Abstract: Disclosed is an improved fish hook having a barb placed between the lower bend and the vertical climb of the shank. The positioning of the barb is strategically positioned a distance from the sharpened point thereby incurring the advantages of a barbless fish hook in combination with the advantages of a barbed fish hook.

Abstract: A method, computer program product, and system for generating a roadmap visualization for a set of topics, comprising collecting topic data about each topic in a set of topics from an entity, analyzing the collected topic data to calculate one or more business scores for each topic, generating a visualization by plotting entity datapoints for each topic in a visualization format, where visual characteristics of the entity datapoints indicate the business scores for each topic, and displaying the visualization on a display device. The topics may relate to information technology, human resources, risk, audit, capital planning, research and development, or any other entity-related topic desired to be visualized, and the business scores may be any suitable information desired to be visualized, such as risk scores, business impact scores, implementation scores, or alignment scores.

Abstract: N-Benzoyl arylsulfonamides having the formula are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.

Abstract: An apparatus and method for securing bait fish to a fishing hook. The apparatus is in the form of a kit and includes a bait hook attachment device and crimping pliers that provides a quick and convenient attachment point for securing to a fishing hook. The bait hook attachment device is formed from a preformed single piece of wire having two ends spaced apart and available for placement on each side of a bait. The attachment device is secured to the fish hook by crimping of wire by use of a matching crimping pliers. Upon securement of the hook assembly, an aperture is formed for use in attachment to a bait fish.

Abstract: Methods for identifying cancer patients eligible to receive Bcl-2 family inhibitor therapy and for monitoring patient response to Bcl-2 family inhibitor therapy comprise assessment of the expression levels of the biomarker combinations set out in TABLES 1, 2, 3, 4, 5 or 6 in a patient tissue sample. The methods of the invention allow more effective identification of patients to receive Bcl-2 family inhibitor therapy and of determination of patient response to the therapy.

Abstract: An apparatus and method for securing bait fish to a fishing hook. The apparatus is in the form of a kit and includes a bait hook attachment device and crimping pliers that provides a quick and convenient attachment point for securing to a fishing hook. The bait hook attachment device is formed from a preformed single piece of wire having two ends spaced apart and available for placement on each side of a bait. The attachment device is secured to the fish hook by crimping of wire by use of a matching crimping pliers. Upon securement of the hook assembly, an aperture is formed for use in attachment to a bait fish.

Abstract: An apparatus and method of attaching a flexible line to a fixed object by use of an improved attachment shank with angled and spaced apart attachment coils. The attachment shank is based upon a one piece shank having at least three angled and spaced apart coils, along with an end coil, formed at one end of the shank with the other end of the shank typically forming a hook, clasp, or the like. The spaces disposed between the angled coils allow for windable insertion of the open end of a loop of fishing line between the spaces. The closed end of the loop extends towards the hooked end and a strand of the loop is wrapped around the shank at least four times. The line extend from the coils and the hook are then pulled in opposite directions which pulls the wound line taunt about the shank and angled coils. The line is thereby tightly secured to the shank through frictional engagement which increases with tension, yet does not unnecessarily bend or bind the attached line.

Abstract: Disclosed is a method for attaching a flexible line to a fixed object by use of an improved attachment shank. The attachment shank is based upon a one piece shank having at least three circular bends formed at one end of the shank, the free end of the shank forming a hook, clasp, or the like shape. The circular bends of the shank form a centrally disposed aperture set in a parallel plane to a centerline of the shank. Attachment of a flexible line to the shank is performed by inserting the flexible line through the aperture and reinserting a portion of the flexible line through the opposite end of the aperture. The flexible line is then twisted into at least three predefined loops engaging the circumference of the shank. Upon pulling of the line, the loops are pulled taunt about the shank tightly securing the line to the shank using the aperture as a slide preventing shoulder.