Abstract: A Neurological Rehabilitation method utilizing oculomotor, visual and/or vestibular rehabilitation tasks on subjects with pharmacologically induced neuroplasticity comprising the steps of Inducing neuroplasticity in a subject through administering of a neuroplasticity medicament; Providing a oculomotor, visual and vestibular rehabilitation task platform configured to supply visual targets to a subject for oculomotor, visual and vestibular rehabilitation tasks and track and record eye movement of the subject during oculomotor, visual and vestibular rehabilitation tasks; Performing oculomotor, visual and/or vestibular rehabilitation tasks on the platform with subjects during periods of pharmacologically induced neuroplasticity. The neuroplasticity medicament generally is comprising at least one of an antidepressant, a Brain Derived Neuro trophic factor enhancer, a steroid, a psychedelic, valproic acid, NDRI's, lithium carbonate, Metformin, N-Acetylcystine, and Human Growth Hormone.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: A head mounted compact goggle based video oculography system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

Abstract: A head mounted compact goggle based video oculography system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

Abstract: A head mounted compact goggle based video oculography system is configured for use in VOG-based neuro-otologic testing. The system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror within the goggle base; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

Abstract: In the field of eye tracking, greater accuracy or resolution in monitoring movement of the eye can be gained by digitizing the eye, and tracking the movement of a landmark with fixed size and a fixed location relative to the eye's local coordinate system. The edge of the iris can be used as such a fixed landmark. Through the location and or establishment of at least a portion of the outer edge of the iris and/or an iris center point, both large and small scale eye movements, including but not limited to micro-tremors, can be traced with a higher degree of accuracy. This will aid in the diagnosis of diseases, assessing state of consciousness, and defining brainstem death.

Abstract: A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.

Abstract: A head mounted compact goggle based video oculography system is configured for use in VOG-based neuro-otologic testing. The system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror within the goggle base; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.

Abstract: A method and associated apparatus for validating testing procedure in objective ophthalmic eye testing is implemented for eye evaluation applications requiring subject compliance with eye fixation to a visual target.

Abstract: A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: A goggle based light-weight VOG/EOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection. The EOG system is incorporated directly into a goggle base. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. The VOG system may track and record 3-D movement of the eye, track pupil dilation, head position and goggle slippage. An animated eye display provides data in a more meaningful fashion. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol including optokinetic testing that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol including optokinetic testing that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: A method and associated apparatus for validating testing procedure in objective ophthalmic eye testing is implemented for eye evaluation applications requiring subject compliance with eye fixation to a visual target.

Abstract: A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.