Patents by Inventor Howard Fine

Howard Fine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210252011
    Abstract: The present disclosure relates to methods of treating glioblastoma by administering to a patient in need thereof a FASN inhibitor.
    Type: Application
    Filed: October 25, 2018
    Publication date: August 19, 2021
    Inventors: Wei LU, Matthew W. MARTIN, Erik WILKER, Howard FINE
  • Publication number: 20100331858
    Abstract: Systems, devices, and methods for robot-assisted microsurgical stenting are described herein. In some embodiments a tele-robotic microsurgical system for eye surgery include: a tele-robotic master and a slave hybrid-robot; wherein the tele-robotic master has at least one master slave interface controlled by a medical professional; wherein the slave hybrid-robot has at least one robotic arm attached to a frame releasably attached to a patient's head; wherein the at least one robotic arm has a parallel robot and a serial robot; and wherein the serial robot includes a stenting unit which includes a support tube, a pre-bent tube mounted within the support tube and a guide wire extending from the support tube for carrying a stent and for piercing a blood vessel.
    Type: Application
    Filed: January 30, 2009
    Publication date: December 30, 2010
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Nabil Simaan, Howard Fine, Wei Wei, Stanley Chang
  • Publication number: 20100010504
    Abstract: Systems, devices, and methods for surgery on a hollow anatomically suspended organ are described herein. In some embodiments a tele-robotic microsurgical system for eye surgery include: a tele-robotic master and a slave hybrid-robot; wherein the tele-robotic master has at least two master slave interfaces controlled by a medical professional; wherein the slave hybrid-robot has at least two robotic arms attached to a frame releasably attached to a patient's head; wherein the at least two robotic arms each have a parallel robot and a serial robot; and wherein the serial robot includes a tube housing a cannula.
    Type: Application
    Filed: September 19, 2007
    Publication date: January 14, 2010
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Nabil Simaan, Wei Wei, Roger Goldman, Howard Fine, Stanley Chang
  • Publication number: 20060286117
    Abstract: The present invention relates to methods of promoting or inhibiting angiogenesis in humans comprising administering to a human in need thereof an effective amount of Stem Cell Factor or a modulator of Stem Cell Factor or an agonist or antagonist of c-Kit and methods of inducing migration of a neural stem or progenitor cell to a site of neurological injury in the central nervous system of a subject.
    Type: Application
    Filed: May 24, 2006
    Publication date: December 21, 2006
    Inventors: Howard Fine, Lixin Sun
  • Patent number: 6423692
    Abstract: A method of increasing the effectiveness of molecules that can be phosphorylated by dCK is described. This method involves transducing cells with the gene for deoxycytidine kinase which can chemosensitize the cell to molecules that are phosphorylated by dCK.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: July 23, 2002
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Howard A. Fine, Donald Kufe, Yoshinobu Manome
  • Publication number: 20010012835
    Abstract: A method of increasing the effectiveness of molecules that can be phosphorylated by dCK is described. This method involves transducing cells with the gene for deoxycytidine kinase which can chemosensitize the cell to molecules that are phosphorylated by dCK.
    Type: Application
    Filed: April 24, 1998
    Publication date: August 9, 2001
    Inventors: HOWARD A FINE, DONALD W. KUFE, YOSHINOBU MANOME
  • Patent number: 4454110
    Abstract: A self-gelling composition for topical application, particularly in the oral cavity, which composition comprises: an aqueous solution of ethyl orthosilicate monomer or prepolymer; an active ingredient, such as a fluoride, or an antibiotic for sustained release in the area of topical application; and a gelation agent, to provide, on mixing of the composition, the in situ gelling of the composition within a predetermined time period after topical application, to provide the penetration properties of a low-viscosity solution with the sustained release of the active ingredient from the gel.
    Type: Grant
    Filed: August 1, 1983
    Date of Patent: June 12, 1984
    Assignee: Forsyth Dental Infirmary for Children
    Inventors: Vera B. Caslavsky, Poul Gron, Howard Fine
  • Patent number: 4411889
    Abstract: A self-gelling composition for topical application, particularly in the oral cavity, which composition comprises: an aqueous solution of ethyl orthosilicate monomer or prepolymer; an active ingredient, such as a fluoride, or an antibiotic for sustained release in the area of topical application; and a gelation agent, to provide, on mixing of the composition, the in situ gelling of the composition within a predetermined time period after topical application, to provide the penetration properties of a low-viscosity solution with the sustained release of the active ingredient from the gel.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: October 25, 1983
    Assignee: Forsyth Dental Infirmary for Children
    Inventors: Vera B. Caslavsky, Poul Gron, Howard Fine