Patents by Inventor Howing LEE

Howing LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140272976
    Abstract: The present invention relates to methods for screening for binding interactions using multiple sets of microparticles, wherein said set has the same identifiable characteristic and wherein one of more sets comprise subsets of microparticles and said subset presents at least one unique probe that acts as a binding partner for a target molecule in a biological sample. In particular, the invention provides for methods of detecting tissue-typing antigens in donor tissue or recipient tissue using these multiple sets of microparticles.
    Type: Application
    Filed: June 2, 2014
    Publication date: September 18, 2014
    Applicant: ONE LAMBDA
    Inventors: Jar-How Lee, Terrence Chen, Thoa Nong
  • Patent number: 8803586
    Abstract: A frequency mixer circuit includes a gain stage and a mixer. The gain stage has a specific circuit design to convert a differential input voltage signal into a differential current signal with an input frequency. The mixer receives a differential local oscillator (LO) voltage signal with a LO frequency, and the differential current signal from the gain stage, and outputs a differential output voltage signal having a mixed frequency associated with the input frequency and the LO frequency.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: August 12, 2014
    Assignee: National Chi Nan University
    Inventors: Jen-How Lee, Yo-Sheng Lin, Wei-Chen Wen
  • Publication number: 20140210354
    Abstract: A system includes an external light supply to a silicon photonic chip. The light supply includes a primary light source, a secondary light source, an optical coupler, an optical splitter, and a dark sensor. The optical coupler is to combine any output from the primary light source and any output from the secondary light source into an input to the silicon photonic chip. The optical splitter is located in an optical path between the primary light source and the optical coupler, and is to divert part of the output from the primary light source. The dark sensor is to receive the diverted part of the output from the primary light source and to selectively activate the secondary light source based on the diverted part of the output from the primary light source.
    Type: Application
    Filed: January 29, 2013
    Publication date: July 31, 2014
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Jing Kai Tan, Chee How Lee, Kian Teck Poh
  • Patent number: 8748090
    Abstract: The present invention relates to methods for screening for binding interactions using multiple sets of microparticles, wherein said set has the same identifiable characteristic and wherein one of more sets comprise subsets of microparticles and said subset presents at least one unique probe that acts as a binding partner for a target molecule in a biological sample. In particular, the invention provides for methods of detecting tissue-typing antigens in donor tissue or recipient tissue using these multiple sets of microparticles.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: June 10, 2014
    Assignee: One Lambda, Inc.
    Inventors: Jar-How Lee, Terrence Chen, Thoa Nong
  • Publication number: 20140099733
    Abstract: The invention is directed to methods of screening for HLA antibodies comprising detecting antibodies specific for native HLA antigens and denatured HLA antigens. The invention also provides for methods of removing antibodies specific for denatured HLA antigens or antibodies specific for native HLA antigens from a serum sample. In addition, the invention also provides for method of predicting whether a transplant recipient has an increased risk for rejecting the transplanted organ.
    Type: Application
    Filed: December 11, 2013
    Publication date: April 10, 2014
    Applicant: One Lambda
    Inventors: Jar-How Lee, Rui Pei, Thao Nong
  • Publication number: 20140065846
    Abstract: In one implementation a device connector includes a first electronic device magnet, second electronic device magnet, and third electronic device magnet to connect to a power supply. The power supply magnet can be oriented to the opposite pole of one of the electronic device magnets.
    Type: Application
    Filed: August 29, 2012
    Publication date: March 6, 2014
    Inventors: Kian Teck Poh, Chee How Lee, Jing Kai Tan
  • Patent number: 8628932
    Abstract: The invention is directed to methods of screening for HLA antibodies comprising detecting antibodies specific for native HLA antigens and denatured HLA antigens. The invention also provides for methods of removing antibodies specific for denatured HLA antigens or antibodies specific for native HLA antigens from a serum sample. In addition, the invention also provides for method of predicting whether a transplant recipient has an increased risk for rejecting the transplanted organ.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: January 14, 2014
    Assignee: One Lambda
    Inventors: Jar-How Lee, Rui Pei, Thoa Nong
  • Publication number: 20130330725
    Abstract: The invention provides methods for detecting target nucleic acid sequences with diagnostic probes including first and second probe regions that are substantially complementary to first and second target regions respectively on a target nucleic acid strand wherein the first probe region is located 5? to the second probe region. The first probe region is substantially complementary to the first target region, on the target nucleic acid strand, which also includes a second target region, wherein when said first target region is contiguous with the second target region on the target nucleic acid strand, then the first and second probe regions on the diagnostic probe are separated by a spacer region of nucleic acid.
