Patents by Inventor Howard Simons

Howard Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210139418
    Abstract: The present invention describes methods of preparing a cell composition for treating cancer in a human being by obtaining lymphocytes from a partially or fully HLA-matched healthy donor, activating and expanding T cells reactive to neo-antigens (i.e. new epitopes resulting from somatic mutations in the cancer cell), and enriching for tumor-specific T cells that are not reactive against non-tumor tissue of the cancer patient. Provide herein are lymphocyte compositions comprising partially or fully HLA-matched healthy donor T cells reactive to neo-antigens. Also provided herein are methods of treating human cancer with such neo-antigen-specific, non-alloreactive T cells.
    Type: Application
    Filed: November 20, 2020
    Publication date: May 13, 2021
    Inventors: Ephraim J. Fuchs, Howard Simons
  • Publication number: 20180265456
    Abstract: Resins are provided including bisphenol M diphthalonitrile ether resin or bisphenol P diphthalonitrile either resin. Compositions are also provided, including a primary amine curative and the bisphenol M diphthalonitrile ether resin or the bisphenol P diphthalonitrile either resin. Further, polymerized products are provided of the bisphenol M diphthalonitrile ether resin or the bisphenol P diphthalonitrile either resin. In addition, a method of making a polymerized network is provided. A two component system is further provided, including a curative in one of the components and the bisphenol M diphthalonitrile ether resin or the bisphenol P diphthalonitrile either resin in the other component. In addition, a resin blend is provided, including a blend of at least two of bisphenol M diphthalonitrile ether resin, bisphenol P diphthalonitrile either resin, or bisphenol T diphthalonitrile ether resin.
    Type: Application
    Filed: March 24, 2017
    Publication date: September 20, 2018
    Applicant: The John Hopkins University
    Inventors: Ephraim J. Fuchs, Howard Simons
  • Publication number: 20160075358
    Abstract: A collapsible trolley includes a frame, a carrier plate, two wheel units, a primary grip and two auxiliary grip units. The frame includes two lower tubes and two upper tubes each pivotally connected to a corresponding one of the lower tubes. The carrier plate is connected to the lower tubes. Each of the wheel units is connected to a corresponding one of the lower tubes. The primary grip is supported on the upper tubes. Each of the auxiliary grip units is pivotally connected to a corresponding one of the upper tubes.
    Type: Application
    Filed: September 15, 2014
    Publication date: March 17, 2016
    Inventors: Howard Simon, Wen Tung Chang
  • Patent number: 7962391
    Abstract: A system and method for determining eligibility of persons and enrolling those persons in various programs. For example, one embodiment is particularly suited for enrolling credit card members in payment programs. A program is selected, after which enrollment information is entered. The enrollment information is checked and verified, and the enrollment application is checked for eligibility. The enrollment may be either accepted or declined. The possibility of reiterative enrollment in more than one program is provided. A system is provided for tracking which payment programs are the most enticing for later feedback analysis.
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: June 14, 2011
    Assignee: JPMorgan Chase Bank, N.A.
    Inventors: Scott Howard Simon, Nancy W. Woodall, Michael F. Nikithser, Jon K. Forst, Gregory Shields
  • Publication number: 20090235633
    Abstract: An integrated power plant comprising a gas turbine set with a compressor, a combustion chamber and a gas turbine, a waste heat recovery unit (WHRU) arranged downstream of the gas turbine, the heat from the gas turbine flue gases being recovered directly in the WHRU in a coil fed by hydrocarbons or other process fluid. The resulting two-phase hydrocarbon or process stream leaving the WHRU is separated into a vapour and liquid stream using a Fractionating Auxiliary Treatment (FAT) system.
    Type: Application
    Filed: September 9, 2005
    Publication date: September 24, 2009
    Inventor: Howard Simons
  • Patent number: 7467109
    Abstract: A system and method for determining eligibility of persons and enrolling those persons in various programs. For example, one embodiment is particularly suited for enrolling credit card members in payment programs. A program is selected, after which enrollment information is entered. The enrollment information is checked and verified, and the enrollment application is checked for eligibility. The enrollment may be either accepted or declined. The possibility of reiterative enrollment in more than one program is provided. A system is provided for tracking which payment programs are the most enticing for later feedback analysis.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: December 16, 2008
    Assignee: JPMorgan Chase Bank, N.A.
    Inventors: Scott Howard Simon, Nancy W. Woodall, Michael F. Nikithser, Jon K. Forst, Gregory Shields
  • Publication number: 20080033863
    Abstract: A method for establishing a credit default swap index on a defined economic sector. A reference economic sector is identified by an index provider. A multi-credit corporate index is established for the reference economic sector. Individual credit default swap (CDS) transactions and the multi-credit corporate index are used to compile an industry sector CDS index for the reference economic sector. At least one issue or credit reference in the industry sector CDS index is weighted differently, relative to the weight of other issues or credit references in the industry sector CDS index. Structured credit instruments are issued by a dealer based on the industry sector CDS sector index. Trading positions with respect to the structured credit instruments are monitored by a dealer. The structured credit instruments are settled against the industry sector CDS index.
    Type: Application
    Filed: December 22, 2006
    Publication date: February 7, 2008
    Inventors: Howard Simons, Bradley McGill, Daniel Sanabria