Patents by Inventor Howard Glenn Welgus

Howard Glenn Welgus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME
    Publication number: 20180185325
    Abstract: The present invention provides compounds of the following structure, methods of using such compounds, and pharmaceutical compositions containing such compounds. In addition, this invention provides methods for the treatment and/or prevention of disease states mediated by Aryl Hydrocarbon receptor pathways.
    Type: Application
    Filed: June 8, 2016
    Publication date: July 5, 2018
    Applicant: Thesan Pharmaceuticals, Inc.
    Inventors: Nigel Robert Arnold Beeley, Howard Glenn Welgus, Jay Edward Birnbaum, J. Gordon Foulkes, Celia Patricia Jenkinson, Jean Hilaire Saurat
  • 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME
    Publication number: 20180179174
    Abstract: The present invention provides compounds of the following structure, methods of using such compounds, and pharmaceutical compositions containing such compounds. In addition, this invention provides methods for the treatment and/or prevention of disease states mediated by Aryl Hydrocarbon receptor pathways.
    Type: Application
    Filed: June 6, 2016
    Publication date: June 28, 2018
    Applicant: Thesan Pharmaceuticals, Inc.
    Inventors: Nigel Robert Arnold Beeley, Howard Glenn Welgus, Jay Edward Birnbaum, J. Gordon Foulkes, Celia Patricia Jenkinson, Jean Hilaire Saurat
  • BETA-NAPHTHOISOFLAVONES, COMPOSITIONS CONTAINING, AND USES OF, SAME
    Publication number: 20180118707
    Abstract: The present invention provides compounds of the following structure, methods of using such compounds, and pharmaceutical compositions containing such compounds. In addition, this invention provides methods for the treatment and/or prevention of disease states mediated by Aryl Hydrocarbon receptor pathways.
    Type: Application
    Filed: June 7, 2016
    Publication date: May 3, 2018
    Applicant: Thesan Pharmaceuticals, Inc.
    Inventors: Nigel Robert Arnold Beeley, Howard Glenn Welgus, Jay Edward Birnbaum, J. Gordon Foulkes, Celia Patricia Jenkinson, Jean Hilaire Saurat
  • Method of treating noninflammatory cartilage damage
    Patent number: 7189747
    Abstract: The invention relates to a method of preventing or treating cartilage damage by administering a GABA analog such as, for example, a compound of Formula and pharmaceutically acceptable salts thereof, wherein R1 is hydrogen or straight or branched lower alkyl, and n is an integer of from 4 to 6.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: March 13, 2007
    Assignee: Warner-Lambert Company
    Inventors: Denis Schrier, Howard Glenn Welgus, David Juergen Wustrow
  • Method of treating cartilage damage
    Publication number: 20040097405
    Abstract: The invention relates to a method of preventing or treating cartilage damage by administering a GABA analog such as, for example, a compound of Formula 1
    Type: Application
    Filed: June 23, 2003
    Publication date: May 20, 2004
    Inventors: Denis Schrier, Howard Glenn Welgus, David Juergen Wustrow
  • Method of treating noninflammatory cartilage damage
    Patent number: 6620829
    Abstract: The invention relates to a method of treating non inflammatory cartilage damage by administering a GABA analog of Formula: and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: September 16, 2003
    Assignee: Warner-Lambert Company
    Inventors: Denis Schrier, Howard Glenn Welgus, David Juergen Wustrow
  • Method of treating cartilage damage
    Publication number: 20020072533
    Abstract: The invention relates to a method of preventing or treating cartilage damage by administering a GABA analog such as, for example, a compound of Formula 1
    Type: Application
    Filed: September 14, 2001
    Publication date: June 13, 2002
    Inventors: Denis Schrier, Howard Glenn Welgus, David Juergen Wustrow
  • Method of inhibiting connective tissue degradation
    Patent number: 6211209
    Abstract: The present invention provides a method of inhibiting connective tissue degradation that comprises administering to a patient having a condition in which connective tissue is degraded a therapeutically effective amount of a compound having the formula where R1, R2, R3, and R4 are independently hydrogen, hydroxy, halo, amino, nitro, C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, CF3, CN, S(O)n—, R6 and R7 are independently hydrogen, C1-C6 alkyl, or acyl; n is 0 to 2; R8 is hydrogen or C1-C6 alkyl; W is S or O; Z is C1-C6 alkyl, C1-C6 alkoxy, or NR9R10; R9 and R10 are independently hydrogen or C1-C6 alkyl; and R5 is where Y is hydroxy, thiol, amino, or NHCN; X is sulfur or oxygen; and Q is sulfur, oxygen, NH, or NCN, and the pharmaceutically acceptable salts and prodrugs thereof.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: April 3, 2001
    Assignee: Warner-Lambert Company
    Inventors: Vijaykumar Baragi, Diane Harris Boschelli, David Thomas Connor, Richard Raymond Renkiewicz, Howard Glenn Welgus