Patents by Inventor Hsin-Wu Mi

Hsin-Wu Mi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250044315
    Abstract: A pipette-tip connecting device has a base, a first positioning mechanism, a second positioning mechanism, a connecting seat, a pipette-fixing seat, and a tilt actuator. The first positioning mechanism extends along a first direction. The second positioning mechanism is linked to the first slider and extending upward and downward along a second direction. The connecting seat is mounted on the second slider such that positions of the connecting seat along the first direction and the second direction are controlled by the first positioning mechanism and the second positioning mechanism respectively. The pipette-fixing seat is mounted on the connecting seat and is pivotal relative to the connecting seat. The pipette-fixing seat has a pipette-tip connector which moves in the first direction and the second direction when the pipette-fixing seat pivots. The tilt actuator controls a relative angle between the pipette-fixing seat and the connecting seat.
    Type: Application
    Filed: October 18, 2024
    Publication date: February 6, 2025
    Inventors: HSIN WU MI, HSIN FEI HUANG
  • Publication number: 20240247225
    Abstract: A gravitational liquid-splitting device has a funnel, a dispensing valve, a liquid-splitting part, and a stirring assembly. The funnel has an inner space and a bottom opening connected to each other. The dispensing valve is mounted to the funnel and is configured to close or open the bottom opening of the funnel. The liquid-splitting part is connected to a bottom of the funnel and has an input channel and two output channels. The input channel is formed in the liquid-splitting part and extends upward and downward. An upper end of the input channel forms an input opening on a top of the liquid-splitting part and is connected to the bottom opening of the funnel. The stirring assembly has a stirrer configured to stir liquid in the funnel. Therefore, the gravitational liquid-splitting device improves efficiency and quality, and also reduces risk of contamination in the cell passaging operation.
    Type: Application
    Filed: January 19, 2023
    Publication date: July 25, 2024
    Inventors: HSIN-WU MI, CHIH-HUANG LIN, HSIN-FEI HUANG, CHIA-I HSU
  • Publication number: 20240206457
    Abstract: A cryopreservation cartridge has a frame and multiple cryopreservation trays. The frame has multiple mounting walls. Any two of the mounting walls have multiple tray shelf segments formed therebetween. The cryopreservation trays are respectively and detachably mounted on the tray shelf segments. Each of the cryopreservation trays has multiple cryovial mounting holes. Each of the cryovial mounting holes is adapted to load a cryovial. The cryopreservation cartridge is assembled by a frame and multiple cryopreservation trays so that one cryopreservation tray can be detached from the frame and held by a picker and then a mechanical arm can easily access any single cryovial loaded in the cryopreservation tray, thereby facilitating process of placing in or taking out the cryovial for automatic operation of cell cryopreservation and thawing.
    Type: Application
    Filed: December 21, 2022
    Publication date: June 27, 2024
    Inventors: HSIN-WU MI, CHIH-HUANG LIN, HSIN-FEI HUANG, CHIA-I HSU
  • Publication number: 20240050888
    Abstract: A carbon dioxide purification system for the treatment of a waste gas produced by a generator includes a water removal unit having at least one drying device, and a purification unit having a plurality of pressure swing adsorption devices disposed and connected in series with each other. The at least one drying device is used to reduce water vapor in the waste gas and to form a dry gas mixture having carbon dioxide gas. The pressure swing adsorption devices are used to purify carbon dioxide gas from the dry gas mixture, so as to obtain a gas product containing carbon dioxide gas with a purity of more than 99.5%.
    Type: Application
    Filed: July 12, 2023
    Publication date: February 15, 2024
    Inventors: Hsin-Wu MI, Chao-Kang CHANG, Hsin-Tsai WANG, Chang-Hung TU, Zih-Cian KUO
  • Publication number: 20240026336
    Abstract: A nucleic acid extraction device for molecular testing comprises a film-flipping mechanism, a cap mechanism, a dispensing mechanism, an extraction plate transfer mechanism, and a nucleic acid extraction module. A sealing film is adhered onto top of an extraction plate and folded along an outer edge of the extraction plate. A film-flipping head of the film-flipping mechanism abuts against a bottom surface of the extraction plate and pushes an edge of the sealing film to unfold the sealing film. A film gripper clamps and removes the unfolded sealing film. The cap mechanism opens the specimen containers. The dispensing mechanism transfers the specimens from the specimen containers to the extraction plate. The extraction plate transfer mechanism moves the extraction plate with the specimens to the nucleic acid extraction module. As a result, molecular testing is automated to reduce labor and improve quality.
