Abstract: A method of facilitating formation of a via in an inorganic substrate may include applying a single-sided acidic wet etching process to a first surface of the inorganic substrate in a first state in which the inorganic substrate has a mask layer set covering a second surface of the inorganic substrate; and applying a double-sided acidic wet etching process to the first surface and the second surface of the inorganic substrate after completion of the single-sided acidic wet etching process and in a second state in which the inorganic substrate has had the mask layer set removed from the second surface of the inorganic substrate.

Abstract: A supervised learning processing (SLP) system and method provide cooperative operation of a network of supervised learning processors to concurrently distribute supervised learning processor training, generate predictions, provide prediction driven responses to input objects, and provide operational sequencing to concurrently control and distribute supervised learning processor training and provide predictive responses to input data. The SLP system can dynamically sequence SLP subsystem operations to improve resource utilization, training quality, and/or processing speed. A system monitor-controller can dynamically determine if process environmental data indicates initiation of dynamic subsystem processing sequencing. Concurrently training SLP's provides accurate predictions of input objects and responses thereto and enhances the network by providing high quality value predictions and responses and avoiding potential training and operational delays.

Abstract: A supervised learning processing (SLP) system and method provide cooperative operation of a network of supervised learning processors to concurrently distribute supervised learning processor training, generate predictions, provide prediction driven responses to input objects, and provide operational sequencing to concurrently control and distribute supervised learning processor training and provide predictive responses to input data. The SLP system can dynamically sequence SLP subsystem operations to improve resource utilization, training quality, and/or processing speed. A system monitor-controller can dynamically determine if process environmental data indicates initiation of dynamic subsystem processing sequencing. Concurrently training SLP's provides accurate predictions of input objects and responses thereto and enhances the network by providing high quality value predictions and responses and avoiding potential training and operational delays.

Abstract: The disclosure herein provides systems, methods, and devices for determining and displaying market relative positions and/or attributes of unique items. A visualization system for generating electronic visualizations of market-relative attributes of unique items comprises an item selection receiver, a visualization compilation engine, and a rendering engine.

Abstract: A supervised learning processing (SLP) system and method provide cooperative operation of a network of supervised learning processors to concurrently distribute supervised learning processor training, generate predictions, provide prediction driven responses to input objects, and provide operational sequencing to concurrently control and distribute supervised learning processor training and provide predictive responses to input data. The SLP system can dynamically sequence SLP subsystem operations to improve resource utilization, training quality, and/or processing speed. A system monitor-controller can dynamically determine if process environmental data indicates initiation of dynamic subsystem processing sequencing. Concurrently training SLP's provides accurate predictions of input objects and responses thereto and enhances the network by providing high quality value predictions and responses and avoiding potential training and operational delays.

Abstract: Methods for prophylactic treatment of hemophilia B are provided in which modified FIX polypeptides, particularly FIXa, are subcutaneously administered daily or less frequently, such as every other day, or every 2, 3 or 4 days. The treatment results in normal coagulation pharmacokinetics and normal levels of FIX, or mild hemophilia B.

Abstract: An inorganic substrate with an improved via shape and methods for facilitating formation of such improved via shape are disclosed. A double-sided opening process may be applied to an inorganic substrate to form openings at the ends of a damage track previously formed in the inorganic substrate. One side of the inorganic substrate may then be sealed, such as by being temporarily bonded to a carrier or blocking substrate, so that a single-sided opening process may be applied to the other unsealed or unblocked surface of the inorganic substrate. The single-sided opening process may enlarge at least one of the openings formed by the double-sided opening process and may enlarge a channel between the openings to form a via having an advantageous shape.

Abstract: Processed inorganic wafers and processing a wafer stack including an abrasive process are disclosed. A wafer stack may be formed at least by performing a temporary bonding process to temporarily bond at least a first inorganic wafer to a first surface of a handle wafer. The handle wafer may include at least one inorganic wafer, and the temporary bonding process may include formation of an adhesion layer between the first inorganic wafer and the first surface of the handle wafer. The adhesion layer may include a vacuum deposited carbonaceous film with a thickness between 1 nm and 100 nm, inclusive. An abrasive process may be applied to at least part of the wafer stack, and the abrasive process may reduce a thickness of the first inorganic wafer of the wafer stack. The first inorganic wafer may be debonded from the handle wafer after applying the abrasive process.

Abstract: Provided herein are modified FVII polypetides, and modified FVIIa polypeptides, and methods of treatment of acute and episodic bleeding with modified FactorVIIa polypeptides. To effect treatment and use, in some embodiments, the modified polypeptides are subcutaneously administered to provide on-demand treatment. In some embodiments, the on-demand treatment is provided in a multiple dosing regimen over a twenty-four hour period. The subcutaneous administration of the modified polypeptides of the disclosure exhibit increased coagulant activity, potency, bioavailablilty and prolonged duration.

