Patents by Inventor Howard Sauls

Howard Sauls has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGH THROUGHPUT METHOD FOR SCREENING CANDIDATE COMPOUNDS FOR BIOLOGICAL ACTIVITY
    Publication number: 20080009019
    Abstract: A method for screening candidate compounds for an ability to modulate the biological activity of a target. The method includes the steps of providing a substrate comprising a target and an indicator, the substrate adapted for receiving a plurality of candidate compounds; contacting the substrate with a plurality of candidate compound samples in a manner wherein an identity of each candidate compound can be determined and wherein the candidate compounds in the candidate compound samples interact with the target in the substrate; detecting a signal, the signal produced by the indicator upon interaction between the target and a candidate compound; and identifying a candidate compound as a modulator of the biological activity of the target based upon an amount of signal produced.
    Type: Application
    Filed: January 17, 2007
    Publication date: January 10, 2008
    Applicant: SmithKline Beecham Corporation
    Inventors: Jill Haizlip, Diane Ignar, Channa Jayawickreme, Holly King, James Liacos, Kirsten Mills, Jason Ruan, Howard Sauls, Joel Shaffer
  • Method of screening for gpr40 ligands
    Publication number: 20040137517
    Abstract: Methods of screening for ligands of the GPR40 receptor are provided, including methods utilizing fatty acid GPR40 ligands.
    Type: Application
    Filed: June 18, 2003
    Publication date: July 15, 2004
    Inventors: John Leon Andrews, Celia Patricia Briscoe, Diane Michele Ignar, Alison Isobel Muir, Howard Sauls, Mohammad Tadayyon