Patents by Inventor Howard M. SAAL

Howard M. SAAL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating craniosynostosis in a patient
    Patent number: 11400140
    Abstract: The disclosure features methods for treating craniosynostosis in a patient (e.g., a patient having hypophosphatasia (HPP) and exhibiting or likely to have increased intracranial pressure (ICP)) by administering a soluble alkaline phosphatase (sALP) to the patient, e.g., in combination with a cranial surgery, e.g., a cranial vault remodeling procedure.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: August 2, 2022
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Howard M. Saal, Timothy W. Vogel
  • Methods for treating tracheobronchomalacia
    Patent number: 11116821
    Abstract: The disclosure features methods for treating tracheobronchomalacia (TBM) in a patient having hypophosphatasia (HPP), such as an infant, by administering a soluble alkaline phosphatase (sALP) to the patient.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: September 14, 2021
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventor: Howard M. Saal
  • METHODS FOR TREATING TRACHEOBRONCHOMALACIA
    Publication number: 20190209661
    Abstract: The disclosure features methods for treating tracheobronchomalacia (TBM) in a patient having hypophosphatasia (HPP), such as an infant, by administering a soluble alkaline phosphatase (sALP) to the patient.
    Type: Application
    Filed: August 18, 2017
    Publication date: July 11, 2019
    Inventor: Howard M. SAAL
  • METHODS FOR TREATING CRANIOSYNOSTOSIS IN A PATIENT
    Publication number: 20180326017
    Abstract: The disclosure features methods for treating craniosynostosis in a patient (e.g., a patient having hypophosphatasia (HPP) and exhibiting or likely to have increased intracranial pressure (ICP)) by administering a soluble alkaline phosphatase (sALP) to the patient, e.g., in combination with a cranial surgery, e.g., a cranial vault remodeling procedure.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 15, 2018
    Inventors: Howard M. SAAL, Timothy W. VOGEL