Patents by Inventor Howard G. Selnick

Howard G. Selnick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazobenzazepine CGRP receptor antagonists
    Patent number: 8796260
    Abstract: Compounds of Formula I: I (where variables R1A, R1B, R2, R3, R4, A, and Z are as defined herein) useful as antagonists of CGRP receptors, and useful in the treatment or prevention of diseases in which CGRP receptors are involved, such as headache, and in particular migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP receptors are involved.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: August 5, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Howard G. Selnick, Ian M. Bell
  • Monocyclic amide CGRP receptor antagonists
    Patent number: 8362005
    Abstract: Compounds of formula (I): wherein variables B, m, n, J, R4, Ea, Eb, Ec, Re, Rf, RPG and Y are as described herein, which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: January 29, 2013
    Assignee: Merk. Sharp & Dohme Corp.
    Inventors: Ian M. Bell, Howard G. Selnick
  • MONOCYCLIC AMIDE CGRP RECEPTOR ANTAGONISTS
    Publication number: 20110172205
    Abstract: Compounds of formula (I): wherein variables B, m, n, J, R4, Ea, Eb, Ec, Rf, RPG and Y are as described herein, which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: August 31, 2009
    Publication date: July 14, 2011
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Ian M. Bell, Howard G. Selnick
  • IMIDAZOBENZAZEPINE CGRP RECEPTOR ANTAGONISTS
    Publication number: 20100324023
    Abstract: Compounds of Formula I: I (where variables R1A, R1B, R2, R3, R4, A, and Z are as defined herein) useful as antagonists of CGRP receptors, and useful in the treatment or prevention of diseases in which CGRP receptors are involved, such as headache, and in particular migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP receptors are involved.
    Type: Application
    Filed: February 6, 2009
    Publication date: December 23, 2010
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Howard G. Selnick, Ian M. Bell