Patents by Inventor Howard David Dean
Howard David Dean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230380877Abstract: A device used in conjunction with fixation hardware to provide a two-stage process to address the competing needs of immobilization and re-establishment of normal stress-strain trajectories in grafted bone. A method of determining a patient-specific stress/strain pattern that utilizes a model based on 3D CT data of the relevant structures and cross-sectional data of the three major chewing muscles. The forces on each of the chewing muscles are determined based on the model using predetermined bite forces such that a stiffness of cortical bone in the patient's mandible is determined. Based on the stiffness data, suitable implantation hardware can be designed for the patient by adjusting external topological and internal porous geometries that reduce the stiffness of biocompatible metals to thereby restore normal bite forces of the patient. A method of 3D printing nitinol to create a patient-specific device to facilitate the establishment of a normal stress-strain trajectory in grafted bone.Type: ApplicationFiled: January 18, 2023Publication date: November 30, 2023Inventors: Howard David Dean, Mohammad H. Elahinia, Christoph Haberland, Michael J. Miller, Alok Sutradhar, Narges Shayesteh Moghaddam, Jason M. Walker, Roman Skoracki
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Patent number: 11628001Abstract: A device used in conjunction with fixation hardware to provide a two-stage process to address the competing needs of immobilization and re-establishment of normal stress-strain trajectories in grafted bone. A method of determining a patient-specific stress/strain pattern that utilizes a model based on 3D CT data of the relevant structures and cross-sectional data of the three major chewing muscles. The forces on each of the chewing muscles are determined based on the model using predetermined bite forces such that a stiffness of cortical bone in the patient's mandible is determined. Based on the stiffness data, suitable implantation hardware can be designed for the patient by adjusting external topological and internal porous geometries that reduce the stiffness of biocompatible metals to thereby restore normal bite forces of the patient.Type: GrantFiled: March 11, 2015Date of Patent: April 18, 2023Assignees: OHIO STATE INNOVATION FOUNDATION, THE UNIVERSITY OF TOLEDOInventors: Howard David Dean, Mohammad H. Elahinia, Christoph Haberland, Michael J. Miller, Alok Sutradhar, Narges Shayesteh Moghaddam, Jason M. Walker, Roman Skoracki
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Publication number: 20190001027Abstract: A Quaternary Mg—Zn—Ca-based alloy and a heat treatment process for producing bioresorbable bone fixation implants are described thereof. The mechanical and biocorrosion properties of the fabricated Mg-based alloy were improved by combining careful selection of the alloy's chemical composition and subsequent post-shaping process (heat treatments). Heat treatment process is more privileged especially after fabricating the part into its final shape such as in additive manufacturing (3D-printing) and powder metallurgy. In this way, it is possible to produce biocompatible, strong and less corrosive patient-specific bone fixation hardware. Also, such heat-treated Mg—Zn—Ca-based parts can be further coated with various types of biocompatible ceramic coatings for slower and more tailored biocorrosion rates.Type: ApplicationFiled: December 21, 2016Publication date: January 3, 2019Applicants: The University of Toledo, Ohio State UniversityInventors: Hamdy IBRAHIM, Mohammad ELAHINIA, Howard David DEAN
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Publication number: 20180189421Abstract: Determining a shape of a medical device to be implanted into a subject produces an image including a defective portion and a non-defective portion of a surface of a tissue of interest included in the subject. The tissue of interest is segmented within the image. A template, representing a normative shape of an external anatomical surface of the tissue of interest, is superimposed to span the defective portion. An external shape of an implant, is determined as a function of respective shapes of the defective portion as seen in the template, for repairing the defective portion.Type: ApplicationFiled: March 1, 2018Publication date: July 5, 2018Inventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T. Moullas, Robert A. Ratcheson
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Publication number: 20180032641Abstract: Determining a shape of a medical device to be implanted into a subject produces an image including a defective portion and a non-defective portion of a surface of a tissue of interest included in the subject. The tissue of interest is segmented within the image. A template, representing a normative shape of an external anatomical surface of the tissue of interest, is superimposed to span the defective portion. An external shape of an implant, is determined as a function of respective shapes of the defective portion as seen in the template, for repairing the defective portion.Type: ApplicationFiled: June 5, 2017Publication date: February 1, 2018Inventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T. Moullas, Robert A. Ratcheson
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Patent number: 9672302Abstract: Determining a shape of a medical device to be implanted into a subject produces an image including a defective portion and a non-defective portion of a surface of a tissue of interest included in the subject. The tissue of interest is segmented within the image. A template, representing a normative shape of an external anatomical surface of the tissue of interest, is superimposed to span the defective portion. An external shape of an implant, is determined as a function of respective shapes of the defective portion as seen in the template, for repairing the defective portion.Type: GrantFiled: March 21, 2016Date of Patent: June 6, 2017Assignee: Osteoplastics, LLCInventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T. Moullas, Robert A. Ratcheson
