Patents by Inventor Howard L. Johnson
Howard L. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 5242936Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 is at position 4 and either is an alkyl group of 1-6 C or is an --(CH.sub.2).sub.3 -- which is additionally linked to the phenyl at position 3 thereof;R.sub.2 is a lower alkyl of 1-3 C or is hydrogen;n.sub.1, n.sub.2 and n.sub.3 represent the number of CH.sub.2, C(R.sub.2).sub.2 and CH.sub.2 groups, respectively, wherein n.sub.1 is 2, 3, 4, 5, 6, 8, or 11, n.sub.2 is 0 or 1 and n.sub.3 is 0 andR.sub.4 is an alkyl residue of 1-12 C or is selected from phenyl and pyridyl; and their pharmaceutical compositions are useful in inhibiting the release of chemical mediators which cause allergic symptoms. Compounds, compositions, and methods for treatment of allergic conditions are disclosed.Type: GrantFiled: May 21, 1990Date of Patent: September 7, 1993Assignee: Frank M. BergerInventors: Frank M. Berger, Joseph I. DeGraw, Jr., Howard L. Johnson
-
Patent number: 5021460Abstract: p-Alkyl or cycloalkyl phenoxy alkanols and esters are provided having the structure: ##STR1## in which: R.sub.1 is an alkyl group having from one to six carbon atoms, preferably tertiary, and still more preferably tertiary-butul; or a bivalent cycloalkylene group condensed with the phenyl group at adjacent ring carbons thereof, such as in indane;R.sub.2 is lower alkyl having from one to three carbon atoms or hydrogen;R.sub.3 is hydroxyl or an ester group selected from the group consisting of COOR.sub.4 and OOCR.sub.4 derived from unsubstituted and hydroxy-substituted monocarboxylic acids and COOR.sub.5 OOC and OOCR.sub.Type: GrantFiled: December 22, 1988Date of Patent: June 4, 1991Assignee: Frank M. BergerInventors: Frank M. Berger, Howard L. Johnson, Joseph I. DeGraw, Jr.
-
Patent number: 4816491Abstract: p-Allyl or cycloalkyl phenoxy alkanols and esters are provided having the structure: ##STR1## in which: R.sub.1 is an alkyl group having from one to six carbon atoms, preferably tertiary, and still more preferably tertiary-butyl; or a bivalent cycloalkylene group condensed with the phenyl group at adjacent ring carbons thereof, such as in indane;R.sub.2 is lower alkyl having from one to three carbon atoms or hydrogen;R.sub.3 is hydroxyl or an ester group selected from the group consisting of COOR.sub.4 and OOCR.sub.4 derived from unsubstituted and hydroxy-substituted monocarboxylic acids and COOR.sub.5 OOC and OOCR.sub.Type: GrantFiled: May 7, 1987Date of Patent: March 28, 1989Assignee: Frank M. BergerInventors: Frank M. Berger, Joseph I. Degraw, Howard L. Johnson
-
Patent number: 4543362Abstract: p-Alkyl or cycloalkyl phenoxy alkanols and esters are provided having the structure: ##STR1## in which: R.sub.1 is an alkyl group having from one to six carbon atoms, preferably tertiary, and still more preferably tertiary-butyl; or a bivalent cycloalkylene group condensed with the phenyl group at adjacent ring carbons thereof, such as in indane;R.sub.2 is lower alkyl having from one to three carbon atoms or hydrogen;R.sub.3 is hydroxyl or an ester group selected from the group consisting of COOR.sub.4 and OOCR.sub.4 derived from unsubstituted and hydroxy-substituted monocarboxylic acids and COOR.sub.5 OOC and OOCR.sub.Type: GrantFiled: January 13, 1984Date of Patent: September 24, 1985Assignee: Frank M. BergerInventors: Frank M. Berger, Joseph I. DeGraw, Jr., Howard L. Johnson
-
Patent number: 4451474Abstract: p-Alkyl or cycloalkyl phenoxy alkanols and esters are provided having the structure: ##STR1## in which: R.sub.1 is an alkyl group having from one to six carbon atoms, preferably tertiary, and still more preferably tertiary-butyl; or a bivalent cycloalkylene group condensed with the phenyl group at adjacent ring carbons thereof, such as in indane;R.sub.2 is lower alkyl having from one to three carbon atoms or hydrogen;R.sub.3 is hydroxyl or an ester group selected from the group consisting of COOR.sub.4 and OOCR.sub.4 derived from unsubstituted and hydroxy-substituted monocarboxylic acids and COOR.sub.5 OOC and OOCR.sub.Type: GrantFiled: December 3, 1981Date of Patent: May 29, 1984Assignee: Frank M. BergerInventors: Frank M. Berger, Joseph I. DeGraw, Jr., Howard L. Johnson
-
