Patents by Inventor Howard Jacobs

Howard Jacobs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic and screening method for male infertility
    Publication number: 20050130202
    Abstract: The present invention relates to a novel diagnostic method for the detection of infertility in males. In particular, the present invention relates to a diagnostic method for detecting the presence or absence of a mutation or mutations in the POLG gene encoding mitochondrial DNA polmerase in a biological sample. The invention relates also to the use of a mutant POLG gene in the detection of infertility in males and in the screening of human populations for the presence of such mutation or mutations as a predictive test for male infertility. The invention also relates to the use of the POLG gene as an indicator of other pathological conditions associated with or related to male infertility, including those manifesting in women.
    Type: Application
    Filed: November 1, 2004
    Publication date: June 16, 2005
    Applicant: LICENTIA OY
    Inventors: Howard Jacobs, Anja Rovio
  • Method of diagnosing and screening for male infertility through mutations in POLG
    Patent number: 6811976
    Abstract: The present invention relates to a novel diagnostic method for the detection of infertility in males. In particular, the present invention relates to a diagnostic method for detecting the presence or absence of a mutation or mutations in the POLG gene encoding mitochondrial DNA polmerase in a biological sample. The invention relates also to the use of a mutant POLG gene in the detection of infertility in males and in the screening of human populations for the presence of such mutation or mutations as a predictive test for male infertility. The invention also relates to the use of the POLG gene as an indicator of other pathological conditions associated with or related to male infertility, including those manifesting in women.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: November 2, 2004
    Assignee: Licentia Oy
    Inventors: Howard Jacobs, Anja Rovio
  • Method for treating infertility comprising administering GnRH analog, gonadotrophins, and growth hormone
    Patent number: 5538948
    Abstract: A combination of GnRH analog, gonadotrophins, and growth hormone is very useful for treating infertility in higher mammals and humans since the probability of pregnancy is enhanced and the total doses of gonadotrophins are reduced. The treatment is initiated with administration of GnRH analog and continued with administration of gonadotrophins and growth hormone.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: July 23, 1996
    Assignee: Novo Nordisk A/S
    Inventor: Howard Jacobs