Patents by Inventor Hsin-An Hou

Hsin-An Hou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139262
    Abstract: The present disclosure relates to a complex probiotic composition and a method for improving exercise performance of a subject with low intrinsic aerobic exercise capacity. The complex probiotic composition, which includes Lactobacillus rhamnosus GKLC1, Bifidobacterium lactis GKK24 and Clostridium butyricum GKB7, administered to the subject with the low intrinsic aerobic exercise capacity in a continuation period, can effectively reduce serum lactic acid and serum urea nitrogen after aerobic exercise, reduce proportion of offal fat and/or increase liver and muscle glycogen contents, thereby being as an effective ingredient for preparation of various compositions.
    Type: Application
    Filed: October 13, 2023
    Publication date: May 2, 2024
    Inventors: Chin-Chu CHEN, Yen-Lien CHEN, Shih-Wei LIN, Yen-Po CHEN, Ci-Sian WANG, Yu-Hsin HOU, Yang-Tzu SHIH, Ching-Wen LIN, Ya-Jyun CHEN, Jia-Lin JIANG, You-Shan TSAI, Zi-He WU
  • Patent number: 11967546
    Abstract: A semiconductor structure includes a first interposer; a second interposer laterally adjacent to the first interposer, where the second interposer is spaced apart from the first interposer; and a first die attached to a first side of the first interposer and attached to a first side of the second interposer, where the first side of the first interposer and the first side of the second interposer face the first die.
    Type: Grant
    Filed: July 21, 2022
    Date of Patent: April 23, 2024
    Assignee: Taiwan Semiconductor Manufacturing Co., Ltd.
    Inventors: Shang-Yun Hou, Hsien-Pin Hu, Sao-Ling Chiu, Wen-Hsin Wei, Ping-Kang Huang, Chih-Ta Shen, Szu-Wei Lu, Ying-Ching Shih, Wen-Chih Chiou, Chi-Hsi Wu, Chen-Hua Yu
  • Publication number: 20240069654
    Abstract: A touchpad device includes a substrate and a touch panel. The substrate includes a main plate, a first limiting plate, and a first flexible member. The main plate has a long side and a short side. The first limiting plate has a first stopping portion, the first flexible member is integrally connected between the long side and the first limiting plate, and the first limiting plate is adjacent to the short side. The touch panel is disposed above the substrate. The touch panel has a bottom surface, a pivot side of the bottom surface is disposed on the main plate, the first limiting plate of the substrate is fixed on the bottom surface and adjacent to a first side of the bottom surface, and the first stopping portion of the first limiting plate protrudes from an edge portion of the first side.
    Type: Application
    Filed: August 9, 2023
    Publication date: February 29, 2024
    Inventors: Po-Chun Hou, Po-Hsin Li, Chi-Hung Cheng
  • Patent number: 11766465
    Abstract: The present disclosure relates to as external composition for wound healing containing a Lactobacillus fermentation product, which comprises a Lactobacillus fermentation product as an effective component. The Lactobacillus fermentation product is a bacteria-free concentrated filtrate from fermentation of Lactobacillus plantarum and the effective component is loaded onto a pharmaceutically acceptable absorbent carrier or carrying agent. The external composition for wound healing has anti-inflammatory and healing promoting effects on a skin wound after applied directly onto the skin wound.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: September 26, 2023
    Assignee: GRAPE KING BIO LTD
    Inventors: Hsing-Chun Kuo, Chin-Chu Chen, Yen-Lien Chen, Shih-Wei Lin, Yen-Po Chen, Ci-Sian Wang, Yu-Hsin Hou, Yang-Tzu Shih, Ching-Wen Lin, Ya-Jyun Chen, Jia-Lin Jiang, You-Shan Tsai, Zi-He Wu
  • Patent number: 11752177
    Abstract: The present invention is related to a method of reducing tobacco addiction in a smoking subject with Lactobacillus fermentum GKF3, including daily administering an oral composition containing the Lactobacillus fermentum GKF3 to the smoking subject, in which the oral composition reduces the total amount of the nicotine metabolites in urine.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: September 12, 2023
    Assignee: GRAPE KING BIO LTD
    Inventors: Chin-Chu Chen, Yen-Lien Chen, Shih-Wei Lin, Yen-Po Chen, Ci-Sian Wang, Yu-Hsin Hou, Yang-Tzu Shih, Ching-Wen Lin, Ya-Jyun Chen, Jia-Lin Jiang, You-Shan Tsai, Zi-He Wu
  • Publication number: 20230128854
    Abstract: The present invention is related to a method of reducing tobacco addiction in a smoking subject with Lactobacillus fermentum GKF3, including daily administering an oral composition containing the Lactobacillus fermentum GKF3 to the smoking subject, in which the oral composition reduces the total amount of the nicotine metabolites in urine.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 27, 2023
    Inventors: Chin-Chu CHEN, Yen-Lien CHEN, Shih-Wei LIN, Yen-Po CHEN, Ci-Sian WANG, Yu-Hsin HOU, Yang-Tzu SHIH, Ching-Wen LIN, Ya-Jyun CHEN, Jia-Lin JIANG, You-Shan TSAI, Zi-He WU
  • Patent number: 11590180
    Abstract: The present invention provides a Bifidobacterium lactis GKK2, a composition comprising thereof and its use for improving asthma, especially for lowering airway resistance, reducing levels of non-specific and specific IgE in serum, alleviating bronchoconstriction and increasing levels of GSH reductase in liver tissue interstitial fluid to improve allergic asthma.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: February 28, 2023
    Assignee: GRAPE KING BIO LTD.
