Patents by Inventor Howard R. Six

Howard R. Six has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040185055
    Abstract: Transcutaneous immunostimulation administers at least one adjuvant by transcutaneous immunization to a subject who has undergone, is undergoing, or will undergo conventional vaccination. A subject is selected for treatment to stimulate the immune response to a conventional vaccine.
    Type: Application
    Filed: May 13, 2004
    Publication date: September 23, 2004
    Inventors: Gregory M Glenn, Howard R Six
  • Patent number: 5464630
    Abstract: The antibody response to a target antigen may be enhanced by incorporating the antigen into a liposome along with an additional constituent which contains at least one T-helper lymphocyte recognition site. The liposomes can include a wide variety of lipid materials. Both the antigen and the T-helper lymphocite recognition site containing constituent may be associated with the liposome by using hydrophobic interactions or by covalent attachment to a lipid.
    Type: Grant
    Filed: January 30, 1995
    Date of Patent: November 7, 1995
    Assignee: Research Development Foundation
    Inventors: Howard R. Six, Nathalie B. Garcon
  • Patent number: 5049388
    Abstract: Disclosed are aqueous aerosol droplets containing liposome or interacted liposome-drug or medication combination particles in a continuous phase of air or oxygen-enriched air advantageous for the treatment of a wide variety of diseases. The drug or medication is interacted with the liposome membrane so that on its rupture the drug or medication is not lost from the liposome. Different methods of preparation of the aerosol particles containing the liposome and interacted liposome-drug combination particles are described which can be used in small particle aerosol treatment. The majority of the aerosol droplets containing the liposome particles alone or with drugs has a diameter less than 5 microns and has an aerodynamic mass median diameter ranging from about 1 to 3 microns, and the liposome and interacted-liposome drug particles are substantially uniform in size and less than 1 micron in diameter.
    Type: Grant
    Filed: July 21, 1989
    Date of Patent: September 17, 1991
    Assignee: Research Development Foundation
    Inventors: Jack V. Knight, Brian E. Gilbert, Samuel Z. Wilson, Howard R. Six, Philip R. Wyde