Patents by Inventor Hsin-Jan Yao

Hsin-Jan Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230201291
    Abstract: A method for extracting flavone aglycones in Chrysanthemum morifolium is provided. The method includes: (a) immersing a Chrysanthemum morifolium raw material in water or an aqueous solution to perform an immersion procedure for 3.5 hours or more to obtain an immersion sample; and (b) adding an extraction solvent to the immersion sample to perform an extraction procedure 5-60 minutes to obtain an extract. The Chrysanthemum morifolium raw material includes at least one of the following parts of Chrysanthemum morifolium: whole plant, roots, stems, leaves and flowers.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 29, 2023
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hsin Jan YAO, Yu-Wen CHEN, Chu-Hsun LU, I-Hong PAN, Wen-Yin CHEN, Tsung-Lin YANG, Angela GOH
  • Patent number: 10987394
    Abstract: The present disclosure provides a method for preparing an extract of Chrysanthemum morifolium with an effect of treating skin diseases, including: (a) performing an extraction procedure on Chrysanthemum morifolium with an extraction solvent to obtain an extract solution; and (b) adding at least one glycoside hydrolases to the extract solution to make an enzyme reaction occur to produce a precipitate, wherein the precipitate is the extract of Chrysanthemum morifolium with an effect of treating skin diseases.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: April 27, 2021
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng Pan, Hsin-Jan Yao, Chu-Hsun Lu, Shu-Fang Wen, Po-Yao Hsu, Ming-Han Li, Kai-An Chuang, Chih-Hsuan Chang
  • Publication number: 20190192597
    Abstract: The present disclosure provides a method for preparing an extract of Chrysanthemum morifolium with an effect of treating skin diseases, including: (a) performing an extraction procedure on Chrysanthemum morifolium with an extraction solvent to obtain an extract solution; and (b) adding at least one glycoside hydrolases to the extract solution to make an enzyme reaction occur to produce a precipitate, wherein the precipitate is the extract of Chrysanthemum morifolium with an effect of treating skin diseases.
    Type: Application
    Filed: December 22, 2017
    Publication date: June 27, 2019
    Applicant: Industrial Technology Research Institute
    Inventors: I-Horng PAN, Hsin-Jan YAO, Chu-Hsun LU, Shu-Fang WEN, Po-Yao HSU, Ming-Han LI, Kai-An CHUANG, Chih-Hsuan CHANG
  • Patent number: 9682062
    Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: June 20, 2017
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng Pan, Hsin-Jan Yao, Mei-Wei Lin, I-Huang Lu, Hsin-Chieh Wu, Hsiang-Wen Tseng, Ching-Huai Ko, Chun-Chung Wang, Zong-Keng Kuo, Shyh-Horng Lin, Yi-Cheng Cheng, Tien-Soung Tong
  • Patent number: 9603882
    Abstract: The disclosure provides a method for modulating Th17 cells, including: administering an Antrodia cinnamomea (also named Antrodia camphorata or Taiwanofungus camphoratus) extract to a subject in need thereof, wherein the Antrodia cinnamomea extract has an effect of modulating Th17 cells. The Antrodia cinnamomea extract may include a fruiting body extract of Antrodia cinnamomea or a mycelium extract of Antrodia cinnamomea.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: March 28, 2017
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng Pan, Shu-Fang Wen, Ming-Han Li, Hsin-Jan Yao, Hsin-Chieh Wu, I-Huang Lu, Joung-Liang Lan, Der-Yuan Chen, Chi-Chien Lin, Ching Lu
  • Publication number: 20160008319
    Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.
    Type: Application
    Filed: September 24, 2015
    Publication date: January 14, 2016
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
  • Publication number: 20150050315
    Abstract: The disclosure provides a method for modulating Th17 cells, including: administering an Antrodia cinnamomea (also named Antrodia camphorata or Taiwanofungus camphoratus) extract to a subject in need thereof, wherein the Antrodia cinnamomea extract has an effect of modulating Th17 cells. The Antrodia cinnamomea extract may include a fruiting body extract of Antrodia cinnamomea or a mycelium extract of Antrodia cinnamomea.