    Type: Application
    Filed: July 21, 2022
    Publication date: January 25, 2024
    Inventors: Hsin-Wu MI, Hsin-Fei HUANG
  • Patent number: 11761974
    Abstract: A cell and medicament dispensing device for drug screening is configured to dispense minute amount of cells and medicaments. The device has a base, a transfer plate serving mechanism, a transfer plate positioning mechanism, an injection mechanism, a cell culture plate positioning mechanism, and a dispensing mechanism. The transfer plate serving mechanism moves a transfer plate to the transfer plate positioning mechanism. The injection mechanism injects cells and medicaments into recesses in the transfer plate. A cell culture plate is fixed in the cell culture plate positioning mechanism. The dispensing mechanism moves back and forth between a position above the transfer plate and a position above the cell culture plate to dispense the cells or medicaments from the transfer plate to the cell culture plate. As a result, the process of drug screening is automated to reduce labor and improve quality significantly.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: September 19, 2023
    Assignee: DrSignal BioTechnology Co., Ltd.
    Inventors: Hsin Wu Mi, Hsin Fei Huang
  • Patent number: 11744242
    Abstract: A living body specimen transport device for receiving multiple living body specimens has a frame, a rotating bracket, and a storage assembly. The rotating bracket can be rotated with respect to the frame. The storage assembly can receive a container with a living body specimen and be rotated with respect to the rotating bracket. A center of gravity of the storage assembly is lower than a pivoting point where the rotating bracket is mounted on the frame and a pivoting point where the storage assembly is mounted on the rotating bracket. With such structure, even when the living body specimen transport device is vibrated and shaken during transporting and then the frame of the living body specimen transport device is tilted or turned over, the rotating bracket and the storage assembly can rotate to be vertical by themselves, which keeps the living body specimen being soaked in the preservation solution.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: September 5, 2023
    Assignee: DRSIGNAL BIOTECHNOLOGY CO., LTD.
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee, Jen-Sheng Hsu
  • Publication number: 20230133990
    Abstract: A pipette-tip connecting device has a base, a first positioning mechanism, a second positioning mechanism, a connecting seat, a pipette-fixing seat, and a tilt actuator. The first positioning mechanism extends along a first direction. The second positioning mechanism is linked to the first slider and extending upward and downward along a second direction. The connecting seat is mounted on the second slider such that positions of the connecting seat along the first direction and the second direction are controlled by the first positioning mechanism and the second positioning mechanism respectively. The pipette-fixing seat is mounted on the connecting seat and is pivotal relative to the connecting seat. The pipette-fixing seat has a pipette-tip connector which moves in the first direction and the second direction when the pipette-fixing seat pivots. The tilt actuator controls a relative angle between the pipette-fixing seat and the connecting seat.
    Type: Application
    Filed: November 1, 2021
    Publication date: May 4, 2023
    Inventors: HSIN WU MI, HSIN FEI HUANG
  • Publication number: 20230135251
    Abstract: A cell and medicament dispensing device for drug screening is configured to dispense minute amount of cells and medicaments. The device has a base, a transfer plate serving mechanism, a transfer plate positioning mechanism, an injection mechanism, a cell culture plate positioning mechanism, and a dispensing mechanism. The transfer plate serving mechanism moves a transfer plate to the transfer plate positioning mechanism. The injection mechanism injects cells and medicaments into recesses in the transfer plate. A cell culture plate is fixed in the cell culture plate positioning mechanism. The dispensing mechanism moves back and forth between a position above the transfer plate and a position above the cell culture plate to dispense the cells or medicaments from the transfer plate to the cell culture plate. As a result, the process of drug screening is automated to reduce labor and improve quality significantly.
    Type: Application
    Filed: November 1, 2021
    Publication date: May 4, 2023
    Inventors: HSIN WU MI, HSIN FEI HUANG
  • Publication number: 20220079141
    Abstract: A living body specimen transport device for receiving multiple living body specimens has a frame, a rotating bracket, and a storage assembly. The rotating bracket can be rotated with respect to the frame. The storage assembly can receive a container with a living body specimen and be rotated with respect to the rotating bracket. A center of gravity of the storage assembly is lower than a pivoting point where the rotating bracket is mounted on the frame and a pivoting point where the storage assembly is mounted on the rotating bracket. With such structure, even when the living body specimen transport device is vibrated and shaken during transporting and then the frame of the living body specimen transport device is tilted or turned over, the rotating bracket and the storage assembly can rotate to be vertical by themselves, which keeps the living body specimen being soaked in the preservation solution.
