Abstract: Agonist analogues of amylin and related pharmaceutical compositions, and methods of treatment of diabetes and other insulin-requiring states, as well as methods of treatment of hypoglycemia, are provided.

Abstract: A closed loop continuous emulsion polymerization apparatus at least comprising a circulation pump, a reactor tube which connects the outlet of the circulation pump to its inlet, at least one feed for supplying raw materials, an outlet, and means for cooling the tube, characterized in that the reactor further comprises an additional tube for by-passing a pig around the circulation pump, a pig receiving station which is in parallel connection with the circulation pump or the reactor tube, and optionally means for directing a pig into the pig receiving station. The invention allows simple removal of the pig from the reactor, afforts great freedom in selecting the type of circulation pump and material and shape of the pig, and enables total control over the launching of the pig substantially independent of the reaction medium flow.

Abstract: This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R1 to R4 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodeficiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).

Abstract: This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R1 to R4 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodeficiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).

Abstract: This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R1 to R4, n W, X and Y are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).

Abstract: An electronic inspection report system includes a central report generator and a data collection device. The central report generator is adapted to produce multiple types of inspection report template. The central report generator is adapted to select a type of inspection report template to provide to a data collection device based upon various criteria. The central report generator is adapted to receive electronic information from various databases and format the information such that the information can be used in inspection reports. While inspecting an item, an inspector uses a data collection device to access an inspection report template and fill in fields of the inspection report template. The data collection device can be configured to check the consistency of information carried in fields of the inspection report and signal the inspector when some of the information is inconsistent. The central report generator can include a repository of completed inspection reports.

Abstract: This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such, the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).

Abstract: Disclosed are substituted indolealkanoic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.

Abstract: This invention relates to pyrazole derivatives of formula (I) 1

Abstract: Disclosed are substituted indolealkanoic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.

Abstract: Agonist analogues of amylin and related pharmaceutical compositions, and methods of treatment of diabetes and other insulin-requiring states, as well as methods of treatment of hypoglycemia, are provided.

Abstract: Agonist analogs of amylin and related pharmaceutical compositions, and methods of treatment of diabetes and other insulin-requiring states, as well as methods of treatment of hypoglycemia, are provided.

Abstract: This invention relates to pyrazole derivatives of formula (I) 1

Abstract: Agonist analogs of amylin and related pharmaceutical compositions, and methods of treatment of diabetes and other insulin-requiring states, as well as methods of treatment of hypoglycemia, are provided.

Abstract: The present invention is directed to a method and system for distributing or obtaining incentives related to the purchase or acquisition of a product or a service, whereby the incentive can be offered on condition that the purchaser of the product or service agrees to receive an interposed communication, which can be any multimedia message including advertisement, informative information, or survey.

Abstract: A seal between two static turbine parts is provided with a carrier piece comprising a flat metal piece with a middle piece and end pieces each of which is arranged in a groove in the static turbine parts. A second part comprising a flat metal piece and having a middle piece and end pieces which are also arranged in grooves is attached to the middle piece of the carrier. The end pieces are constructed resiliently, ensuring a sealing contact between the end pieces and the inside surfaces of the grooves even in the case of a relative shift of the grooves. The seal does not depend on the level of a pressure differential.

Abstract: Disclosed are substituted indolealkanoic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.

Abstract: A computing device to classify, manipulate, store, search, and selectively retrieve items from image databases, using a method & apparatus including a computer processor to analyze the configured disposition of a multiplicity of linear motion paths that constitute a glyph delineated within a defined planar rendering area and to process, manipulate, and compare data representing said configured disposition of said linear motion paths, comprising (a) a template analytic lattice constituted of a predetermined multiplicity of cell partitions, the totality of the analytic lattice being coextensive with the defined rendering area of the glyph and in the plane of motion of the linear motion paths of the glyph; (b) means of interpreting each linear motion path as a sequence of displacement vectors, determining which displacement vectors intersect specific boundaries of specific cells of the analytic lattice, and registering each cell boundary intersection by both recording the intersecting vector inclination grad

Abstract: The present invention is directed to a method and system for distributing or obtaining products covered by intellectual property over a telecommunications network whereby a consumer may, rather paying for the products, choose to receive such products after viewing and/or interacting with an interposed sponsor's or advertiser's message, wherein the interposed sponsor or advertiser may pay the owner or assignee of the underlying intellectual property associated with the product through an intermediary such as a facilitator.

Abstract: An aromatic carboxylic acid such as terephthalic acid is produced by the liquid phase oxidation of a precursor thereof, the oxidation being carried out in such a way that substantially all of the aromatic carboxylic acid produced in the course of the reaction is maintained in solution during the reaction.