Patents by Inventor Howard Root

Howard Root has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10456160
    Abstract: Assemblies and methods for scoring a stenotic region within a vessel of a patient are disclosed. An assembly can comprise a scoring member and a deployment member. The scoring member can include an elongate push structure and a tubular, self-expanding scaffold. The elongate push structure can be positioned proximal of the self-expanding scaffold and, at its distal end portion, eccentrically coupled with a proximal end portion of the self-expanding scaffold. The deployment member can be removably positioned within a central lumen of the self-expanding scaffold and detachably engageable with a portion of the self-expanding scaffold. The self-expanding scaffold can be movable between a downsized configuration, when receiving axial tension from the deployment member, and an expanded configuration, in the absence of axial tension.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: October 29, 2019
    Assignee: Teleflex Innovations S.à.r.l.
    Inventor: Howard Root
  • Patent number: 10377520
    Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: August 13, 2019
    Assignee: Teleflex Innovations S.A.R.L.
    Inventors: Howard Root, Stephen Anthony Penegor, James Arnold Murto
  • Publication number: 20190241300
    Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.
    Type: Application
    Filed: April 16, 2019
    Publication date: August 8, 2019
    Inventors: Howard Root, Stephen Anthony Penegor, James Arnold Murto
  • Patent number: 10159821
    Abstract: This patent document discloses perfusion catheters and related methods for treating complications related to CTO interventions or dilating a vessel occlusion while maintaining a passage through the treated vessel segment. A perfusion catheter can include a balloon formed of an inflatable tube and an elongate shaft having a lumen for providing inflation fluid to, or withdrawing inflation fluid from, the balloon. The inflatable tube can be coiled in a helical manner around a central axis into a series of windings. Adjacent windings can be stacked against and bonded to each other, and an inner surface of the series of windings, when inflated, can define the passage. The elongate shaft can be eccentrically attached to a proximal portion of the balloon and the shaft's lumen can be in fluid communication with the interior of the balloon, specifically the inflatable tube. The inflatable tube can include two different polymer tubes, one slightly smaller than the other.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: December 25, 2018
    Assignee: Teleflex Innovations S.à.r.l.
    Inventors: Howard Root, Chad Kugler, Dean Peterson, Joshua Brenizer
  • Patent number: 9968763
    Abstract: This patent document discloses perfusion catheters and related methods for treating complications related to CTO interventions or dilating a vessel occlusion while maintaining a passage through the treated vessel segment. A perfusion catheter can include a balloon formed of an inflatable tube and an elongate shaft having a lumen for providing inflation fluid to, or withdrawing inflation fluid from, the balloon. The inflatable tube can be coiled in a helical manner around a central axis into a series of windings. Adjacent windings can be stacked against and bonded to each other, and an inner surface of the series of windings, when inflated, can define the passage. The elongate shaft can be eccentrically attached to a proximal portion of the balloon and the shaft's lumen can be in fluid communication with the interior of the balloon, specifically the inflatable tube. The inflatable tube can include two different polymer tubes, one slightly smaller than the other.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: May 15, 2018
    Assignee: Teleflex Innovations S.à.r.l.
    Inventors: Howard Root, Chad Kugler, Dean Peterson, Joshua Brenizer
  • Patent number: 9782561
    Abstract: Catheters and related methods for supporting a guidewire or delivering an agent through a vessel stenosis or other tortuous anatomy are disclosed. A catheter can comprise an elongate shaft body and a polymer tip member disposed at a distal end of the shaft body. The shaft body and the tip member can include a liner, one or both of a braid member or a coil member surrounding the liner, and a polymer cover surrounding the braid member or the coil member. The tip member can further include one or more filaments extending from a position overlapping, underlapping, or abutting a distal end of the braid member or the coil member on their proximal ends to a position distal to the braid member or the coil member on their distal ends. The one or more filaments can include a plurality of filaments arranged in a series of contacting helical windings about the liner, the braid member, or the coil member.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: October 10, 2017
    Assignee: Vacular Solutions, Inc.
    Inventors: Chad Kugler, John Bridgeman, Derek Stratton, Steve Michael, Howard Root
  • Publication number: 20170143355
    Abstract: This patent document discloses assemblies, alignment devices and methods for creating a bi-directional path through an occlusion. An alignment device can include a positioning member and a tubular member. The tubular member can be coupled with a distal end portion of the positioning member and can include proximal and distal progressive size-changing shapes separated by a narrow neck passageway. An assembly can include the alignment device, a guide catheter having a lumen in which the alignment device is at least partially positioned, a guidewire, and a specialty catheter for supporting the guidewire. The alignment device and the guide catheter can be advanced in an antegrade direction to a proximal end of the occlusion, and the guidewire and the specialty catheter can be advanced in a retrograde direction to a distal end of the occlusion. The guidewire and the specialty catheter can be manipulated through the occlusion and into the distal end of the tubular member.
    Type: Application
    Filed: September 1, 2016
    Publication date: May 25, 2017
    Inventors: William Nicholson, Chad Kugler, Joshua Brenizer, Howard Root
  • Publication number: 20170113824
    Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.
