Patents by Inventor Hsin-Hou Chang

Hsin-Hou Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PREVENTING AND/OR TREATING A STRESS-INDUCED DISEASE
    Publication number: 20210393585
    Abstract: The present disclosure provides a method for preventing and/or treating a stress-induced disease in a subject in need of such treatment, comprising administering to said subject an effective amount of tanshinone IIA or a derivative of tanshinone IIA, or a pharmaceutically acceptable salt, solvate, hydrate, isotopologue, or prodrug of tanshinone IIA or a derivative of tanshinone IIA, and optionally a pharmaceutically acceptable carrier or excipient.
    Type: Application
    Filed: June 19, 2020
    Publication date: December 23, 2021
    Inventors: Hsin-Hou CHANG, Der-Shan SUN
  • METHODS FOR MOBILIZING STEM CELLS
    Publication number: 20210317414
    Abstract: The present disclosure provides a soluble P-selectin (sP-sel) interfering the interaction between stem cells and niches to mobilize stem cells from bone marrow. The mobilization of stem cells with sP-sel can treat a subject in need of preservation, repair, or regeneration of a tissue, or revascularization.
    Type: Application
    Filed: April 14, 2020
    Publication date: October 14, 2021
    Applicant: TZU CHI UNIVERSITY
    Inventors: Hsin-Hou CHANG, Der-Shan SUN
  • Vesicles comprising lectins expressed on the surface and methods of use thereof to deliver an agent to autophagic and apoptotic cells
    Patent number: 10584154
    Abstract: The invention creates engineered surface protein expression on vesicles for specific targeting and delivery of agents to autophagic and apoptotic cells. Moreover, the vesicles of the invention can achieve a synergistic effect on the targeting and drug delivery to autophagic and apoptotic cells and autophagic and apoptotic cells-containing tissues.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: March 10, 2020
    Assignee: TZU CHI UNIVERSITY
    Inventors: Hsin-Hou Chang, Der-Shan Sun
  • DELIVERY OF AN AGENT TO AUTOPHAGIC AND APOPTOTIC CELLS BY VESICLES WITH A PROTEIN EXPRESSED ON SURFACE THEREOF
    Publication number: 20190194281
    Abstract: The invention creates engineered surface protein expression on vesicles for specific targeting and delivery of agents to autophagic and apoptotic cells. Moreover, the vesicles of the invention can achieve a synergistic effect on the targeting and drug delivery to autophagic and apoptotic cells and autophagic and apoptotic cells-containing tissues.
    Type: Application
    Filed: December 27, 2017
    Publication date: June 27, 2019
    Inventors: Hsin-Hou CHANG, Der-Shan SUN
  • METHODS OF REDUCING HYPOXIC STRESS IN A MAMMAL BY ADMINISTERING SOLUBLE P-SELECTIN
    Publication number: 20130045924
    Abstract: The present invention provides a use of soluble P-selectin in treating systemic hemorrhagic conditions, stabilizing blood pressure, and protecting hypoxic/ischemic tissues. Also provided is a use of anthrax lethal toxin in treating thrombotic conditions.
    Type: Application
    Filed: December 29, 2006
    Publication date: February 21, 2013
    Inventors: Hsin-Hou Chang, Der-Shan Sun
  • Methods of reducing hypoxic stress in a mammal by administering soluble P-selectin
    Patent number: 8377887
    Abstract: The present invention provides a use of soluble P-selectin in treating systemic hemorrhagic conditions, stabilizing blood pressure, and protecting hypoxic/ischemic tissues. Also provided is a use of anthrax lethal toxin in treating thrombotic conditions.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: February 19, 2013
    Inventors: Hsin-Hou Chang, Der-Shan Sun
  • Use of soluble P-selectin and anthrax lethal toxin
    Publication number: 20050059582
    Abstract: The present invention provides a use of soluble P-selectin in treating systemic hemorrhagic conditions, stabilizing blood pressure, and protecting hypoxic/ischemic tissues. Also provided is a use of anthrax lethal toxin in treating thrombotic conditions.
    Type: Application
    Filed: July 29, 2004
    Publication date: March 17, 2005
    Inventors: Hsin-Hou Chang, Der-Shan Sun