Patents by Inventor Hsi-Ya Huang

Hsi-Ya Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10538545
    Abstract: Disclosed herein are novel compounds of formula (I) and (II), each of which may serve as a reagent to deliver nitric oxide (NO) and a therapeutic agent to treat NO-associated diseases. Also disclosed are a pharmaceutical composition comprising the compound of formula (I) or (II), a composite material comprising the compound of formula (I) or (II), and the uses thereof.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: January 21, 2020
    Assignee: Chung Yuan Christian University
    Inventors: Tsai-Te Lu, Hsiao-Wen Huang, Chia-Her Lin, Yu-Ting Tseng, Wen-Feng Liaw, Hsi-Ya Huang, Show-Jen Chiou
  • Publication number: 20180208616
    Abstract: Disclosed herein are novel compounds of formula (I) and (II), each of which may serve as a reagent to deliver nitric oxide (NO) and a therapeutic agent to treat NO-associated diseases. Also disclosed are a pharmaceutical composition comprising the compound of formula (I) or (II), a composite material comprising the compound of formula (I) or (II), and the uses thereof.
    Type: Application
    Filed: January 24, 2017
    Publication date: July 26, 2018
    Applicant: Chung Yuan Christian University
    Inventors: Tsai-Te LU, Hsiao-Wen HUANG, Chia-Her LIN, Yu-Ting TSENG, Wen-Feng LIAW, Hsi-Ya HUANG, Show-Jen CHIOU
  • Patent number: 9421517
    Abstract: A metal-organic framework (MOF) polymer for solid-phase microextraction (SPME) includes an MOF including metal ions building units coordinating polytopic organic linkers; and a polymer coordinatively bonding to the MOF, wherein the polymer is composed of one or more vinyl monomers and a cross-linker those are polymerized in the presence of a radical initiator. A method for preparing a stationary phase for SPME is also provided.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: August 23, 2016
    Assignee: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Hsi-Ya Huang, Chia-Her Lin, Chen-Lan Lin, Yung-Han Shih, Stephen Lirio, Ya-Ting Chen
  • Publication number: 20160208047
    Abstract: A metal-organic framework (MOF) polymer for solid-phase microextraction (SPME) includes an MOF including metal ions building units coordinating polytopic organic linkers; and a polymer coordinatively bonding to the MOF, wherein the polymer is composed of one or more vinyl monomers and a cross-linker those are polymerized in the presence of a radical initiator. A method for preparing a stationary phase for SPME is also provided.
    Type: Application
    Filed: January 20, 2015
    Publication date: July 21, 2016
    Inventors: Hsi-Ya Huang, Chia-Her Lin, Chen-Lan Lin, Yung-Han Shih, Stephen Lirio, Ya-Ting Chen
  • Patent number: 9040273
    Abstract: A simple, highly efficient, and environmentally friendly method of immobilizing macromolecules, particularly the biomolecules, to a solid carrier and thus forming a bioreactor, including the following steps: (1) providing the biomolecule and a leading molecule, and linking the biomolecule and the leading molecule by microwave to form an adsorbent; (2) providing a porous support material, and mixing the porous support material and the adsorbent to form a mixture; (3) treating the mixture by a vortex process such that the adsorbent being adsorbed and immobilized on the porous support material to form a bioreactor for biological reactions and biocatalysis; and the bioreactor can be further used for constructing a biological reaction system via incorporating a buffer solution and a ligand.
    Type: Grant
    Filed: December 24, 2013
    Date of Patent: May 26, 2015
    Assignee: Chung Yuan Christian University
    Inventors: Hsi-Ya Huang, Wan-Ling Liu, Chia-Her Lin, Sheng-Han Lo, Tadena Brenda Singco, Chun-Chuen Yang
  • Publication number: 20140342429
    Abstract: A simple, highly efficient, and environmentally friendly method of immobilizing macromolecules, particularly the biomolecules, to a solid carrier and thus forming a bioreactor, including the following steps: (1) providing the biomolecule and a leading molecule, and linking the biomolecule and the leading molecule by microwave to form an adsorbent; (2) providing a porous support material, and mixing the porous support material and the adsorbent to form a mixture; (3) treating the mixture by a vortex process such that the adsorbent being adsorbed and immobilized on the porous support material to form a bioreactor for biological reactions and biocatalysis; and the bioreactor can be further used for constructing a biological reaction system via incorporating a buffer solution and a ligand.
    Type: Application
    Filed: December 24, 2013
    Publication date: November 20, 2014
    Applicant: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: HSI-YA HUANG, WAN-LING LIU, CHIA-HER LIN, SHENG-HAN LO, TADENA BRENDA SINGCO, CHUN-CHUEN YANG
  • Patent number: 8476335
    Abstract: The present invention relates to a method of manufacturing a polymer-based monolithic stationary phase in an ionic liquid reaction medium via microwave-assisted vinylization and polymerization. The invention is time-effective and environmental friendly for not using volatile organic compounds.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: July 2, 2013
    Assignee: Chung Yuan Christian University
    Inventors: Hsi-Ya Huang, Yung-Han Shih, Chao-Hsiang Hsu, Wan-Ling Liu, Singco Brenda
  • Publication number: 20130072593
    Abstract: The present invention relates to a method of manufacturing a polymer-based monolithic stationary phase in an ionic liquid reaction medium via microwave-assisted vinylization and polymerization. The invention is time-effective and environmental friendly for not using volatile organic compounds.
    Type: Application
    Filed: September 19, 2011
    Publication date: March 21, 2013
    Inventors: Hsi-Ya Huang, Yung-Han Shih, Chao-Hsiang Hsu, Wan-Ling Liu, Singco Brenda
  • Publication number: 20120184689
    Abstract: The present invention relates to a stationary phase composition. The composition comprises a support material, on which at least a divinylbenzene group and an acrylic group, and optionally a styrene group, are provided. Preferably, the acrylic group has an alkyl moiety of at least 4 carbon atoms. The composition can serve as a monolithic column for chromatographic separation. The composition exhibits an altered ?-? interaction with aromatic compounds, whereby the peak symmetry of aromatic compounds is improved during separation, the separation time is shortened and the occurrence of peak-overlapping and peak-tailing is prevented.
    Type: Application
    Filed: August 16, 2011
    Publication date: July 19, 2012
    Inventors: Hsi-Ya Huang, Yi-Jie Cheng, Chao-Hsiang Hsu, Wan-Ling Liu, Yi-Fen Hsu, Cheng-Lan Lin, Sze-Tsen Lee