    Type: Application
    Filed: August 14, 2013
    Publication date: December 12, 2013
    Applicant: ONE LAMBDA
    Inventors: Katsuyuki Saito, Jar-How Lee, Lindley Blair
  • Patent number: 8512953
    Abstract: The invention provides methods for detecting target nucleic acid sequences with diagnostic probes including first and second probe regions that are substantially complementary to first and second target regions respectively on a target nucleic acid strand wherein the first probe region is located 5? to the second probe region. The first probe region is substantially complementary to the first target region, on the target nucleic acid strand, which also includes a second target region, wherein when said first target region is contiguous with the second target region on the target nucleic acid strand, then the first and second probe regions on the diagnostic probe are separated by a spacer region of nucleic acid.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: August 20, 2013
    Assignee: One Lambda
    Inventors: Katsuyuki Saito, Jar-How Lee, Lindley Blair
  • Publication number: 20120066423
    Abstract: A master node selects a plurality of slave nodes that share a common slave address to receive a data communication. The master node multicasts the data communication to the plurality of selected slave nodes via an inter-integrated circuit bus having a serial data line and a serial clock line.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 15, 2012
    Inventors: Boon Siang Choo, Tzye Perng Poh, Chee How Lee
  • Publication number: 20110250619
    Abstract: The invention is directed to methods of screening for HLA antibodies comprising detecting antibodies specific for native HLA antigens and denatured HLA antigens. The invention also provides for methods of removing antibodies specific for denatured HLA antigens or antibodies specific for native HLA antigens from a serum sample. In addition, the invention also provides for method of predicting whether a transplant recipient has an increased risk for rejecting the transplanted organ.
    Type: Application
    Filed: March 9, 2011
    Publication date: October 13, 2011
    Applicant: ONE LAMBDA
    Inventors: Jar-How Lee, Rui Pei, Thoa Nong
  • Patent number: 7972804
    Abstract: The invention is directed to methods of screening for HLA antibodies comprising detecting antibodies specific for native HLA antigens and denatured HLA antigens. The invention also provides for method of predicting whether a transplant recipient has an increased risk for rejecting the transplanted organ.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: July 5, 2011
    Assignee: One Lambda
    Inventors: Jar-How Lee, Rui Pei, Thoa Nong
  • Publication number: 20100158163
    Abstract: A method for estimating the velocity of the Mobile Station (MS) in Orthogonal Frequency Divisional Multiplexing (OFDM)/Orthogonal Frequency Divisional Multiplexing Access (OFDMA) system is disclosed. First, the pilots in the preamble are received by MS and the pilots in a specified symbol of the specific zone are received by MS. An auto-correlation between the received pilots in preamble and the received pilots in the specified symbol of the specific zone is calculated. The auto-correlation is the calculated with frame by frame basis, and the average auto-correlation is calculated from number of frames. Once the average auto-correlation is obtained, the velocity of MS is estimated from predetermined function according to the obtained average auto-correction.
    Type: Application
    Filed: December 22, 2008
    Publication date: June 24, 2010
    Inventors: Kuo-Ming Wu, Wen-How Lee
  • Publication number: 20090142762
    Abstract: The present invention relates to methods for screening for binding interactions using multiple sets of microparticles, wherein said set has the same identifiable characteristic and wherein one of more sets comprise subsets of microparticles and said subset presents at least one unique probe that acts as a binding partner for a target molecule in a biological sample. In particular, the invention provides for methods of detecting tissue-typing antigens in donor tissue or recipient tissue using these multiple sets of microparticles.
    Type: Application
    Filed: May 2, 2008
    Publication date: June 4, 2009
    Applicant: ONE LAMBDA, INC.
    Inventors: Jar-How Lee, Terrence Chen, Thoa Nong
  • Publication number: 20090011437
    Abstract: The invention is directed to methods of screening for HLA antibodies comprising detecting antibodies specific for native HLA antigens and denatured HLA antigens. The invention also provides for method of predicting whether a transplant recipient has an increased risk for rejecting the transplanted organ.