Patent number: 4367884Abstract: A removable gooseneck for detachably connecting a tractor and trailer utilizes an elongate beam member attached to the hitch of the tractor and having an upstanding frame member depending from a rear end of the beam member. A foot is pivotally mounted at a lower end of the upstanding frame member for engagement with a front end portion of the trailer. A guide pin and link arrangement detachably connects the foot at a front end to the trailer and a locking pin and bushing arrangement detachably connects the rear end of the foot to the trailer at a location spaced from the guide pin and link arrangement. A power fluid ram extends between an upper portion of the upstanding frame member and the foot to selectively cause the foot member to swing upwardly and tilt the trailer downwardly for detachment of the gooseneck from the trailer and swing the foot downwardly to tilt the trailer upwardly for drafting.Type: GrantFiled: December 15, 1980Date of Patent: January 11, 1983Inventors: Howard L. Johnson, David A. Kramer
-
Patent number: 4345436Abstract: Conditional exchanging of working fluid between plural fluid circuits (13A, 13B) having separate supply pumps (18A, 18B) is provided for without continuously bleeding fluid from the pump control pressure lines (21A, 21B). Each circuit (13A, 13B) has a pump control (19A, 19B) responsive to a control pressure, a plurality of fluid motors (14A, 15A, 16A, 14B, 15B, 16B), and a group of resolver valves (38A, 38B) which compare motor pressures and intercommunicate the pump control (19A, 19B) with the most highly pressurized motor (14A, 15A, 16A, 14B, 15B, 16B). At times when fluid from one circuit (13A, 13B) is being delivered to a motor (16A, 16B) of another circuit (13A, 13B), the pressure comparing function of the resolver group (38A, 38B) of the one circuit (13A, 13 B) is extended to include the motor (16A, 16B) of the other circuit (13A, 13B). Among other uses, the system (11) may be used on excavator vehicles having plural fluid motors performing a variety of different functions.Type: GrantFiled: April 7, 1980Date of Patent: August 24, 1982Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4269843Abstract: Novel N-sec-alkyl derivatives of norcodeine and normorphine wherein the sec-alkyl group contains either four or five carbon atoms. Specifically included are those derivatives of norcodeine and normorphine wherein the sec-alkyl group is 2-butyl, 3-pentyl, .alpha.-methylallyl and .alpha.-methylcyclopropylmethyl. The normorphine derivatives having strong agonist potency combined with strong antagonist qualities and indicated low addiction potential. The norcodeine analogs are useful as intermediates in preparing the corresponding normorphine compounds.Type: GrantFiled: July 8, 1980Date of Patent: May 26, 1981Assignees: SRI International, The Board of Trustees of Leland Stanford Jr. UniversityInventors: Joseph I. De Graw, John A. Lawson, Howard L. Johnson, Gilda H. Loew
-
Patent number: 4249842Abstract: A self loading multiple bale trailer comprises an elongated trailer frame with a belt conveyor extending from end to end and a lift fork for engagement at the lower periphery of a large round bale at the side of the trailer, for example, by forward motion of a tow vehicle. The lift fork is supported on a frame which is connected by an arm to a sleeve slidable on a verticle shaft and having an hydraulic cylinder for lifting the bale. The sleeve is also rotatable about a vertical axis to swing the lifted bale a half circle from the side of the trailer to a position over the conveyor for deposit thereon. The conveyor is operable to move the deposited bale to a desired position along the trailer, and may also be used to discharge the bale from the rear of the trailer or to reengage the lift fork with the bale. In an alternative form, the bale may be handled by a penetrating spike instead of lift fork legs, which spike may be utilized, in a quarter turn position, in unwinding the bale for feeding.Type: GrantFiled: September 28, 1978Date of Patent: February 10, 1981Inventor: Howard L. Johnson
-
Patent number: 4245816Abstract: A spool valve including a valve body having a bore intercepted by at least two axially spaced ports and a spool reciprocally received within the bore and having two axially spaced lands separated by a groove, one side wall of the groove being adjacent one of the lands and defining a shoulder. At least one shallow metering slot is disposed in the other of the lands and opens to the groove through another side wall thereof opposite from the first mentioned side wall. The slot has an increasing depth in the direction toward the groove and a cross sectional area taken transversely to the axis of the spool at any point along the slot less than the area of the top of the slot from the point to the end of the slot remote from the groove. An additional slot is disposed in the shoulder and opens to the groove, has a ramp-like bottom, and a width different from that of the metering slot.Type: