Patents by Inventor Howard E. Bond

Howard E. Bond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Site-specific conjugation of immunoglobulins and detectable labels
    Patent number: 5191066
    Abstract: A process for producing a derivatized immunoglobulin and conjugates prepared therewith are provided. The derivatized immunoglobulin is produced by introducing sulfhydryl groups in the Fc region of an immunoglobulin wherein the Fab portion of the immunoglobulin is not altered. The derivatized immunoglobulin is used to prepare conjugates with various detectable moieties wherein a controlled distance exists between the Fc region of the immunoglobulin and the detectable moiety. The conjugates are particularly useful for performing immunoassays, and exhibit improved longevity, specificity and sensitivity.
    Type: Grant
    Filed: December 7, 1990
    Date of Patent: March 2, 1993
    Assignee: Abbott Laboratories
    Inventors: Christopher Bieniarz, Mazhar Husain, Howard E. Bond