    Inventors: Chin-Chu Chen, Yen-Lien Chen, Shin-Wei Lin, Yen-Po Chen, Ci-Sian Wang, Yu-Hsin Hou, Yang-Tzu Shih, Ching-Wen Lin, Ya-Jyun Chen, Jia-Lin Jiang
  • Publication number: 20220152129
    Abstract: The present disclosure relates to as external composition for wound healing containing a Lactobacillus fermentation product, which comprises a Lactobacillus fermentation product as an effective component. The Lactobacillus fermentation product is a bacteria-free concentrated filtrate from fermentation of Lactobacillus plantarum and the effective component is loaded onto a pharmaceutically acceptable absorbent carrier or carrying agent. The external composition for wound healing has anti-inflammatory and healing promoting effects on a skin wound after applied directly onto the skin wound.
    Type: Application
    Filed: October 29, 2021
    Publication date: May 19, 2022
    Inventors: Hsing-Chun KUO, Chin-Chu CHEN, Yen-Lien CHEN, Shih-Wei LIN, Yen-Po CHEN, Ci-Sian WANG, Yu-Hsin HOU, Yang-Tzu SHIH, Ching-Wen LIN, Ya-Jyun CHEN, Jia-Lin JIANG, You-Shan TSAI, Zi-He WU
  • Publication number: 20220143114
    Abstract: The present invention provides an active substance of Lactic Acid Bacteria, a composition comprising thereof and its use for promoting longevity, especially for increasing Cisd2 gene expression, reducing mitochondrial damage and delaying aging conditions such as nerve degeneration and sarcopenia.
    Type: Application
    Filed: January 25, 2022
    Publication date: May 12, 2022
    Applicant: GRAPE KING BIO LTD.
    Inventors: Chin-Chu CHEN, Yen-Lien CHEN, Shin-Wei LIN, Yen-Po CHEN, Ci-Sian WANG, Yu-Hsin HOU, Yang-Tzu SHIH, Ching-Wen LIN, Ya-Jyun CHEN, Jia-Lin JIANG
  • Patent number: 11253556
    Abstract: The present invention provides a Lactobacillus fermentum GKF3, a composition comprising the strain and their use, in which the aforementioned Lactobacillus fermentum GKF3, deposited with accession numbers of BCRC 910824 and CGMCC 15203, can increase the levels of dopamine or/and serotonin in brain tissues, thereby improving the symptoms of the psychataxia such as decreased focus.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: February 22, 2022
    Assignee: GRAPE KING BIO LTD
    Inventors: Chin-Chu Chen, Yen-Lien Chen, Shih-Wei Lin, Szu-Yin Wu, Yen-Po Chen, Yu-Hsin Hou, Ci-Sian Wang, Yang-Tzu Shih, Jia-Lin Jiang
  • Publication number: 20210393585
    Abstract: The present disclosure provides a method for preventing and/or treating a stress-induced disease in a subject in need of such treatment, comprising administering to said subject an effective amount of tanshinone IIA or a derivative of tanshinone IIA, or a pharmaceutically acceptable salt, solvate, hydrate, isotopologue, or prodrug of tanshinone IIA or a derivative of tanshinone IIA, and optionally a pharmaceutically acceptable carrier or excipient.
    Type: Application
    Filed: June 19, 2020
    Publication date: December 23, 2021
    Inventors: Hsin-Hou CHANG, Der-Shan SUN
  • Patent number: 11197901
    Abstract: The present invention provides an active substance of Lactic Acid Bacteria, a composition comprising thereof and its use for promoting longevity, especially for increasing Cisd2 gene expression, reducing mitochondrial damage and delaying aging conditions such as nerve degeneration and sarcopenia.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: December 14, 2021
    Assignee: GRAPE KING BIO LTD.
    Inventors: Chin-Chu Chen, Yen-Lien Chen, Shin-Wei Lin, Yen-Po Chen, Ci-Sian Wang, Yu-Hsin Hou, Yang-Tzu Shih, Ching-Wen Lin, Ya-Jyun Chen, Jia-Lin Jiang
  • Publication number: 20210317414
    Abstract: The present disclosure provides a soluble P-selectin (sP-sel) interfering the interaction between stem cells and niches to mobilize stem cells from bone marrow. The mobilization of stem cells with sP-sel can treat a subject in need of preservation, repair, or regeneration of a tissue, or revascularization.