GrantFiled: April 19, 1978Date of Patent: January 20, 1981Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4232986Abstract: A method for handling large cylindrical bales includes loading a first group of bales on an elongated trailer, elevating the bales, loading a second group of bales on the trailer, and lowering the first group of bales onto the second group for stable transportation of a relatively large number of bales. An apparatus for carrying out such a method includes the trailer having a conveyor extending therealong, a loader device on the trailer for engaging bales on the ground and depositing the same on the conveyor, bale supporting platform sections extending along the conveyor, drive shafts with sprockets thereon rotatably supported on the trailer and extending along the top side of the trailer, drive chains connected to the platform section and engaging the sprockets, and a motor operatively connected to shafts to rotate same and thereby effect elevation of the bales supported by the platform sections.Type: GrantFiled: September 28, 1978Date of Patent: November 11, 1980Inventor: Howard L. Johnson
-
Patent number: 4218454Abstract: Novel N-sec-alkyl derivatives of norcodeine and normorphine wherein the sec-alkyl group contains either four or five carbon atoms. Specifically included are those derivatives of norcodeine and normorphine wherein the sec-alkyl group is 2-butyl, 3-pentyl, .alpha.-methylallyl and .alpha.-methylcyclopropylmethyl. The normorphine derivatives have strong agonist potency combined with strong antagonist qualities and indicated low addiction potential. The norcodeine analogs are useful as intermediates in preparing the corresponding normorphine compounds.Type: GrantFiled: May 24, 1978Date of Patent: August 19, 1980Assignee: SRI InternationalInventors: Joseph I. DeGraw, John A. Lawson, Howard L. Johnson, Gilda H. Loew, Donald A. Berkowitz
-
Patent number: 4204459Abstract: A hydraulic system including a hydraulic pump, a hydraulic motor having at least one port and a hydraulic reservoir. A main spool valve is interposed between the motor and the pump and reservoir and has a spool shiftable between positions connecting the pump to the port, connecting the reservoir to the port, and blocking fluid flow to or from the port. A single combination check and flow control valve is interposed between the main spool valve and the port. A fluid responsive surface opens the combination valve to permit relatively free flow of fluid therethrough when the spool is in the first mentioned position thereof. A pressure responsive surface and a control valve provides for partial opening of the combination valve to meter fluid flow therethrough when the spool is in the second position thereof. A spring is operative to close the combination valve to prevent fluid flow therethrough when the spool is in the last mentioned position thereof.Type: GrantFiled: April 19, 1978Date of Patent: May 27, 1980Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4196588Abstract: A supply or demand margin valve for use in hydraulic systems having at least one load provided with hydraulic fluid under pressure by a main pump, a pilot pump and at least one control valve for the load. The margin valve includes a valve body having a bore with a spool reciprocally received within the bore. A first port in the body extends to the bore and is adapted to be connected to the pilot pump. A second port in the body extends to the bore and spaced in relation to the first port and is adapted to be connected to a component of a hydraulic system other than a pilot pump. A spring is disposed in the valve body for applying a biasing force to the spool to urge the spool in one direction and a third port is in fluid communication with the pressure responsive surface and is adapted to be connected to a main pump so as to apply a force to the spool to urge the spool in the same direction as the spring.Type: GrantFiled: May 1, 1978Date of Patent: April 8, 1980Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4184410Abstract: A hydraulic system including a bidirectional hydraulic motor having first and second fluid ports, a pump, a control valve for selectively connecting the pump to (a) the first port and venting the second port and (b) the second port and venting the first port, a modulating valve interposed between the pump and the control valve for varying flow from the pump to the control valve, a pilot for the modulating valve, and a resolver for selecting the lowest pressure at the motor ports and for directing a fluid signal proportional thereto to the pilot to control the modulating valve.Type: