Patents by Inventor Howard A. Whaley

Howard A. Whaley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotic nodusmicins
    Patent number: 4588817
    Abstract: Novel antibacterially-active esters of antibiotic nodusmicin. Activity is demonstrated against Staphylococcus aureus, Streptococcus pyogenes, and Sarcina lutea. Thus, these esters can be used in various known environments, using well-known procedures, to eradicate or control susceptible microbes.
    Type: Grant
    Filed: June 4, 1984
    Date of Patent: May 13, 1986
    Assignee: The Upjohn Company
    Inventors: Barney J. Magerlein, Howard A. Whaley
  • Antibiotic nodusmicin derivatives
    Patent number: 4461903
    Abstract: Novel antibacterially-active esters of antibiotic nodusmicin. Activity is demonstrated against Staphylococcus aureus, Streptococcus pyogenes, and Sarcina lutea. Thus, these esters can be used in various known environments, using well-known procedures, to eradicate or control susceptible microbes.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: July 24, 1984
    Assignee: The Upjohn Company
    Inventors: Barney J. Magerlein, Howard A. Whaley
  • Biologically pure culture of Streptomyces microspinus NRRL 12524 capable of producing antibiotic U-64,815
    Patent number: 4454228
    Abstract: Novel antibiotic U-64,815 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces microspinus, NRRL 12524. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus. It is also active against Haemophilus influenzae. Thus, antibiotic U-64,815 can be used in various environments to eradicate or control such bacteria.
    Type: Grant
    Filed: September 29, 1982
    Date of Patent: June 12, 1984
    Assignee: The Upjohn Company
    Inventors: Howard A. Whaley, William C. Snyder, John C. Greenfield, John H. Coats
  • Composition of matter and process
    Patent number: 4427776
    Abstract: Novel antibiotic U-64,815 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces microspinus, NRRL 12524. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus. It is also active against Haemophilus influenzae. Thus, antibiotic U-64,815 can be used in various environments to eradicate or control such bacteria.
    Type: Grant
    Filed: September 21, 1981
    Date of Patent: January 24, 1984
    Assignee: The Upjohn Company
    Inventors: Howard A. Whaley, William C. Snyder, John C. Greenfield, John H. Coats
  • Esters of antibiotic nodusmicin
    Patent number: 4363922
    Abstract: Novel antibacterially-active esters of antibiotic nodusmicin. Activity is demonstrated against Staphylococcus aureus, Streptococcus pyogenes, and Sarcina lutea. Thus, these esters can be used in various known environments, using well-known procedures, to eradicate or control susceptible microbes.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: December 14, 1982
    Assignee: The Upjohn Company
    Inventors: Barney J. Magerlein, Howard A. Whaley
  • Antibiotic nodusmicin derivatives
    Patent number: 4360683
    Abstract: Novel antibacterially-active esters of antibiotic nodusmicin. Activity is demonstrated against Staphylococcus aureus, Streptococcus pyogenes, and Sarcina lutea. Thus, these esters can be used in various known environments, using well-known procedures, to eradicate or control susceptible microbes.
    Type: Grant
    Filed: August 6, 1980
    Date of Patent: November 23, 1982
    Assignee: The Upjohn Company
    Inventors: Barney J. Magerlein, Howard A. Whaley
  • Antibiotic composition of matter
    Patent number: 4351769
    Abstract: Novel antibiotic U-61,732 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Saccharopolyspora hirsuta strain 367, NRRL 12045. This antibiotic is active against gram-positive bacteria, for example, Staphylococcus aureus. Also disclosed are the 11-acyl esters of U-61,732. Thus, these compounds can be used in various environments to eradicate or control such bacteria.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: September 28, 1982
    Assignee: The Upjohn Company
    Inventors: Howard A. Whaley, John H. Coats
  • Saccharopolyspora culture
    Patent number: 4321329
    Abstract: A process for preparing the antibiotic U-59,760. The process is a microbiological process using a biologically pure culture of the novel microbe Saccharopolyspora hirsuta strain 367, NRRL 12045. The antibiotic produced by the process is active against various microorganisms, for example, Staphylococcus aureus, Streptococcus pyogenes, and Klebsiella pneumoniae. Thus, antibiotic U-59,760 can be used in various environments to eradicate or control such bacteria.
    Type: Grant
    Filed: October 6, 1980
    Date of Patent: March 23, 1982
    Assignee: The Upjohn Company
    Inventors: Howard A. Whaley, John H. Coats
  • Process for producing antibiotic using saccharopolyspora
    Patent number: 4293651
    Abstract: A process for preparing the antibiotic U-59,760. The process is a microbiological process using a biologically pure culture of the novel microbe Saccharopolyspora hirsuta strain 367, NRRL 12045. The antibiotic produced by the process is active against various microorganisms, for example, Staphylococcus aureus, Streptococcus pyogenes, and Klebsiella pneumoniae. Thus, antibiotic U-59,760 can be used in various environments to eradicate or control such bacteria.
    Type: Grant
    Filed: October 2, 1979
    Date of Patent: October 6, 1981
    Assignee: The Upjohn Company
    Inventors: Howard A. Whaley, John H. Coats
  • Antibiotic and fermentation process of preparing
    Patent number: 4251511
    Abstract: Novel antibiotic U-59,761 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Saccharopolyspora hirsuta strain 367, NRRL 12045. This antibiotic is active against various microorganisms, for example, Staphylococcus aureus, Streptococcus pyogenes, Sarcina lutea, Klebsiella pneumoniae, Mycobacterium avium, and Bacteroides fragilis. Thus, antibiotic U-59,761 can be used in various environments to eradicate or control such bacteria.
    Type: Grant
    Filed: October 2, 1979
    Date of Patent: February 17, 1981
    Assignee: The Upjohn Company
    Inventors: Howard A. Whaley, John H. Coats
  • Antibiotic U-47,929 and its preparation
    Patent number: 3993748
    Abstract: New antibiotic U-47,929 produced by the controlled fermentation of the new microorganism Streptomyces ficellus Dietz, sp. n., NRRL 8067. This antibiotic and its acid-addition salts are active against Gram-positive bacteria. Accordingly, they can be used in various environments to eradicate or control such bacteria.
    Type: Grant
    Filed: January 20, 1975
    Date of Patent: November 23, 1976
    Assignee: The Upjohn Company
    Inventors: Alexander D. Argoudelis, Fritz Reusser, Howard A. Whaley