Patents by Inventor Howard H. T. Hsu

Howard H. T. Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2
    Patent number: 6020313
    Abstract: The invention relates to a method for inducing bone formation via administration of an extract of devitalized, freeze dried Saos-2 cells. The extract is prepared by contacting the freeze dried Saos-2 cells, which are devitalized in the act of freeze drying, with a weak denaturing agent of the type used to separate proteins from cells. The extract does have properties superior to comparable treatment using whole Saos-2 cells. The extract is then further treated by applying it to a removing separating gel, and then fractions from the gel which have a molecular weight of from about 10 kd to about 60 kd. Also described are the extract itself, and formulations containing it.
    Type: Grant
    Filed: February 8, 1993
    Date of Patent: February 1, 2000
    Assignee: University of Kansas
    Inventors: H. Clarke Anderson, Howard H. T. Hsu