Patents by Inventor Hsiao-Ling Chen

Hsiao-Ling Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11882846
    Abstract: The invention discloses that a kefir peptide with an amino acid sequence of SEQ ID No: 2 or a fermentation product comprising the kefir peptide has an antidepressant activity, which means that by administering an effective amount of the kefir peptide or a composition comprising an effective amount of the kefir peptide to an individual with depressive behaviors is capable of effectively improving or alleviating the individual's depressive behaviors. Since the kefir peptide disclosed in the invention is not a chemical compound, the kefir peptide will not have side effects on the human body even taking it on a long-term basis.
    Type: Grant
    Filed: November 26, 2021
    Date of Patent: January 30, 2024
    Assignee: NATIONAL CHUNG HSING UNIVERSITY
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Publication number: 20220346395
    Abstract: The invention discloses that a kefir peptide with an amino acid sequence of SEQ ID No: 2 or a fermentation product comprising the kefir peptide has an antidepressant activity, which means that by administering an effective amount of the kefir peptide or a composition comprising an effective amount of the kefir peptide to an individual with depressive behaviors is capable of effectively improving or alleviating the individual's depressive behaviors. Since the kefir peptide disclosed in the invention is not a chemical compound, the kefir peptide will not have side effects on the human body even taking it on a long-term basis.
    Type: Application
    Filed: November 26, 2021
    Publication date: November 3, 2022
    Inventors: Chuan-Mu CHEN, Hsiao-Ling CHEN
  • Patent number: 10829517
    Abstract: The present invention discloses a method for treating or/and preventing calcium deficiency-related diseases, which comprises administering a composition containing an effective amount of a peptide to a subject, wherein the peptide has an amino acid sequence as shown in SEQ ID NO. 3. The calcium ions are allowed to bind to the peptide and enter the cells of the patient, to achieve the effect of treating or/and preventing calcium deficiency-related diseases.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: November 10, 2020
    Assignee: NATIONAL CHUNG HSING UNIVERSITY
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Patent number: 10529994
    Abstract: A seawater battery includes an anode and a cathode corresponding to the anode. The cathode cooperates with the anode to produce a current and includes a metal substrate and a mixture coating layer. The mixture coating layer covered on the metal substrate includes a conductive polymer material and a plurality of carbon nanotubes mixed with the conductive polymer material.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: January 7, 2020
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Wen-Kuang Hsu, Hsiao-Ling Chen, Hsin-Jung Tsai
  • Publication number: 20190144502
    Abstract: The present invention discloses a method for treating or/and preventing calcium deficiency-related diseases, which comprises administering a composition containing an effective amount of a peptide to a subject, wherein the peptide has an amino acid sequence as shown in SEQ ID NO. 3. The calcium ions are allowed to bind to the peptide and enter the cells of the patient, to achieve the effect of treating or/and preventing calcium deficiency-related diseases.
    Type: Application
    Filed: November 14, 2018
    Publication date: May 16, 2019
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Publication number: 20170301927
    Abstract: A seawater battery includes an anode and a cathode corresponding to the anode. The cathode cooperates with the anode to produce a current and includes a metal substrate and a mixture coating layer. The mixture coating layer covered on the metal substrate includes a conductive polymer material and a plurality of carbon nanotubes mixed with the conductive polymer material.
    Type: Application
    Filed: August 2, 2016
    Publication date: October 19, 2017
    Inventors: Wen-Kuang HSU, Hsiao-Ling CHEN, Hsin-Jung TSAI
  • Patent number: 8974840
    Abstract: The present invention discloses a novel milk-fermented product comprising a group of peptides. The peptides are composed from no. 1 to no. 7 of the figure that is selected from the group consisting of FIG. 11 to FIG. 18. And the novel milk-fermented product is used for suppressing the reduction of bone mineral density. Therefore, the novel milk-fermented product could be a component of foods, nutrient supplement or medicine for treating or preventing osteoporosis.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: March 10, 2015
    Assignee: National Chung Hsing University
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Publication number: 20140378386
    Abstract: The present invention discloses a novel milk-fermented product comprising a group of peptides. The peptides are composed from no. 1 to no. 7 of the figure that is selected from the group consisting of FIG. 11 to FIG. 18. And the novel milk-fermented product is used for suppressing the reduction of bone mineral density. Therefore, the novel milk-fermented product could be a component of foods, nutrient supplement or medicine for treating or preventing osteoporosis.
    Type: Application
    Filed: July 9, 2014
    Publication date: December 25, 2014
    Inventors: Chuan-Mu CHEN, Hsiao-Ling CHEN
  • Publication number: 20140120173
    Abstract: The present invention discloses a novel milk-fermented product comprising a group of peptides. The peptides are composed from no. 1 to no. 7 of the figure that is selected from the group consisting of FIG. 11 to FIG. 18. And the novel milk-fermented product is used for suppressing the reduction of bone mineral density. Therefore, the novel milk-fermented product could be a component of foods, nutrient supplement or medicine for treating or preventing osteoporosis.
