Patents by Inventor Howard Cheskin

Howard Cheskin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulation comprising a drug of low water solubility and method of use thereof
    Publication number: 20070104780
    Abstract: A pharmaceutical composition comprises a drug-carrier system having a small-molecule drug of low water solubility, e.g. N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N?-(2-fluoro-5-methylphenyl)urea (ABT-869), and (+)-1-(5-tert-butyl-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102), in solution in a substantially non-aqueous carrier that comprises at least one phospholipid and a pharmaceutically acceptable solubilizing agent. The drug-carrier system, when mixed with an aqueous phase, typically forms a non-gelling, substantially non-transparent liquid dispersion. The composition is suitable for administration by a suitable route, e.g. orally, to a subject in need thereof.
    Type: Application
    Filed: October 24, 2006
    Publication date: May 10, 2007
    Inventors: John Lipari, Didier Lefebvre, Tzuchi Ju, Kennan Marsh, Geoff Zhang, Jayanthy Jayanth, Chetan Pujara, Howard Cheskin, Vitomir Vucenovic, Ping Tong
  • Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
    Patent number: 5807574
    Abstract: The present invention relates to novel compositions of and methods of manufacture of controlled release formulations obtained by mixing molten drugs with molten additives to produce homogeneous drug-additive composites.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: September 15, 1998
    Assignee: Abbott Laboratories
    Inventors: Howard Cheskin, Thomas J. Hale, Kurt G. Van Scoik, Ji Zhou