Abstract: A grooved incisor blade set for paper shredders is disclosed. A blade includes a crown, a groove juxtaposed with the crown, and a center hole for a cutting arbor, where the crown and the groove define a relief channel. A stair-shaped, U-shaped or V-shaped blade assembly is described. In one embodiment, a notched grooved incisor blade having notches proximate to the central hole comes in contact with a mating grooved incisor blade also having a central hole. Force is applied to the mating blade to displace some of the body of the mating blade into the notches, affixing the blades together. A method for forming shredder cutting blades includes providing a strip of metal, forming a crown in the strip of metal, forming a relief groove juxtaposed to the crown in the strip of metal, thereby forming a relief channel, and trimming the grooved incisor blade of excess metal.

Abstract: The present invention provides a method for evaluating physiological state of motor neurons in a subject.

Abstract: A safety inlet apparatus for a paper feed opening of a shredder, with cutting cylinders including an upper casing having a feed end with a safety dam with upper and lower indices. An angled plate means set apart from the upper casing forms the paper feed opening. A safety plate with a distal index end is provided, which is formed to traverse the feed opening from the angled plate to the safety dam. Also included is a pivot, and a power control switch. The pivot is configured to facilitate traversal of the safety plate distal index from the angled plate to the safety dam. The power limit switch is on the upper casing, apart from the pivot member. The traversal of the safety plate distal index end to the safety dam lower index causes the power control switch to stop comminution. A buckle bit plate provides open and closed detents.

Abstract: The invention is directed to a touch-sensitive paper shredder control system. The touching feature is implemented through a series of electronic circuits, taking input from a conductive touch panel on the shredder feed throat, processing the signal, and through a motor driving circuit, stopping the mechanical parts of the shredder. The system has a touch detection circuit unit, which contains a bioelectricity controlled switching circuit to sense the conductive touch panel. The bioelectricity controlled switching circuit is configured to trigger a ground switching circuit in the touch detection circuit unit which outputs to a multifunction control circuit unit. The control circuit unit then takes care of the remaining protection issues. The touching device for paper shredders protects humans and other living beings including pets from injuries through automatic and real time monitoring. The complete control process is both safe and sensitive.

Abstract: The invention is directed to a permittivity-based paper shredder control system. The touching feature is implemented through a series of electronic circuits, taking input from a conductive touch panel on the shredder feed throat, processing the signal, and through a motor driving circuit, stopping the mechanical parts of the shredder. The system has a touch detection circuit unit, which contains a bioelectricity controlled switching circuit to sense the conductive touch panel. The bioelectricity controlled switching circuit is configured to trigger a ground switching circuit in the touch detection circuit unit which outputs to a multifunction bioshield controller. The bioshield controller then takes care of the remaining protection issues. The touching device for paper shredders protects humans and other living beings including pets from injuries through automatic and real time monitoring. The complete control process is both safe and sensitive.

Abstract: The present invention directs to a transgenic NRIP knockout mouse, the genome of which is manipulated to comprise a disruption of a nuclear receptor interaction protein (NRIP) gene, wherein the NRIP gene is disrupted by deletion of exon 2, the mouse exhibits a phenotype comprising abnormal muscular function. The present invention also directs to a method for making a transgenic NRIP knockout mouse whose genome comprises a homozygous disruption of the NRIP gene, the mouse exhibits abnormal muscular function.

Abstract: The present invention provides a kit for diagnosing the cardiomyopathy comprising an antibody or oligonucleotide for measuring an expression level of nuclear receptor interaction protein (NRIP). The present invention also provides a method of predicting a risk of cardiomyopathy for a subject. The present invention further provides a method of screening an agent for treating cardiomyopathy.