GrantFiled: March 15, 1978Date of Patent: January 22, 1980Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4147034Abstract: A hydraulic system including a pressure and flow compensated pump, a source of pilot fluid under pressure, a plurality of hydraulic circuits each including a work performing device, a plurality of controls, one for each circuit, each including a pilot operated flow valve for connecting the associated work performing device to the pump and an operator positioned valve connected to the pilot source for selectively directing pilot fluid to the corresponding flow valve, the work performing devices and the flow valves being connected in parallel.Type: GrantFiled: April 19, 1978Date of Patent: April 3, 1979Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4142282Abstract: A check valve comprises a housing defining a valve seat thereon and a valve member reciprocally mounted in the housing to normally engage the seat for blocking fluid flow therepast. Two pairs of split retaining members are mounted in axially spaced relationship on a stem of the valve member and are expanded axially thereon by a compression coil spring for biasing the valve member to its closed position. A stop member is secured on an end of the stem of the valve member to prevent movement of one pair of the retaining members therepast. A slot is formed axially through the stop member and extends partially in the stem of the valve member to expose an end of the spring. In assembling the valve, a tool is inserted into the slot to compress the spring whereby the one pair of retaining members may be mounted on the valve member, between the spring and the stop member.Type: GrantFiled: January 6, 1978Date of Patent: March 6, 1979Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4132245Abstract: A pilot-operated spool valve including a valve body, a bore in the body, ports in the body and extending to the bore, a spool in the bore and axially shiftable therein, at least one pilot associated with an end of the spool for applying a shifting force to the spool, at least one spring in the body for applying a biasing force to the spool, and an adjustment for the biasing spring including a rotatable and axially movable member received in the body and engaging the spring, a cam surface in the form of interengaging threads on the member and the body for axially moving the member in response to rotation thereof, a rotatable actuator for rotating the member, a mount for the actuator so that the actuator can rotate only and is restrained against axial movement, and an axially extendable connection between the actuator and the member.Type: GrantFiled: January 17, 1977Date of Patent: January 2, 1979Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4114516Abstract: A construction vehicle has a work implement, such as a bucket-carrying boom, pivotally mounted thereon to be raised and lowered by one or more double-acting hydraulic cylinders. A directional control valve is conditioned to selectively communicate pressurized fluid to the rod end of each cylinder, for example, through a check valve. When the fluid pressure in the rod end of the cylinder exceeds a predetermined level, a pilot signal will be communicated to a modulating valve which will open to closely control and modulate the flow of the fluid exhausted from the head end of the cylinder. A pilot relief valve is interconnected between the head end of the cylinder and the modulating valve to cooperate therewith to relieve excessive fluid pressures. The above system is duplicated for selectively pressurizing the head end of the cylinder and for exhausting the rod end thereof.Type: GrantFiled: October 15, 1976Date of Patent: September 19, 1978Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson
-
Patent number: 4089170Abstract: Pressurized fluid is supplied to fluid-driven mechanisms by a variable displacement supply pump through a check valve and a flow control valve. A compensator receiving a pressure feedback signal from the control valve side of the check valve increases pump displacement in response to a pressure signal drop and decreases pump displacement in response to a rise in the signal pressure to compensate for variations in demand. Part of the supply pump output is used to drive a small fluid motor which turns a small pressure signal-amplifying pump connected in parallel with the check valve. The check valve opens to transmit the variable displacement pump output to the driven mechanisms when the control valve is opened.Type: GrantFiled: May 9, 1977Date of Patent: May 16, 1978Assignee: Caterpillar Tractor Co.Inventor: Howard L. Johnson