Abstract: An approach is provided in which a system writes a set of data into a register file entry that includes a first memory array and a second memory array. The register file entry also includes a set of first write ports corresponding to the first memory array and a set of second write ports corresponding to the second memory array. The system configures a selection bit based on determining that a selected one of the set of first write ports is utilized to store the set of data in the first memory array. In turn, the system reads the set of data out of the first memory array based on the configured selection bit.

Abstract: A supervised learning processing (SLP) system and non-transitory, computer program product provides cooperative operation of a network of supervised learning processors to concurrently distribute supervised learning processor training, generate predictions, and provide prediction driven responses to input objects, such as NL statements. The SLP system includes SLP stages that are distributed across multiple SLP subsystems. Concurrently training SLP's provides accurate predictions of input objects and responses thereto, the SLP system and non-transitory, computer program product enhance the network by providing high quality value predictions and responses and avoiding potential training and operational delays. The SLP system can enhance the network of SLP subsystems by providing flexibility to incorporate multiple SLP models into the network and train at least a proper subset of the SLP models while concurrently using the SLP system and non-transitory, computer program product in commercial operation.

Abstract: The disclosure herein provides methods, systems, and devices for measuring similarity of and generating recommendations for unique items. A recommendation system for generating recommendations of alternative unique items comprises an items information database, a penalty computation engine, a recommendation compilation engine, and one or more computers, wherein the penalty computation engine comprises a customizations filter, a condition filter, and a dissimilarity penalty calculator.

Abstract: A machine learning of response selection to structured data input enables a machine to flexibly and responsively actively engage with a response recipient through a device, such as any electronic device connected to a data network. A system of one or more computers can be configured to respond to structured language messages, such as a textual messages, received from user devices with one or more templates that have been ranked using predetermined criteria including a machine learning classification of a momentum of a structured language message using a machine learning model. The momentum classification is correlated with templates. A ranking engine ranks the selection of candidate response templates in accordance with ranking criteria, including the momentum classifications for the candidate response templates. A highest ranked candidate response template is selected to provide a response to the textual messages received from the user devices.

Abstract: Provided herein are modified FVII polypetides, and modified FVIIa polypeptides, and methods of treatment of acute and episodic bleeding with modified FactorVIIa polypeptides. To effect treatment and use, in some embodiments, the modified polypeptides are subcutaneously administered to provide on-demand treatment. In some embodiments, the on-demand treatment is provided in a multiple dosing regimen over a twenty-four hour period. The subcutaneous administration of the modified polypeptides of the disclosure exhibit increased coagulant activity, potency, bioavailablilty and prolonged duration.

Abstract: A machine learning of insight communication selection in response to a triggering event in which event data specific to a user is provided to a machine to flexibly and proactively engage with the user through a device, such as any electronic device connected to a data network. In at least one embodiment, an insight selection engine improves insight communication selection to the triggering event by initially filtering a library of insight templates to identify candidate templates that best respond to the event data. In at least one embodiment, the insight selection engine includes an insight ranking module that ranks the identified candidate insight templates to provide an insight communication to the device two proactively engage the user with the system. The insight ranking module learns by receiving feedback, such as a linked recipient action result signal.

Abstract: A machine learning of response selection to structured data input enables a machine to flexibly and responsively actively engage with a response recipient through a device, such as any electronic device connected to a data network. In at least one embodiment, the response selection module improves response selection to the structure data input by initially filtering a library of templates to identify candidate templates that best respond to the input. In at least one embodiment, the response selection module ranks the identified candidate templates to provide the response to the device. The response selection module learns by receiving feedback, such as a linked recipient action result signal.

Abstract: The disclosure herein provides systems, methods, and devices for generating recommendations of dynamic or unique items. A system for generating recommendations of unique items comprises a data collection engine, a scoring engine, a user penalty calculator, and a recommendation compilation engine, wherein the recommendation engine is configured to transmit to a user access point system a list of recommended alternative unique items predicted to be preferred by a user of the user access point system.

Abstract: Provided herein are modified FVII polypeptides, and modified FVIIa polypeptides, and methods of treatment of acute and episodic bleeding with modified FactorVIIa polypeptides. To effect treatment and use, in some embodiments, the modified polypeptides are subcutaneously administered to provide on-demand treatment. In some embodiments, the on-demand treatment is provided in a multiple dosing regimen over a twenty-four hour period. The subcutaneous administration of the modified polypeptides of the disclosure exhibit increased coagulant activity, potency, bioavailablilty and prolonged duration.

Abstract: The disclosure herein provides systems, methods, and devices for determining and displaying market relative positions and/or attributes of unique items. A visualization system for generating electronic visualizations of market-relative attributes of unique items comprises an item selection receiver, a visualization compilation engine, and a rendering engine.

Abstract: The disclosure herein provides methods, systems, and devices for measuring similarity of and generating recommendations for unique items. A recommendation system for generating recommendations of alternative unique items comprises an items information database, a penalty computation engine, a recommendation compilation engine, and one or more computers, wherein the penalty computation engine comprises a customizations filter, a condition filter, and a dissimilarity penalty calculator.