Patents by Inventor Hsien-Jue (Steve) Chu

Hsien-Jue (Steve) Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5770211
    Abstract: This invention provides a recombinant raccoon poxvirus that expresses the nucleocapsid and transmembrane proteins of Feline Infectious Peritonitis Virus. The recombinant viruses are useful as vaccines, either alone or in combination with carriers and adjuvants.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 23, 1998
    Assignee: American Home Products Corporation
    Inventors: Terri Wasmoen, Lloyd Chavez, Hsien-Jue Chu
  • Patent number: 5733555
    Abstract: The invention provides an improved BRSV vaccine composition, which advantageously provides immunity from infection after a single administration. The composition comprises a modified live BRS virus and an adjuvant, which in combination provide immunity from BRSV infection after a single administration, and elicit an immune response specific to BRSV and including cell-mediated immunity and local (secretory IgA) immunity. In a preferred embodiment, the BRS virus is strain 375, and the adjuvant comprises an unsaturated turpin hydrocarbon, preferably squalene or squalane, and a polyoxypropylene-polyoxyethylene block copolymer, most preferably one where the copolymer has a polyoxypropylene (POP) component with an average molecular weight of about 3250 to 4000 and the polyoxyethylene (POE) component comprises about 10-20% of the total molecule. The adjuvant may optionally include a surfactant, preferably a polyoxyethylenesorbitan monooleate.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: March 31, 1998
    Assignee: American Home Products Corporation
    Inventor: Hsien-Jue Chu
  • Patent number: 5656275
    Abstract: This invention provides a recombinant raccoon poxvirus that expresses the nucleocapsid and transmembrane proteins of Feline Infectious Peritionitis Virus. The recombinant viruses are useful as vaccines, either alone or in combination with carriers and adjuvants.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 12, 1997
    Assignee: American Home Products Corporation
    Inventors: Terri Wasmoen, Lloyd Chavez, Hsien-Jue Chu
  • Patent number: 5242686
    Abstract: This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived therefrom, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent chlamydia, e.g. C. psittaci, infections or diseases in felines, and may also be combined with other vaccine compositions or therapy. A process for producing C. psittaci suitable for use in the production of safe and effective chlamydia vaccines, and a method for preventing chlamydia infections or diseases in felines, are also provided.
    Type: Grant
    Filed: November 7, 1990
    Date of Patent: September 7, 1993
    Assignee: American Home Products Corporation
    Inventors: Hsien-Jue Chu, Lloyd Chavez, William M. Acree, Lucille W. S. Chang