Abstract: A method for estimating an inhale dose when a drug is delivered to a person using an inhaler is disclosed. A predicted inhale dose (PID) of the drug is estimated based on at least one first-type parameter and at least one second-type parameter. The first-type parameter is related to a breath pattern of the person, and the second-type parameter is related to the inhaler.

Abstract: A method and a circuit system for driving a nebulizer are provided. When the nebulizer receives acoustic waves, a control circuit extracts audio signals from the acoustic waves. Afterwards, the control circuit determines if the audio signals are within a predetermined frequency range, and can determine whether or not to drive a circuit to produce an aerosol based on the audio signals. Further, a volume of the acoustic waves can also be used to determine whether or not to produce the aerosol, and also determine an output rate of the aerosol. The circuit system of the nebulizer includes an audio receiver for receiving the acoustic waves, an aerosol generator for producing the aerosol, and the control circuit used to control a driving circuit of the aerosol generator to drive a vibrational element to produce the aerosol through vibration in response to the audio signals and the volume.