Patents by Inventor Howard D. Beall

Howard D. Beall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DT-diaphorase directed anti-tumor agents
    Patent number: 6156744
    Abstract: The present invention relates to a novel benzoquinone, 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone and its esters. The compounds can be used to treat tumors exhibiting elevated levels of the enzyme DT-diaphorase.
    Type: Grant
    Filed: May 24, 1999
    Date of Patent: December 5, 2000
    Assignees: Cancer Research Campaign Tech (London), University Technology Corp., University of Salford
    Inventors: David Ross, John Butler, Robert H. J. Hargreaves, David Siegel, Howard D. Beall
  • Topical 5-fluorouracil prodrug composition and method
    Patent number: 5610160
    Abstract: A pharmaceutical composition in unit dosage form adapted for topical administration to a human or non-human animal in need thereof comprising a pharmacologically effective amount of a prodrug of 5-fluorouracil having the formula: ##STR1## wherein R.sub.3 is bonded to C=O by a carbon-to-carbon bond and is a group such that the prodrug (1) has an enhanced delivery across topical membranes and (2) hydrolyzes after delivery to 5-fluorouracil.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: March 11, 1997
    Inventors: Kenneth B. Sloan, Howard D. Beall