Abstract: Composition, apparatus, and methods of composition and apparatus manufacture, for sharpening a paper shredder blade. Composition includes grinding powder, thickening agent, and additive. The thickening agent may be a white oil, an animal oil, an vegetable oil, or a stearine wax. The additive may be an antirust powder, an antiwear powder, an antistatic powder, or an antioxidation powder. The grinding composition is dispensed into a polyethylene film, and sealed to form the grinding apparatus, as a grinding sheet or a grinding packet. A method for forming a grinding sheet includes selecting the constituent materials for a grinding composition; stirring the constituent grinding composition materials; heating the constituent materials to melting; mixing the constituent materials, while melting and intermixing; cooling and packaging the grinding composition to form a grinding sheet or packet.

Abstract: A safety inlet apparatus for a paper feed opening of a shredder, with cutting cylinders including an upper casing having a feed end with a safety dam with upper and lower indices. An angled plate means set apart from the upper casing forms the paper feed opening. A safety plate with a distal index end is provided, which is formed to traverse the feed opening from the angled plate to the safety dam. Also included is a pivot, and a power control switch. The pivot is configured to facilitate traversal of the safety plate distal index from the angled plate to the safety dam. The power limit switch is on the upper casing, apart from the pivot member. The traversal of the safety plate distal index end to the safety dam lower index causes the power control switch to stop comminution. A buckle bit plate provides open and closed detents.

Abstract: Composition, apparatus, and methods of composition and apparatus manufacture, for sharpening a paper shredder blade. Composition includes grinding powder, thickening agent, and additive. The thickening agent may be a white oil, an animal oil, a vegetable oil, or a stearine wax. The additive may be an antirust powder, an antiwear powder, an antistatic powder, or an antioxidation powder. The grinding composition is dispensed into a polyethylene film, and sealed to form the grinding apparatus, as a grinding sheet or a grinding packet. A method for forming a grinding sheet includes selecting the constituent materials for a grinding composition; stirring the constituent grinding composition materials; heating the constituent materials to melting; mixing the constituent materials, while melting and intermixing; cooling and packaging the grinding composition to form a grinding sheet or packet.

Abstract: Composition, apparatus, and methods of composition and apparatus manufacture, for sharpening a paper shredder blade. Composition includes grinding powder, thickening agent, and additive. The thickening agent may be a white oil, an animal oil, an vegetable oil, or a stearine wax. The additive may be an antirust powder, an antiwear powder, an antistatic powder, or an antioxidation powder. The grinding composition is dispensed into a polyethylene film, and sealed to form the grinding apparatus, as a grinding sheet or a grinding packet. A method for forming a grinding sheet includes selecting the constituent materials for a grinding composition; stirring the constituent grinding composition materials; heating the constituent materials to melting; mixing the constituent materials, while melting and intermixing; cooling and packaging the grinding composition to form a grinding sheet or packet.

Abstract: Composition, apparatus, and methods of composition and apparatus manufacture, for sharpening a paper shredder blade. Composition includes grinding powder, thickening agent, and additive. The thickening agent may be a white oil, an animal oil, an vegetable oil, or a stearine wax. The additive may be an antirust powder, an antiwear powder, an antistatic powder, or an antioxidation powder. The grinding composition is dispensed into a polyethylene film, and sealed to form the grinding apparatus, as a grinding sheet or a grinding packet. A method for forming a grinding sheet includes selecting the constituent materials for a grinding composition; stirring the constituent grinding composition materials; heating the constituent materials to melting; mixing the constituent materials, while melting and intermixing; cooling and packaging the grinding composition to form a grinding sheet or packet.

Abstract: A grooved incisor blade set for paper shredders is disclosed. A blade includes a crown, a groove juxtaposed with the crown, and a center hole for a cutting arbor, where the crown and the groove define a relief channel. A stair-shaped, U-shaped or V-shaped blade assembly is described. In one embodiment, a notched grooved incisor blade having notches proximate to the central hole comes in contact with a mating grooved incisor blade also having a central hole. Force is applied to the mating blade to displace some of the body of the mating blade into the notches, affixing the blades together. A method for forming shredder cutting blades includes providing a strip of metal, forming a crown in the strip of metal, forming a relief groove juxtaposed to the crown in the strip of metal, thereby forming a relief channel, and trimming the grooved incisor blade of excess metal.

