Abstract: A light source module and a display device are provided. The light source module includes a light source, a light guide plate, and an optical film set including multiple first optical microstructures having a first surface, multiple second optical microstructures having a second surface, and multiple third optical microstructures having a third surface. Each of the multiple first optical microstructures has a first vertex angle, each of the multiple second optical microstructures has a second vertex angle, and each of the multiple third optical microstructures has a third vertex angle. The third vertex angle is less than the first vertex angle, and the first vertex angle is less than or equal to the second vertex angle. By configuring the aforementioned optical microstructures, the light source module of the disclosure may greatly improve the collimation of light and has favorable luminance.

Abstract: An artificial shuttlecock includes a ball head, a plurality of feathers, and a plurality of stems. Each of the feathers includes a notch. The notch is disposed on an outer edge of the feather. A ball head end of the stem is connected to the ball head, and a feather end is connected to the feather. The stem includes a body, which tapers from the end close to the ball end to the feather end. The end of the body close to the ball end has a first width, and the body has a second width at the feather. The first width is between 2.1 mm and 2.4 mm, and the second width is between 0.4 mm and 0.6 mm.

Abstract: An image sensor device has a first number of first pixels disposed in a substrate and a second number of second pixels disposed in the substrate. The first number is substantially equal to the second number. A light-blocking structure disposed over the first pixels and the second pixels. The light-blocking structure defines a plurality of first openings and second openings through which light can pass. The first openings are disposed over the first pixels. The second openings are disposed over the second pixels. The second openings are smaller than the first openings. A microcontroller is configured to turn on different ones of the second pixels at different points in time.

Abstract: A method for fabricating semiconductor device includes the steps of: providing a substrate having a first region and a second region; forming a first fin-shaped structure on the first region and a second fin-shaped structure on the second region; forming a patterned mask on the second region; and performing a process to enlarge the first fin-shaped structure so that the top surfaces of the first fin-shaped structure and the second fin-shaped structure are different.

Abstract: A package structure including a semiconductor die, a redistribution circuit structure and an electronic device is provided. The semiconductor die is laterally encapsulated by an insulating encapsulation. The redistribution circuit structure is disposed on the semiconductor die and the insulating encapsulation. The redistribution circuit structure includes a colored dielectric layer, inter-dielectric layers and redistribution conductive layers embedded in the inter-dielectric layers. The electronic device is disposed over the colored dielectric layer and electrically connected to the redistribution circuit structure.

Abstract: A method for manufacturing a semiconductor structure includes forming a plurality of dummy structures spaced apart from each other, forming a plurality of dielectric spacers laterally covering the dummy structures to form a plurality of trenches defined by the dielectric spacers, filling a conductive material into the trenches to form electrically conductive features, selectively depositing a capping material on the electrically conductive features to form a capping layer, removing the dummy structures to form a plurality of recesses defined by the dielectric spacers, filling a sacrificial material into the recesses so as to form sacrificial features, depositing a sustaining layer on the sacrificial features, and removing the sacrificial features to form air gaps confined by the sustaining layer and the dielectric spacers.

Abstract: The present disclosure relates to a vaccine composition, comprising a recombinant lipidated FLIPr (rLF), and the use thereof in enhancing humoral and cellular immune responses. The recombinant lipidated FLIPr of present invention may be used as a vaccine candidate that can induce anti-FLIPr responses to overcome FLIPr-mediated inhibition. And unexpectedly, the recombinant lipidated FLIPr may be used as an adjuvant that can enhance other vaccine immune responses, especially in subunit vaccines and inactivated virus vaccines.

Abstract: The present invention relates to a composition of subunit dengue vaccine comprising a fusion protein of conjugating or connecting delta C nonstructural protein 1 (NS1?C or truncated NS1?C) to at least one polypeptides of NS3c (or truncated NS3c) and/or consensus envelope protein domain III (cEDIII), thereby enhancing better protection against DENV challenge and alleviating associated pathological effects.

Abstract: A light source module includes a light guide plate, light emitting elements, a prism sheet and a reflective sheet. The light guide plate has a light incident surface, a light emitting surface and a bottom surface. The light incident surface is connected to the light emitting surface and the bottom surface. The light emitting elements are disposed beside the light incident surface. The prism sheet is disposed beside the light emitting surface and includes prism pillars. The reflective sheet is disposed beside the bottom surface and includes a substrate and pyramidal structures. The substrate has a reflective surface. The pyramidal structures are disposed on the reflective surface. Each pyramidal structure has optical side surfaces. Each optical side surface has a bottom edge connected to the reflective surface. One optical side surface faces the light incident surface, and the respective bottom edge is parallel to the light incident surface.

Abstract: A backlight module includes a light-emitting element, a quantum dot film, an optical film and a light adjusting element. The light-emitting element is adapted to emit a blue light. The quantum dot film is adapted to converting a first portion and a second portion of the blue light into a red light and a green light, respectively. The optical film is disposed on the quantum dot film. The light adjusting element is disposed between the optical film and the quantum dot film. The light adjusting element has a first surface and a second surface respectively facing the quantum dot film and the optical film. The first surface has multiple first optical microstructures. The first optical microstructures include multiple cones protruding toward the quantum dot film. Moreover, a display apparatus including the backlight module is also provided.