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Publication number: 20170014169Abstract: A device used in conjunction with fixation hardware to provide a two-stage process to address the competing needs of immobilization and re-establishment of normal stress-strain trajectories in grafted bone. A method of determining a patient-specific stress/strain pattern that utilizes a model based on 3D CT data of the relevant structures and cross-sectional data of the three major chewing muscles. The forces on each of the chewing muscles are determined based on the model using predetermined bite forces such that a stiffness of cortical bone in the patient's mandible is determined. Based on the stiffness data, suitable implantation hardware can be designed for the patient by adjusting external topological and internal porous geometries that reduce the stiffness of biocompatible metals to thereby restore normal bite forces of the patient.Type: ApplicationFiled: March 11, 2015Publication date: January 19, 2017Inventors: Howard David Dean, Mohammad H. Elahinia, Christoph Haberland, Michael J. Miller, Alok Sutradhar, Narges Shayesteh Moghaddam, Jason M. Walker, Roman Skoracki
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Publication number: 20160203241Abstract: Determining a shape of a medical device to be implanted into a subject produces an image including a defective portion and a non-defective portion of a surface of a tissue of interest included in the subject. The tissue of interest is segmented within the image. A template, representing a normative shape of an external anatomical surface of the tissue of interest, is superimposed to span the defective portion. An external shape of an implant, is determined as a function of respective shapes of the defective portion as seen in the template, for repairing the defective portion.Type: ApplicationFiled: March 21, 2016Publication date: July 14, 2016Inventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T. Moullas, Robert A. Ratcheson
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Patent number: 9330206Abstract: Determining a shape of a medical device to be implanted into a subject produces an image including a defective portion and a non-defective portion of a surface of a tissue of interest included in the subject. The tissue of interest is segmented within the image. A template, representing a normative shape of an external anatomical surface of the tissue of interest, is superimposed to span the defective portion. An external shape of an implant, is determined as a function of respective shapes of the defective portion as seen in the template, for repairing the defective portion.Type: GrantFiled: May 14, 2014Date of Patent: May 3, 2016Assignee: Osteoplastics LLCInventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T Moullas, Robert A Ratcheson
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Patent number: 9292920Abstract: A computer implemented method for determining the 3-dimensional shape of an implant to be implanted into a subject includes obtaining a computer readable image including a defective portion and a non-defective portion of tissue in the subject, superimposing on the image a shape to span the defective portion, and determining the 3-dimensional shape of the implant based on the shape that spans the defective portion.Type: GrantFiled: May 15, 2014Date of Patent: March 22, 2016Assignee: Osteoplastics, LLCInventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T Moullas, Robert A Ratcheson
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Publication number: 20150032421Abstract: Determining a shape of a medical device to be implanted into a subject produces an image including a defective portion and a non-defective portion of a surface of a tissue of interest included in the subject. The tissue of interest is segmented within the image. A template, representing a normative shape of an external anatomical surface of the tissue of interest, is superimposed to span the defective portion. An external shape of an implant, is determined as a function of respective shapes of the defective portion as seen in the template, for repairing the defective portion.Type: ApplicationFiled: May 14, 2014Publication date: January 29, 2015Applicant: OSTEOPLASTICS LLCInventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T. Moullas, Robert A. Ratcheson
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Publication number: 20140301627Abstract: A computer implemented method for determining the 3-dimensional shape of an implant to be implanted into a subject includes obtaining a computer readable image including a defective portion and a non-defective portion of tissue in the subject, superimposing on the image a shape to span the defective portion, and determining the 3-dimensional shape of the implant based on the shape that spans the defective portion.Type: ApplicationFiled: May 15, 2014Publication date: October 9, 2014Applicant: OSTEOPLASTICS LLCInventors: Howard David Dean, Krishnamoorthy Subramanyan, Alexandros T. Moullas, Robert A. Ratcheson
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Patent number: 7702380Abstract: A shape of a medical device to be implanted into a subject is verified by acquiring a plurality of inter-fiduciary marker dimensions from the subject. Three-dimensional image data of the markers and a tissue of interest, included in the subject, is obtained. Respective measurements between the fiduciary markers around the subject and in the image data are confirmed. The tissue of interest and the fiduciary markers are identified in the image data. Points of the tissue of interest and the fiduciary markers are rendered as a 3-dimensional surface representation. A 3-dimensional model of the tissue of interest and the fiduciary markers is generated as a function of the surface representation. A shape of the medical device to be implanted into the subject is determined as a function of the 3-dimensional model.Type: GrantFiled: November 3, 2000Date of Patent: April 20, 2010Assignee: Case Western Reserve UniversityInventor: Howard David Dean