    Type: Application
    Filed: April 14, 2020
    Publication date: October 14, 2021
    Applicant: TZU CHI UNIVERSITY
    Inventors: Hsin-Hou CHANG, Der-Shan SUN
  • Patent number: 11058733
    Abstract: The present invention provides a Bifidobacterium lactis having active substances, a composition comprising the same, and a method of promoting longevity using the same by subjecting the composition to a subject, thereby increasing Cisd2 gene expression, reducing damage of mitochondria, delaying aging-related symptoms including nerve degeneration and sarcopenia, and so on.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: July 13, 2021
    Assignee: GRAPE KING BIO LTD
    Inventors: Chin-Chu Chen, Yen-Lien Chen, Shih-Wei Lin, Yen-Po Chen, Ci-Sian Wang, Yu-Hsin Hou, Yang-Tzu Shih, Ching-Wen Lin, Ya-Jyun Chen, Jia-Lin Jiang
  • Patent number: 11006358
    Abstract: A data transmission coordination system and a method thereof are provided. In the method, multiple terminal devices are grouped into a first sub-group and a second sub-group. The first and the second sub-groups respectively include at least one of the terminal devices and have different data transmission modes for uploading data. The power consumption of the data transmission mode of the first sub-group is higher than that of the second sub-group. In response to the first terminal device of the sub-group conforming to a replacement condition, a second terminal device of the second sub-group replaces the first terminal device, so that the first sub-group includes the second terminal device. The replaced first terminal device is associated to the second sub-group or not able to transmit depending on an operation situation. Accordingly, a whole lifetime of the system is increased.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: May 11, 2021
    Assignee: Sercomm Corporation
    Inventors: Fan-Yi Kuan, Hsin-An Hou
  • Publication number: 20200155623
    Abstract: The present invention provides a Lactobacillus fermentum GKF3, a composition comprising the strain and their use, in which the aforementioned Lactobacillus fermentum GKF3, deposited with accession numbers of BCRC 910824 and CGMCC 15203, can increase the levels of dopamine or/and serotonin in brain tissues, thereby improving the symptoms of the psychataxia such as decreased focus.
    Type: Application
    Filed: November 6, 2019
    Publication date: May 21, 2020
    Inventors: Chin-Chu CHEN, Yen-Lien CHEN, Shih-Wei LIN, Szu-Yin WU, Yen-Po CHEN, Yu-Hsin HOU, Ci-Sian WANG, Yang-Tzu SHIH, Jia-Lin JIANG
  • Patent number: 10584154
    Abstract: The invention creates engineered surface protein expression on vesicles for specific targeting and delivery of agents to autophagic and apoptotic cells. Moreover, the vesicles of the invention can achieve a synergistic effect on the targeting and drug delivery to autophagic and apoptotic cells and autophagic and apoptotic cells-containing tissues.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: March 10, 2020
    Assignee: TZU CHI UNIVERSITY
    Inventors: Hsin-Hou Chang, Der-Shan Sun
  • Publication number: 20200054696
    Abstract: The present invention provides an active substance of Lactic Acid Bacteria, a composition comprising thereof and its use for promoting longevity, especially for increasing Cisd2 gene expression, reducing mitochondrial damage and delaying aging conditions such as nerve degeneration and sarcopenia.
    Type: Application
    Filed: August 15, 2019
    Publication date: February 20, 2020
    Applicant: GRAPE KING BIO LTD.
    Inventors: Chin-Chu CHEN, Yen-Lien CHEN, Shin-Wei LIN, Yen-Po CHEN, Ci-Sian WANG, Yu-Hsin HOU, Yang-Tzu SHIH, Ching-Wen LIN, Ya-Jyun CHEN, Jia-Lin JIANG
  • Publication number: 20200054695
    Abstract: The present invention provides an active substance of Lactic Acid Bacteria, a composition comprising thereof and its use for promoting longevity, especially for increasing Cisd2 gene expression, reducing mitochondrial damage and delaying aging conditions such as nerve degeneration and sarcopenia.
    Type: Application
    Filed: August 15, 2019
    Publication date: February 20, 2020
    Applicant: GRAPE KING BIO LTD.
    Inventors: Chin-Chu CHEN, Yen-Lien CHEN, Shin-Wei LIN, Yen-Po CHEN, Ci-Sian WANG, Yu-Hsin HOU, Yang-Tzu SHIH, Ching-Wen LIN, Ya-Jyun CHEN, Jia-Lin JIANG
  • Publication number: 20200054691
    Abstract: The present invention provides a Bifidobacterium lactis GKK2, a composition comprising thereof and its use for improving asthma, especially for lowering airway resistance, reducing levels of non-specific and specific IgE in serum, alleviating bronchoconstriction and increasing levels of GSH reductase in liver tissue interstitial fluid to improve allergic asthma.
    Type: Application
    Filed: August 15, 2019
    Publication date: February 20, 2020
    Applicant: GRAPE KING BIO LTD.
    Inventors: Chin-Chu CHEN, Yen-Lien CHEN, Shin-Wei LIN, Yen-Po CHEN, Ci-Sian WANG, Yu-Hsin HOU, Yang-Tzu SHIH, Ching-Wen LIN, Ya-Jyun CHEN, Jia-Lin JIANG