    Type: Application
    Filed: January 5, 2017
    Publication date: April 27, 2017
    Inventors: Howard Root, Stephen Anthony Penegor, James Arnold Murto
  • Publication number: 20170050003
    Abstract: This patent document discloses perfusion catheters and related methods for treating complications related to CTO interventions or dilating a vessel occlusion while maintaining a passage through the treated vessel segment. A perfusion catheter can include a balloon formed of an inflatable tube and an elongate shaft having a lumen for providing inflation fluid to, or withdrawing inflation fluid from, the balloon. The inflatable tube can be coiled in a helical manner around a central axis into a series of windings. Adjacent windings can be stacked against and bonded to each other, and an inner surface of the series of windings, when inflated, can define the passage. The elongate shaft can be eccentrically attached to a proximal portion of the balloon and the shaft's lumen can be in fluid communication with the interior of the balloon, specifically the inflatable tube. The inflatable tube can include two different polymer tubes, one slightly smaller than the other.
    Type: Application
    Filed: October 18, 2016
    Publication date: February 23, 2017
    Inventors: Howard Root, Chad Kugler, Dean Peterson, Joshua Brenizer
  • Publication number: 20170043139
    Abstract: Fluid delivery or removal systems and methods for use during a medical procedure are disclosed. A system can include a base member, a receptacle configured to be received by a chamber of the base member, and a pressure sensor. The base member can include a piston having the pressure sensor positioned at or near its tip, a powered actuator for imparting motive forces to the piston, and a rechargeable power supply to energize the actuator. The receptacle is configured to contain a volume of fluid partially retained by a seal member. A surface of the seal member opposite the fluid can include a cavity to receive and engage the piston's tip when the receptacle is placed in the chamber. Based on a user-defined parameter input (e.g., a desired pressure set point) received by the system, the piston can be driven in an axial direction by the powered actuator, thereby urging an amount of fluid through a distal opening in the receptacle.
    Type: Application
    Filed: May 3, 2016
    Publication date: February 16, 2017
    Inventor: Howard Root
  • Patent number: 9561893
    Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: February 7, 2017
    Assignee: Vascular Solutions, Inc.
    Inventors: Howard Root, Stephen Anthony Penegor, James Arnold Murto
  • Patent number: 9522253
    Abstract: Catheter assemblies, kits and methods allowing for the drainage or administration of fluid or small particles are disclosed. A catheter assembly can include a shaft with a lumen, an expandable retention member, an elongate actuation member and a locking mechanism. The expandable retention member can be positioned at a shaft distal end portion and can include one or more filaments forming a plurality of drainage or administration interstices of variable or uniform size. The elongate actuation member can include an actuation member distal end, directly or indirectly engaged with the expandable retention member, and an actuation member proximal end. Movement of the actuation member proximal end relative to a proximal end of the shaft can cause the expandable retention member to change from a lower-profile configuration to a higher-profile configuration. A moved position of the elongate actuation member can be secured by rotating, sliding or otherwise manipulating the locking mechanism.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: December 20, 2016
    Assignees: Vascular Solutions, Inc.
    Inventors: Eric Gandras, Howard Root, Dean Peterson
  • Publication number: 20160262789
    Abstract: Assemblies and methods for scoring a stenotic region within a vessel of a patient are disclosed. An assembly can comprise a scoring member and a deployment member. The scoring member can include an elongate push structure and a tubular, self-expanding scaffold. The elongate push structure can be positioned proximal of the self-expanding scaffold and, at its distal end portion, eccentrically coupled with a proximal end portion of the self-expanding scaffold. The deployment member can be removably positioned within a central lumen of the self-expanding scaffold and detachably engageable with a portion of the self-expanding scaffold. The self-expanding scaffold can be movable between a downsized configuration, when receiving axial tension from the deployment member, and an expanded configuration, in the absence of axial tension.
    Type: Application
    Filed: January 8, 2016
    Publication date: September 15, 2016
    Inventor: Howard Root
  • Patent number: 9351736
    Abstract: Assemblies, kits, and methods for occluding a vascular vessel, such as a varicose vein, are disclosed. An assembly can include a removable inner member, a removable outer member, and an elongated expandable member positioned in a compressed form between portions of the inner and outer members. To facilitate their removal, one or both of the inner and outer members can include a handle coupled to a proximal end. The elongated expandable member can include a gelatin material or a collagen material that is configured, when wetted, to expand from a compressed first diametrical size to a second larger diametrical size within a time period of 5 minutes or less. At the second larger diametrical size, the gelatin or collagen material can occlude a vascular vessel for a period of at least 20 days without degrading.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: May 31, 2016
    Assignee: Vascular Solutions, Inc.
    Inventors: Howard Root, James Arnold Murto, Stephen Anthony Penegor, Gregg Sutton
  • Publication number: 20160101261
    Abstract: Catheters and related methods for supporting a guidewire or delivering an agent through a vessel stenosis or other tortuous anatomy are disclosed. A catheter can comprise an elongate shaft body and a polymer tip member disposed at a distal end of the shaft body. The shaft body and the tip member can include a liner, one or both of a braid member or a coil member surrounding the liner, and a polymer cover surrounding the braid member or the coil member. The tip member can further include one or more filaments extending from a position overlapping, underlapping, or abutting a distal end of the braid member or the coil member on their proximal ends to a position distal to the braid member or the coil member on their distal ends. The one or more filaments can include a plurality of filaments arranged in a series of contacting helical windings about the liner, the braid member, or the coil member.
