Patents by Inventor Howard Eugene Magadanz

Howard Eugene Magadanz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reductive alkylation of glycopeptide antibiotics
    Patent number: 5998581
    Abstract: This invention is concerned with improved processes for reductive alkylation of glycopeptide antibiotics. The improvement residing in providing a source of copper which results in the initial production of a copper complex of the glycopeptide antibiotic. Reductive alkylation of this complex favors regioselective alkylation and increased yields. Copper complexes of the glycopeptide antibiotic starting materials and of the alkylated products are also part of the invention.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: December 7, 1999
    Assignee: Eli Lilly and Company
    Inventors: Richard Alan Berglund, Nancy Anne Lockwood, Howard Eugene Magadanz, Hua Zheng
  • Reductive alkylation of glycopeptide antibiotics
    Patent number: 5952466
    Abstract: This invention is concerned with improved processes for reductive alkylation of glycopeptide antibiotics. The improvement residing in providing a source of copper which results in the initial production of a copper complex of the glycopeptide antibiotic. Reductive alkylation of this complex favors regioselective alkylation and increased yields. Copper complexes of the glycopeptide antibiotic starting materials and of the alkylated products are also part of the invention.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: September 14, 1999
    Assignee: Eli Lilly and Company
    Inventors: Richard Alan Berglund, Nancy Anne Lockwood, Howard Eugene Magadanz, Hua Zheng