    Type: Application
    Filed: June 27, 2008
    Publication date: January 8, 2009
    Applicant: ONE LAMBDA
    Inventors: Jar-How Lee, Rui Pei, Thoa Nong
  • Patent number: 6737621
    Abstract: A microwave oven having a high voltage control circuit which prevents an overheating of a high voltage transformer. The high voltage control circuit includes a thermostat which is turned on or off according to a temperature of the high voltage transformer. The thermostat is disposed between a first fixed terminal of a tap formed at a primary coil of the high voltage transformer and a second fixed terminal connected to a power stage, so as to allow the primary coil to have different numbers of turns. According, where the output of a magnetron of the microwave oven becomes high and the temperature of the high voltage transformer reaches a predetermined temperature, the thermostat is turned off, thus enabling the first and second fixed terminals to be disconnected from each other.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: May 18, 2004
    Assignee: Samsung Electronics Co., LTD
    Inventor: Chea-How Lee
  • Publication number: 20040004076
    Abstract: A microwave oven having a high voltage control circuit which prevents an overheating of a high voltage transformer. The high voltage control circuit includes a thermostat which is turned on or off according to a temperature of the high voltage transformer. The thermostat is disposed between a first fixed terminal of a tap formed at a primary coil of the high voltage transformer and a second fixed terminal connected to a power stage, so as to allow the primary coil to have different numbers of turns. According, where the output of a magnetron of the microwave oven becomes high and the temperature of the high voltage transformer reaches a predetermined temperature, the thermostat is turned off, thus enabling the first and second fixed terminals to be disconnected from each other.
    Type: Application
    Filed: October 25, 2002
    Publication date: January 8, 2004
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Chea-How Lee
  • Publication number: 20030165925
    Abstract: The invention provides methods for detecting target nucleic acid sequences with diagnostic probes including first and second probe regions that are substantially complementary to first and second target regions respectively on a target nucleic acid strand wherein the first probe region is located 5′ to the second probe region. The first probe region is substantially complementary to the first target region, on the target nucleic acid strand, which also includes a second target region, wherein when said first target region is contiguous with the second target region on the target nucleic acid strand, then the first and second probe regions on the diagnostic probe are separated by a spacer region of nucleic acid.
    Type: Application
    Filed: September 24, 2002
    Publication date: September 4, 2003
    Inventors: Katsuyuki Saito, Jar-How Lee, Lindley Blair
  • Patent number: 6586716
    Abstract: A wall-mounted type microwave oven which carries out a sweeping operation of kitchen areas positioned therebelow, as well as cooking and exhaustion operations. The microwave oven includes an oven body for mounting in a kitchen area, having a cooking chamber and an electrical component compartment which are isolated from each other, an exhaust flow path which communicates between an intake port provided at a bottom panel of the oven body and an exhaust outlet provided at a top panel of the oven body to exhaust air existing under the oven body to the outside, an exhaust fan assembly provided at the exhaust outlet, a sweeping inlet provided at the bottom panel of the oven body, a sweeping flow path which is disposed in the oven body and communicates with an inlet of the exhaust fan assembly and the sweeping inlet, a filter assembly disposed in the sweeping flow path, and a sweeping hose detachably coupled to the sweeping inlet.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: July 1, 2003
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Chea-How Lee
  • Patent number: 6514714
    Abstract: The present invention provides an improved method for detection of panel reactive antibodies in serum of a subject against HLA class I antigens, which comprises the steps of adding serum from a subject to an array of microbeads, each microbead presenting HLA antigens from a cell population presenting the same HLA antigens; incubating the serum and microbeads for sufficient time for anti-HLA antibodies in the serum to bind to the HLA antigens presented on the microbeads; removing the serum components which do not specifically bind with the HLA antigens presented on the microbeads; incubating the microbeads with a labeled ligand capable of specifically binding with anti-HLA antibodies bound to said HLA antigens; removing the labeled ligand which is not bound to said HLA antigens; and detecting the presence of labeled ligand bound to said HLA antigens by flow cytometry.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: February 4, 2003
    Assignee: One Lambda
    Inventors: Jar-How Lee, Rui Pei