Abstract: Compositions and methods for modulating nucleotide sequence expression, particularly for modulating gene expression in plants, are provided. The compositions comprise precursor RNA constructs for the expression of an RNA precursor. The precursor RNA construct comprises a promoter that is expressed in a plant cell driving the expression of a precursor RNA having a microRNA. The miRNA is complementary or partially complementary to a portion of a target gene or nucleotide sequence and function to modulate expression of the target sequence or gene. In this manner, the RNA precursor construct can be designed to modulate expression of any nucleotide sequence of interest, either an endogenous plant gene or alternatively a transgene. Transformed plants, tissues, cells and seeds are also provided.

Abstract: Disclosed herein are terpolymers that can function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymers adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive terpolymer adhered to a surface thereof. The pressure-sensitive adhesive terpolymer can promote adhesion of the implant device to a location in a subject.

Abstract: Disclosed herein are terpolymers and blends prepared from polyester terpolymers that can function as pressure-sensitive adhesives. The disclosed articles can comprise the terpolymer and terpolymer blends coated to a conformable backing member. The terpolymer and terpolymer blends can further comprise a bioactive agent.

Abstract: Described herein are terpolymer compositions, kits comprising the compositions, implant devices comprising the compositions, and methods of making and using same, including point of use methods.

Abstract: Disclosed are terpolymer compositions of lactide, glycolide, and caprolactone and methods of making such polymers with an initiator. Methods of using the terpolymers as a drug delivery platform are also disclosed.

Abstract: Disclosed herein are blends prepared from polyester terpolymers that function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymer blends adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive blend adhered to a surface thereof. The pressure-sensitive adhesive blend can promote adhesion of the implant device to a location in a subject.

Abstract: Disclosed herein are blends prepared from polyester terpolymers that function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymer blends adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive blend adhered to a surface thereof. The pressure-sensitive adhesive blend can promote adhesion of the implant device to a location in a subject.

Abstract: Compositions and methods for modulating nucleotide sequence expression, particularly for modulating gene expression in plants, are provided. The compositions comprise precursor RNA constructs for the expression of an RNA precursor. The precursor RNA construct comprises a promoter that is expressed in a plant cell driving the expression of a precursor RNA having a microRNA. The miRNA is complementary or partially complementary to a portion of a target gene or nucleotide sequence and function to modulate expression of the target sequence or gene. In this manner, the RNA precursor construct can be designed to modulate expression of any nucleotide sequence of interest, either an endogenous plant gene or alternatively a transgene. Transformed plants, tissues, cells and seeds are also provided.

Abstract: Disclosed herein are terpolymers that can function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymers adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive terpolymer adhered to a surface thereof. The pressure-sensitive adhesive terpolymer can promote adhesion of the implant device to a location in a subject.

Abstract: Disclosed herein are terpolymers and blends prepared from polyester terpolymers that can function as pressure-sensitive adhesives. The disclosed articles can comprise the terpolymer and terpolymer blends coated to a conformable backing member. The terpolymer and terpolymer blends can further comprise a bioactive agent.

Abstract: Disclosed herein are blends prepared from polyester terpolymers that function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymer blends adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive blend adhered to a surface thereof. The pressure-sensitive adhesive blend can promote adhesion of the implant device to a location in a subject.

Abstract: Disclosed are terpolymer compositions of lactide, glycolide, and caprolactone and methods of making such polymers with an initiator. Methods of using the terpolymers as a drug delivery platform are also disclosed.

Abstract: Described herein are terpolymer compositions, kits comprising the compositions, implant devices comprising the compositions, and methods of making and using same, including point of use methods.

Abstract: Disclosed are terpolymer compositions of lactide, glycolide, and caprolactone and methods of making such polymers with an initiator. Methods of using the terpolymers as a drug delivery platform are also disclosed.

Abstract: A hitch lock for inhibiting the theft of a trailer. The hitch lock includes a base member having a base plate. The base plate is designed for abutting a bottom of the trailer hitch. The base member has a rod portion. The rod portion is coupled to the base plate whereby the rod portion extends through an aperture of the trailer hitch. A top plate has a receiving bore. The receiving bore slidably receives the rod portion of the base member. The top plate is designed for abutting a top of the trailer hitch when the receiving bore receives the rod portion of the base member and the base plate abuts the bottom of the trailer hitch. A locking member is selectively couplable to the rod portion of the base member for securing the top plate to the base member.

Abstract: A new door threshold/weatherstripping device is disclosed that uses rollers, installed either in a door to contact a threshold surface, or in the threshold to contact the door. The rollers are supported by bearings that permit the rollers to turn freely as the door is opened or closed. The bearings are mounted in housings that have adjustable, spring loaded pistons. These pistons permit the spacing of rollers with respect to the threshold (or door) to be adjusted to ensure a tight seal. In the embodiment that utilizes a threshold mounted roller, a gripper pad is used to prevent the roller from turning when a person steps on it. This prevent possible slipping injuries. Both embodiments have brushes mounded adjacent to the rollers to clean them of dirt, snow and water.