    Type: Application
    Filed: September 22, 2015
    Publication date: April 14, 2016
    Inventors: Chad Kugler, John Bridgeman, Derek Stratton, Steve Michael, Howard Root
  • Publication number: 20160066932
    Abstract: This patent document discloses perfusion catheters and related methods for treating complications related to CTO interventions or dilating a vessel occlusion while maintaining a passage through the treated vessel segment. A perfusion catheter can include a balloon formed of an inflatable tube and an elongate shaft having a lumen for providing inflation fluid to, or withdrawing inflation fluid from, the balloon. The inflatable tube can be coiled in a helical manner around a central axis into a series of windings. Adjacent windings can be stacked against and bonded to each other, and an inner surface of the series of windings, when inflated, can define the passage. The elongate shaft can be eccentrically attached to a proximal portion of the balloon and the shaft's lumen can be in fluid communication with the interior of the balloon, specifically the inflatable tube. The inflatable tube can include two different polymer tubes, one slightly smaller than the other.
    Type: Application
    Filed: September 10, 2015
    Publication date: March 10, 2016
    Inventors: Howard Root, Chad Kugler, Dean Peterson, Joshua Brenizer
  • Publication number: 20150297875
    Abstract: Vascular dilator systems, kits, and methods allowing for sheathless introduction of a treatment device into a body vessel or body cavity are disclosed. A vascular dilator system can include a dilator assembly, including a tubular shaft and a deformable member, and optionally, the treatment device. The deformable member can include a non-biodegradable material and can have a diameter at a proximal end portion that is greater than a diameter at a distal end portion. The distal end portion of the deformable member can be coupled to an outer surface of the tubular shaft, at or near a shaft distal end portion. The proximal end portion of the deformable member can include a diameter configured to receive or stretch around a distal end portion of the treatment device. In use, the deformable member can provide a tapered bridge between the outer surface of the tubular shaft and an outer surface of the treatment device.
    Type: Application
    Filed: June 10, 2015
    Publication date: October 22, 2015
    Inventors: Doug Fraser, Howard Root, Thomas Holman, Deepa Deepa
  • Publication number: 20150265310
    Abstract: Vascular introducer systems, kits, and methods providing or creating access to vessels, such as radial or femoral arteries, are disclosed. A vascular introducer system includes a removable inner tubular member, a removable outer tubular, tear-away member, and an expandable passage member positioned between the inner and outer tubular members. The removable inner tubular member and the removable outer tubular, tear-away member help protect and maintain a contracted configuration of the expandable passage member when the introducer system is advanced into a vessel. The expandable passage member includes an inner surface configured to receive an elongate treatment device, for example, following removal of the inner and outer tubular members. In some examples, the expandable passage member includes one or more kink-resistant members extending along a portion of the passage member.
    Type: Application
    Filed: June 9, 2015
    Publication date: September 24, 2015
    Inventors: Howard Root, Gregg Sutton
  • Publication number: 20150238196
    Abstract: Assemblies and methods for occluding a vascular vessel are disclosed. An assembly can include a removable outer member, an elongate expandable member, a porous cover member, and optionally, one or both of a removable inner tubular member or a seal member. The elongate expandable member and the porous cover member can be positioned in a radially compressed form between the removable outer members and, if present, the inner tubular member, with the porous cover member surrounding an outer surface of the elongate expandable member. The elongate expandable member can be configured to expand the porous cover member and occlude a vascular vessel following removal of the removable outer member. Mechanical stability and migration resistance of the elongate expandable member can be aided by the porous cover member. The seal member can be positioned at a distal end of the elongate expandable member to inhibit its expansion during vessel insertion.
    Type: Application
    Filed: February 24, 2015
    Publication date: August 27, 2015
    Inventors: Howard Root, James Arnold Murto, Stephen Anthony Penegor
  • Patent number: 9078991
    Abstract: Vascular dilator systems, kits, and methods allowing for sheathless introduction of a treatment device into a body vessel or body cavity are disclosed. A vascular dilator system can include a dilator assembly, including a tubular shaft and a deformable member, and optionally, the treatment device. The deformable member can include a non-biodegradable material and can have a diameter at a proximal end portion that is greater than a diameter at a distal end portion. The distal end portion of the deformable member can be coupled to an outer surface of the tubular shaft, at or near a shaft distal end portion. The proximal end portion of the deformable member can include a diameter configured to receive or stretch around a distal end portion of the treatment device. In use, the deformable member can provide a tapered bridge between the outer surface of the tubular shaft and an outer surface of the treatment device.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: July 14, 2015
    Assignee: Vascular Solutions, Inc.
    Inventors: Doug Fraser, Howard Root, Thomas Holman, Deepa Deepa