Abstract: Provided is a pharmaceutical composition, including an antigen fusion protein which includes an antigen and an antagonist of an Fc gamma receptor. Also provided is a method of enhancing immunogenicity of an antigen, including conjugating the antigen with an antagonist of an Fc gamma receptor to form an antigen fusion protein. Also provided is a method of enhancing an immune response to an antigen in a subject, including administering to the subject an effective amount of an antigen fusion protein which includes an antigen and an antagonist of an Fc gamma receptor. The present invention may be applied in the development of potent vaccines based on targeting vaccine antigens to antigen-presenting cells via binding to Fc gamma receptors.

Abstract: Described herein are an immunogenic peptide containing the sequence of CLDSLGQWN (SEQ ID NO:2) and a method of using the peptide for treating cancer.

Abstract: The present invention relates to a composition of subunit dengue vaccine comprising a fusion protein of conjugating or connecting delta C nonstructural protein 1 (NS1?C or truncated NS1?C) to at least one polypeptides of NS3c (or truncated NS3c) and/or consensus envelope protein domain III (cEDIII), thereby enhancing better protection against DENV challenge and alleviating associated pathological effects.

Abstract: The present invention discloses a DAC device including a positive DAC, a negative DAC and an output circuit. The positive DAC is configured to perform a digital-to-analog converting operation on a digital input signal based on a first pulse signal to generate a first analog signal, wherein the first analog signal comprises a convolution result of the first pulse signal and the digital input signal. The negative DAC is configured to perform the digital-to-analog converting operation on the digital input signal based on a second pulse signal to generate a second analog signal, wherein the second analog signal comprises a convolution result of the second pulse signal and the digital input signal. The output circuit is configured to generate an output analog signal according to the first analog signal and the second analog signal.

Abstract: A SAR ADC includes a first capacitor array, a first comparator, a second capacitor array, a second comparator, an arbiter and a control circuit. The first capacitor array is arranged for receiving an input signal to generate a first signal. The first comparator is arranged for comparing the first signal with a first reference signal to generate a first comparison result. The second capacitor array is arranged for receiving the input signal to generate a second signal. The second comparator is arranged for comparing the second signal with a second reference signal to generate a second comparison result. The arbiter is arranged for generating an arbitration result according to the first comparison result and the second comparison result. The control circuit is arranged for generating an output signal according to the first comparison result, the second comparison result and the arbitration result.

Abstract: Provided is a pharmaceutical composition, including an antigen fusion protein which includes an antigen and an antagonist of an Fc gamma receptor. Also provided is a method of enhancing immunogenicity of an antigen, including conjugating the antigen with an antagonist of an Fc gamma receptor to form an antigen fusion protein. Also provided is a method of enhancing an immune response to an antigen in a subject, including administering to the subject an effective amount of an antigen fusion protein which includes an antigen and an antagonist of an Fc gamma receptor. The present invention may be applied in the development of potent vaccines based on targeting vaccine antigens to antigen-presenting cells via binding to Fc gamma receptors.

Abstract: Described herein are an immunogenic peptide containing the sequence of CLDSLGQWN (SEQ ID NO:2) and a method of using the peptide for treating cancer.

Abstract: A SAR ADC includes a first capacitor array, a first comparator, a second capacitor array, a second comparator, an arbiter and a control circuit. The first capacitor array is arranged for receiving an input signal to generate a first signal. The first comparator is arranged for comparing the first signal with a first reference signal to generate a first comparison result. The second capacitor array is arranged for receiving the input signal to generate a second signal. The second comparator is arranged for comparing the second signal with a second reference signal to generate a second comparison result. The arbiter is arranged for generating an arbitration result according to the first comparison result and the second comparison result. The control circuit is arranged for generating an output signal according to the first comparison result, the second comparison result and the arbitration result.

Abstract: A composition in a water-in-oil-in-water (W/O/W) emulsion is disclosed. The composition comprises: (a) a continuous aqueous phase, comprising H2O; (b) an oil phase or an oil shell, dispersed in the continuous aqueous phase; and (c) a hydrophilic polymer, stabilizing an interface between the continuous aqueous phase and the oil phase or the oil shell to form the water-in-oil-in-water (W/O/W) emulsion. The oil phase or the oil shell comprises: (i) oil; (ii) an internal aqueous phase, dispersed within the oil or the oil shell; and (iii) a lipophilic sorbitan-polyester conjugate, stabilizing an interface between the oil and the inner aqueous phase to form a water-in-oil (W/O) emulsion. The lipophilic sorbitan-polyester conjugate comprises: (1) sorbitan; and (2) poly(lactide-co-?-caprolactone) or polylactic acid (polylactide), conjugated to the sorbitan.

Abstract: A composition in a water-in-oil-in-water (W/O/W) emulsion is disclosed. The composition comprises: (a) a continuous aqueous phase, comprising H2O; (b) an oil phase or an oil shell, dispersed in the continuous aqueous phase; and (c) a hydrophilic polymer, stabilizing an interface between the continuous aqueous phase and the oil phase or the oil shell to form the water-in-oil-in-water (W/O/W) emulsion. The oil phase or the oil shell comprises: (i) oil; (ii) an internal aqueous phase, dispersed within the oil or the oil shell; and (iii) a lipophilic sorbitan-polyester conjugate, stabilizing an interface between the oil and the inner aqueous phase to form a water-in-oil (W/O) emulsion. The lipophilic sorbitan-polyester conjugate comprises: (1) sorbitan; and (2) poly(lactide-co-?-caprolactone) or polylactic acid (polylactide), conjugated to the sorbitan.