    Type: Grant
    Filed: March 14, 1975
    Date of Patent: February 1, 1977
    Assignee: American Cyanamid Company
    Inventor: Howard Newman