    Type: Application
    Filed: July 3, 2014
    Publication date: February 19, 2015
    Inventors: I-Horng PAN, Shu-Fang WEN, Ming-Han LI, Hsin-Jan YAO, Hsin-Chieh WU, I-Huang LU, Joung-Liang LAN, Der-Yuan CHEN, Chi-Chien LIN, Ching LU
  • Publication number: 20140170250
    Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 19, 2014
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
  • Publication number: 20140161837
    Abstract: The disclosure provides a vaccine adjuvant, including a polysaccharide derived from Antrodia camphorata (also named Antrodia cinnamomea or Taiwanofungus camphoratus) fruiting body, wherein the molecular weight of the polysaccharide is greater than 100 K Da. Furthermore, the polysaccharide is obtained by an extraction process, and the extraction process includes: (a) adding powder of the Antrodia camphorata fruiting body into water to form a mixture; (b) heating the mixture under reflux; (c) after step (b), removing an insoluble matter from the mixture; (d) after step (c), adding ethanol into the mixture to perform a precipitating step and obtain a precipitate; and (e) performing an isolating step to the precipitate to obtain a fraction the molecular weight of which is greater than 100 K Da of the precipitate.
    Type: Application
    Filed: December 9, 2013
    Publication date: June 12, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: I-Horng PAN, I-Haung LU, Hsin-Jan YAO, Hsin-Chieh WU, Chi-Chien LIN
  • Publication number: 20090280200
    Abstract: An herbal extract which induces immune cells to produce interferon and activates Toll-like receptors and a preparation method thereof are provided. The herbal extract is extracted from an effective amount of raw material including Glycyrrhizae Radix, Bupleuri Radix, Scutellariae Radix, Schisandrae Fructus and Paeoniae Rubra Radix. Glycyrrhizae Radix, Bupleuri Radix, Scutellariae Radix, Schisandrae Fructus and Paeoniae Rubra Radix have a weight ratio of 1-5:1-5:1-5:1-3:1-3.
    Type: Application
    Filed: June 30, 2008
    Publication date: November 12, 2009
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I Horng PAN, Lain-Tze LEE, Chih-Lung CHEN, Hsin-Jan YAO, Chu-Hsun LU, Chen Hsuan LIN, Ya-Yan YANG, Hsin-Hsin SHEN, Ming-Feng CHEN
  • Patent number: 6635758
    Abstract: An aqueous two-phase system for extracting glycosides from a herb includes the extractive solution, about 5 wt %-30 wt % of salt, about 5 wt %-30 wt % of polyol and selectively about 0 wt %-30 wt % of alcohols. The salt can be dihydrogen phosphate, hydrogen phosphate and phosphate or a mixture thereof, and it also can be sulfates, chlorides, oxalates, or acetates. In addition, a process for extracting glycosides using an aqueous two-phase system is disclosed. The procedures includes preparation of extractive solution, concentration, phase separation, drying, washing with solvent, cooling, filtration and drying of the final products.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: October 21, 2003
    Assignee: Industrial Technology Research Institute
    Inventors: I-Hong Pan, Chu-Hsun Lu, Hsi-Ho Chiu, Lain-Tze Lee, Hsin-Jan Yao
  • Publication number: 20020038020
    Abstract: An aqueous two-phase system for extracting glycosides from a herb includes the extractive solution, about 5 wt %-30 wt % of salt, about 5 wt %-30 wt % of polyol and about 0.5 wt %-30 wt % of alcohols. The salt can be dihydrogen phosphate, hydrogen phosphate and phosphate or a mixture thereof, and it also can be sulfates, chlorides, oxalates, or acetates. In addition, a process for extracting glycosides using an aqueous two-phase system is disclosed. The procedures includes preparation of extractive solution, concentration and drying, phase separation, concentration of the water layer and drying, washing with solvent, sonication, centrifugation, concentration of filtrate and drying of the final products.
    Type: Application
    Filed: June 26, 2001
    Publication date: March 28, 2002
    Inventors: I-Horng Pan, Lain-Tze Lee, His-Ho Chiu, Huei-Ju Liu, Hsin-Jan Yao