Abstract: Safety inlet apparatus for a shredder paper feed opening includes upper cover, safety cover, paper feed passage block, and elastic member. A safety cover end section covers the shredder paper feed opening, and rotatably couples to the upper cover. Paper feed passage block is positioned between shredder paper feed opening and elastic member, and the safety cover pivots to the upper cover. Paper feed passage block is slidably arranged on the upper cover near shredder paper feed opening, connecting to the safety cover second end section. Elastic member ends respectively connect to the upper cover inner wall and the paper feed passage block. Paper feed passage block may be fixed to, or integrated with, the second end section, or may limit a stud on the second end section.

Abstract: The present invention relates to a pins or staples removable structure of automatic shredders which comprises a shredder core, a paper press board assembly and a paper support board assembly fixed to the shredder core and arranged cooperatedly, and a clamping device, the paper support board assembly comprises a paper support board and a pick-up mechanism mounted to the paper support board, the clamping device is fixed to the paper press board assembly and the shredder core/the paper support board respectively, for clamping the paper to be shredded to the paper support board during the process of shredding paper, the paper support board has a paper inlet above the blade assembly of the shredder core, the distance between the outer end of the paper support board and the outer end of the pick-up mechanism for clamping the paper to be shredded is less than the length of the whole paper to be shredded, the pins or staples removable structure of automatic shredders further comprises a magnet positioned in the outer

Abstract: The present invention relates to an automatic shredder without choosing the number of paper to be shredded which comprises a shredder core and an automatic paper feeding device, the automatic paper feeding device comprises a driving mechanism, a paper support box, a pick-up mechanism and a paper press box, the driving mechanism is fixed on the shredder core and connected with the pick-up mechanism for driving the pick-up mechanism, the paper support box comprises a first zone and a second zone, the pick-up mechanism is positioned between the first zone and the second zone and fixed to the paper support box, and its paper feeding direction is towards the second zone, one end of the paper press box is pivoted with the paper support box, the other end of the paper press box is connected detachable with the paper support box, the paper support box is fixed on the shredder core, and the second zone has a paper inlet positioned above the blade assembly of the shredder core, a magnet is positioned in the first zone,

Abstract: The present invention directed to a method for modulating the expression level of slow myosin comprising administering to a subject in need thereof a therapeutically effective amount of nuclear receptor interaction protein (NRIP) modulator and calmodulin, and a pharmaceutically acceptable carrier.

Abstract: The present invention relates to a method for treating a subject suffering from growth of AR-containing tumor cells, comprising administrating the subject an effective amount of DDB2. The present invention also relates to a kit for the diagnosis of cancer.

Abstract: Thin shredder blade having blade points without steps, including blade body and cutting part located on periphery of blade body and includes a blade point. The cutting part includes a primary protrusion protruding from the cutting part. The primary protrusion includes a top, an inclined plane extending between the top and blade point, and an acute angle formed by inclined plane and blade body. The plane is an inverted triangle. The cutting part further includes first and second hemlines extending from the blade body and intersecting to the blade point. A first plane extends between the top and first hemline and intersects with the inclined plane. The blade body includes a large protrusion which protrudes in the same direction as the primary protrusion. The blade sets formed by the thin blades and the manufacturing method of the thin blades are provided.

Abstract: Thin shredder blade having blade points without steps, including blade body and cutting part located on periphery of blade body and includes a blade point. The cutting part includes a primary protrusion protruding from the cutting part. The primary protrusion includes a top, an inclined plane extending between the top and blade point, and an acute angle formed by inclined plane and blade body. The plane is an inverted triangle. The cutting part further includes first and second hemlines extending from the blade body and intersecting to the blade point. A first plane extends between the top and first hemline and intersects with the inclined plane. The blade body includes a large protrusion which protrudes in the same direction as the primary protrusion. The blade sets formed by the thin blades and the manufacturing method of the thin blades are provided.