Abstract: A thermal control module for a bioseparation system, comprising: a thermal platform thermally coupled to the thermoelectric module, wherein the thermal platform comprises: a base, and at least a thermal block thermal conductively supported on the base, wherein the thermal block is structured to receive a receptacle containing at least a sample, and wherein the thermal block comprises a body comprising a split longitudinal block having two longitudinal sides defining a valley, wherein the facing walls of the sides each has a scalloped concave profile conforming to convex conical tube shaped profile of bottom surfaces of the wells of the receptacle tray; a heat sink; and a thermoelectric module thermal conductively coupled between the base of the thermal platform and the heat sink, heating/cooling the thermal platform in accordance with desired heating/cooling temperature profile.