Abstract: The present subject matter provides, inter alia, compositions and methods comprising inactivated, non-viable, or dead Bacillus coagulans bacteria such as whole dead bacterial spores and/or cells and/or particles that comprise inactivated, non-viable, or dead Bacillus coagulans bacteria. Compositions and methods comprising Bacillus coagulans peptidoglycan and/or lipoteichoic acid are also provided.

Abstract: A personal transport vehicle is provided, which includes a front wheel assembly having a front rim and a front tire seated on the front rim, and a rear wheel assembly having a rear rim and a rear tire seated on the rear rim. The vehicle also includes a motor disposed within the rear rim of the rear wheel assembly and coupled to a mount of the rear rim, where the motor is configured to rotate the rear tire to cause movement of the personal transport vehicle. The vehicle further includes a frame coupled to the front wheel assembly and to the motor disposed within the rear wheel assembly, and a steering arm coupled to the front wheel assembly within the front rim for controlling movement of the front tire for steering the personal transport vehicle.

Abstract: A pottery wheel with an improved throwing arm that pushes the clay towards the center of the spinning plate, in an arc shaped motion, defined by four directions of motion, with the throwing arm providing an inward force towards the direction of rotation and towards the axis of rotation, that also allows for micro-adjustments to be easily made, is disclosed. Various tool accessories can then be used to open the pottery and form the pottery. The embodiments of the present invention are suitable for use by children, individuals unskilled in the art of pottery, and individuals lacking fine motor skills due to the assistance provided by the features of present embodiments, including an improved throwing arm removably attached to the housing. Embodiments of the present invention also include numerous attachments designed to work in tandem with the improved pottery wheel and throwing arm assembly.

Abstract: The present invention provides in one aspect azabicyclo and diazepine derivatives useful as modulators of muscarinic receptors. In another aspect, the present invention provides pharmaceutical compositions for treating ocular diseases, the compositions comprising at least one muscarinic receptor modulator.

Abstract: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.

Abstract: Disclosed is a magnetic housing assembly which may have a housing body, a first capping structure; a second capping structure; a water-tight chamber defined by the first capping structure and the second capping structure; a ratcheting face; a magnet enclosed within the water-tight chamber; at least one ridge on the perimeter of the housing body, where the magnet can flip to reverse polarity within the water-tight chamber, where the ratcheting face is configured to allow adjustment of the assembly when connected with another structure also having a ratcheting face. Also disclosed is a system including a structure configured to house the plurality of magnetic housing assemblies while exposing a surface of the magnetic housing assemblies.

Abstract: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.

Abstract: A personal transport vehicle is provided, which includes a front wheel assembly having a front rim and a front tire seated on the front rim, and a rear wheel assembly having a rear rim and a rear tire seated on the rear rim. The vehicle also includes a motor disposed within the rear rim of the rear wheel assembly and coupled to a mount of the rear rim, where the motor is configured to rotate the rear tire to cause movement of the personal transport vehicle. The vehicle further includes a frame coupled to the front wheel assembly and to the motor disposed within the rear wheel assembly, and a steering arm coupled to the front wheel assembly within the front rim for controlling movement of the front tire for steering the personal transport vehicle.

Abstract: The present invention provides in one aspect azabicyclo and diazepine derivatives useful as modulators of muscarinic receptors. In another aspect, the present invention provides pharmaceutical compositions for treating ocular diseases, the compositions comprising at least one muscarinic receptor modulator.

Abstract: Polymeric eye inserts are provided that may be dissolvable when placed in the cul-de-sac of the eye. These inserts may contain one or more mucoadhesive polymers polymers, a biodegradable polymer as well as softener/plasticizer so that, when inserted into the eye, they may absorb tears, and dissolve and slowly release lubricant into the tear film to lubricate and protect the ocular surface for an extended duration of time. The biodegradable polymer containing eye insert may increase dissolution time on the ocular surface for longer lasting relief, may reduce dosing frequency and patient burden typically associated with topical drop usage. These polymeric eye inserts also may include one or more pharmaceutically active agents.

Abstract: The present invention is directed to a lipid-based ophthalmic emulsion. The emulsion has an increased amount of a mucoadhesive galactomannan polymer that promotes a long-lasting protection against desiccation and moisture retention.

Abstract: A personal transport vehicle is provided capable of staying upright without the need for a stand by incorporating tires having an advantageous design combined with an overall lowered center of gravity. The personal transport vehicle further incorporates a hub and steering assembly configured within the front wheel of the vehicle, as well as a bake and propulsion means configured within the rear wheel of the vehicle. Finally, the personal transport vehicle is capable of being folded into a compact configuration, lending itself to ease of shipment, storage and transport.

Abstract: The present invention relates to artificial tear compositions and ophthalmic compositions suitable for drug delivery. In one embodiment of the present invention, the compositions comprise a galactomannan polymer such as guar or hydroxypropyl guar, hyaluronic acid, and a cis-diol such as sorbitol. In a preferred embodiment, the to compositions also comprise a borate compound.

Abstract: The present invention is directed to a lipid-based ophthalmic emulsion. The emulsion has an increased amount of a mucoadhesive galactomannan polymer that promotes a long-lasting protection against desiccation and moisture retention.

Abstract: A personal transport vehicle capable of staying upright without the need for a stand by incorporating tires having an advantageous design combined with an overall lowered center of gravity. The personal transport vehicle further incorporating a hub and steering assembly configured within the front wheel of the vehicle, as well as a brake and propulsion means configured within the rear wheel of the vehicle. Finally, the personal transport vehicle is capable of being folded into a compact configuration, lending itself to ease of shipment, storage and transport.

Abstract: A personal transport vehicle capable of staying upright without the need for a stand by incorporating tires having an advantageous design combined with an overall lowered center of gravity. The personal transport vehicle further incorporating a hub and steering assembly configured within the front wheel of the vehicle, as well as a brake and propulsion means configured within the rear wheel of the vehicle. Finally, the personal transport vehicle is capable of being folded into a compact configuration, lending itself to ease of shipment, storage and transport.

Abstract: The present invention relates to artificial tear compositions and ophthalmic compositions suitable for drug delivery. In one embodiment of the present invention, the compositions comprise a galactomannan polymer such as guar or hydroxypropyl guar, hyaluronic acid, and a cis-diol such as sorbitol. In a preferred embodiment, the compositions also comprise a borate compound.

Abstract: Polymeric eye inserts are provided that may be dissolvable when placed in the cul-de-sac of the eye. These inserts may contain one or more polymers as well as a softener/plasticizer so that, when inserted into the eye, they may absorb tears, and dissolve and slowly release lubricant into the tear film to lubricate and protect the ocular surface for an extended duration of time. Increased retention time on the ocular surface for longer lasting relief may reduce dosing frequency and patient burden typically associated with topical drop usage. These polymeric eye inserts also may include one or more pharmaceutically active agents.

Abstract: A personal transport vehicle capable of staying upright without the need for a stand by incorporating tires having an advantageous design combined with an overall lowered center of gravity. The personal transport vehicle further incorporating a hub and steering assembly configured within the front wheel of the vehicle, as well as a brake and propulsion means configured within the rear wheel of the vehicle. Finally, the personal transport vehicle is capable of being folded into a compact configuration, lending itself to ease of shipment, storage and transport.