Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: Provided herein are systems for pressurized water storage, comprising: a water barrel having at least 3 fittings attached to it, wherein the first fitting is located towards the middle of the water barrel and adapted for sequentially attaching to a pressure gauge and/or valve and a municipal water supply, the second fitting is located towards the bottom of the water barrel and adapted for attaching to a hose bibb valve, and the third fitting is located on the top of the water barrel and adapted for attaching a pressure relief valve. Also provided herein are methods of using the same.

Abstract: A computer implemented method of displaying a virtual patient chart. The method includes receiving data relating to a patient and generating, using a processor, a graphic representing at least one attribute related to a characteristic of the patient, wherein the generating uses a plurality of consistent visual modification rules that convey additional information to the graphic. The method also includes displaying the graphic on a virtual patient chart.

Abstract: A computer implemented method of displaying a virtual patient chart. The method includes receiving data relating to a patient and generating, using a processor, a graphic representing at least one attribute related to a characteristic of the patient, wherein the generating uses a plurality of consistent visual modification rules that convey additional information to the graphic. The method also includes displaying the graphic on a virtual patient chart.

Abstract: A computer implemented method of displaying a virtual patient chart. The method includes receiving data relating to a patient and generating, using a processor, a graphic representing at least one attribute related to a characteristic of the patient, wherein the generating uses a plurality of consistent visual modification rules that convey additional information to the graphic. The method also includes displaying the graphic on a virtual patient chart.

Abstract: A computer implemented method of displaying a virtual patient chart. The method includes receiving data relating to a patient and generating, using a processor, a graphic representing at least one attribute related to a characteristic of the patient, wherein the generating uses a plurality of consistent visual modification rules that convey additional information to the graphic. The method also includes displaying the graphic on a virtual patient chart.

Abstract: A method for making a manifold for a tube and fin type heat exchanger is disclosed wherein the manifold includes a solder strip. The manifold includes a channel having a base member and a pair of vertical walls, a plurality of fluid conducting passageways in the base member, and a solder strip disposed in the channel. The strip is secured in place by bending a portion of the wall over a longitudinal edge of the solder strip.