    Type: Application
    Filed: October 26, 2012
    Publication date: May 1, 2014
    Applicant: National Chung Hsing University
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Patent number: 8313750
    Abstract: The invention provides a new type of a capsid protein VP1 of human enterovirus 71, named as MEL701-VP1 and functional/structural variants thereof, which is used for protection against enterovirus. The transgenic animal producing the protein, the composition comprising the protein and the method for production thereof are also provided.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: November 20, 2012
    Assignee: National Chung Hsing University
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Patent number: 8168192
    Abstract: The invention provides a new type of a capsid protein VP1 of human enterovirus 71, named as MEL701-VP1 and functional/structural variants thereof, which is used for protection against enterovirus. The transgenic animal producing the protein, the composition comprising the protein and the method for production thereof are also provided.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: May 1, 2012
    Assignee: National Chung Hsing University
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Publication number: 20110179508
    Abstract: The invention provides a new type of a capsid protein VP1 of human enterovirus 71, named as MEL701-VP1 and functional/structural variants thereof, which is used for protection against enterovirus. The transgenic animal producing the protein, the composition comprising the protein and the method for production thereof are also provided.
    Type: Application
    Filed: February 24, 2011
    Publication date: July 21, 2011
    Applicant: NATIONAL CHUNG HSING UNIVERSITY
    Inventors: CHUAN-MU CHEN, HSIAO-LING CHEN
  • Patent number: 7795234
    Abstract: The invention provides a transgenic animal producing low-lactose milk, which is transformed with a gene encoding an extracellular lactase-hydrolyzing enzyme cloned from a human small intestinal cDNA library. The invention also provides a new extracellular lactase-phlorizin hydrolase (ecLPH) gene that can express human lactase-hydrolyzing enzyme in the mammary gland of animals. The invention can be used in the production of low-lactose milk.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: September 14, 2010
    Assignee: National Chung Hsing University
    Inventors: Chuan-Mu Chen, Winston T. K. Cheng, Hsiao-Ling Chen
  • Publication number: 20100208399
    Abstract: An electrostatic discharge protection circuit includes: an electrostatic protection device coupled between a first reference voltage terminal and a signal pad for protecting a circuit coupled to the signal pad; a bipolar junction transistor including an emitter terminal coupled to the signal pad, a collector terminal coupled to a second reference voltage terminal, and a base terminal coupled to the first reference voltage terminal, wherein the bipolar junction transistor is a parasitic bipolar junction transistor of the electrostatic protection device; and a clamping circuit coupled to the bipolar junction transistor for clamping a conductivity of the bipolar junction transistor according to a signal received at the signal pad.
    Type: Application
    Filed: April 9, 2009
    Publication date: August 19, 2010
    Inventors: Jing-Chi Yu, Hsiao-Ling Chen, Yu-Lun Lu, Chang-Chih Hsieh
  • Patent number: 7763281
    Abstract: The present invention provides a novel antihypertensive peptide. Also provided are pharmaceutical and food compositions containing the antihypertensive peptide for treating hypertension or cardiovascular disease.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: July 27, 2010
    Assignees: Da-Yeh University, National Chung Hsing University
    Inventors: Hsiao-Ling Chen, Chuan-Mu Chen
  • Publication number: 20100125918
    Abstract: The invention provides a new type of a capsid protein VP1 of human enterovirus 71, named as MEL701-VP1 and functional/structural variants thereof, which is used for protection against enterovirus. The transgenic animal producing the protein, the composition comprising the protein and the method for production thereof are also provided.
    Type: Application
    Filed: November 19, 2008
    Publication date: May 20, 2010
    Applicant: National Chung Hsing University
    Inventors: Chuan-Mu Chen, Hsiao-Ling Chen
  • Publication number: 20090075896
    Abstract: The present invention provides a novel antihypertensive peptide. Also provided are pharmaceutical and food compositions containing the antihypertensive peptide for treating hypertension or cardiovascular disease.
    Type: Application
    Filed: September 17, 2007
    Publication date: March 19, 2009
    Inventors: Hsiao-Ling Chen, Chuan-Mu Chen
  • Patent number: 7501554
    Abstract: The invention provides a transgenic animal producing low-lactose milk, which is transformed with a gene encoding an extracellular lactase-hydrolyzing enzyme cloned from a human small intestinal cDNA library. The invention also provides a new extracellular lactase-phlorizin hydrolase (ecLPH) gene that can express human lactase-hydrolyzing enzyme in the mammary gland of animals. The invention can be used in the production of low-lactose milk.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: March 10, 2009
    Assignee: National Chung Hsing University
    Inventors: Chuan-Mu Chen, Winston T. K. Cheng, Hsiao-Ling Chen
  • Publication number: 20080090279
    Abstract: The invention provides a transgenic animal producing low-lactose milk, which is transformed with a gene encoding an extracellular lactase-hydrolyzing enzyme cloned from a human small intestinal cDNA library. The invention also provides a new extracellular lactase-phlorizin hydrolase (ecLPH) gene that can express human lactase-hydrolyzing enzyme in the mammary gland of animals. The invention can be used in the production of low-lactose milk.
    Type: Application
    Filed: September 20, 2007
    Publication date: April 17, 2008
    Applicant: National Chung Hsing University (a university of Taiwan)
    Inventors: Chuan-Mu Chen, Winston Cheng, Hsiao-Ling Chen
  • Publication number: 20070266451
    Abstract: The invention provides a transgenic animal producing low-lactose milk, which is transformed with a gene encoding an extracellular lactase-hydrolyzing enzyme cloned from a human small intestinal cDNA library. The invention also provides a new extracellular lactase-phlorizin hydrolase (ecLPH) gene that can express human lactase-hydrolyzing enzyme in the mammary gland of animals. The invention can be used in the production of low-lactose milk.
    Type: Application
    Filed: May 15, 2006
    Publication date: November 15, 2007
    Inventors: Chuan-Mu Chen, Winston Cheng, Hsiao-Ling Chen