    Type: Application
    Filed: September 17, 2020
    Publication date: March 17, 2022
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee, Jen-Sheng Hsu
  • Patent number: 11142733
    Abstract: A culture flask has a flask body. The flask body has two translucent planes, one opening end, one recess end and at least one collecting recess. Both translucent planes are located on the opposite ends of the flask body. A collecting recess is formed on the inner surface of the recess end, while the cross sectional area of the recess end gradually decreases toward the bottom of the collecting recess. By forming a collecting recess with decreased cross sectional area, culture cells can be collected inside the bottom after centrifugation, and therefore the user no longer has to transfer the culture cells and culture medium to a centrifuge tube when replacing culture medium. Consumption of suction tube and centrifuge tube can be avoided, the time to replace the culture medium is reduced, and also the risk of contamination when replacing the culture medium is reduced.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: October 12, 2021
    Assignee: SCL BIOTECH LTD.
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee
  • Patent number: 10835896
    Abstract: Provided are a cell dispensing and storing apparatus and a method of the same. The method includes: moving a freezing container with a test tube in it and a temporary storage bottle containing sample cells into a dispensing area. Connect the temporary storage bottle with an injecting assembly. A dispensing clamp moves the test tube from the freezing container to a tube rack on a rotating platform. A rotating clamp removes a tube cover from the test tube. An injecting nozzle extracts the sample cells from the temporary storage bottle and dispenses the sample cells into the test tube. The rotating clamp puts the tube cover back on the test tube. The dispensing clamp moves the test tube back into the freezing container. A freezing clamp moves the freezing container into a freezer.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: November 17, 2020
    Assignee: SCL BIOTECH LTD.
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee
  • Patent number: 10746633
    Abstract: Provided is a tissue slicing device having a first motor, a filling assembly, a filter, a pipe, and a cutter. The filling assembly includes a tube and a piston rod movably inserted through the tube. One end of the piston rod abuts against the first motor. The filter is located at an end of the tube opposite the first motor. The pipe is located at a common side of the first motor and the filling assembly, and includes a nozzle located at an end of the pipe and proximal to an end of the filter opposite the filling assembly. The cutter is proximal to the filter. The guiding body is located at the end of the tube opposite the first motor. Provided is an apparatus having the tissue slicing device, such that manpower and time can be saved, and the tissue slicing degree can be unified.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: August 18, 2020
    Assignee: SCL Biotech Ltd.
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee
  • Publication number: 20200123486
    Abstract: A culture flask has a flask body. The flask body has two transparent planes, one opening end, one recess end and at least one collecting recess. Both transparent planes are located on the opposite ends of the flask body. A collecting recess is formed on the inner surface of the recess end, while the cross sectional area of the recess end gradually decreases toward the bottom of the collecting recess. By forming a collecting recess with decreased cross sectional area, culture cells can be collected inside the bottom after centrifugation, and therefore the user no longer has to transfer the culture cells and culture medium to a centrifuge tube when replacing culture medium. Consumption of suction tube and centrifuge tube can be avoided, the time to replace the culture medium is reduced, and also the risk of contamination when replacing the culture medium is reduced.
    Type: Application
    Filed: January 16, 2019
    Publication date: April 23, 2020
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee
  • Publication number: 20200114344
    Abstract: Provided are a cell dispensing and storing apparatus and a method of the same. The method includes: moving a freezing container with a test tube in it and a temporary storage bottle containing sample cells into a dispensing area. Connect the temporary storage bottle with an injecting assembly. A dispensing clamp moves the test tube from the freezing container to a tube rack on a rotating platform. A rotating clamp removes a tube cover from the test tube. An injecting nozzle extracts the sample cells from the temporary storage bottle and dispenses the sample cells into the test tube. The rotating clamp puts the tube cover back on the test tube. The dispensing clamp moves the test tube back into the freezing container. A freezing clamp moves the freezing container into a freezer.
    Type: Application
    Filed: October 10, 2018
    Publication date: April 16, 2020
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee
  • Patent number: 10528997
    Abstract: A system includes an online shopping platform, a ingredient database assembly and a control unit. The control unit transmits to the online shopping platform entries of active ingredient data and preservative ingredient data respectively corresponding to an active ingredient and a preservative ingredient and respectively stored in an active ingredient database and a preservative ingredient database of the ingredient database assembly, for allowing selection of at least one of the entries via the online shopping platform to result in a desired formula. The desired formula is used for subsequent production of a customized ingredient composition when it is determined that the desired formula conforms with rules of formulation.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: January 7, 2020
    Assignee: DRSIGNAL BIOTECHNOLOGY CO., LTD.
    Inventors: Hsin-Wu Mi, Yuan-Ting Chuang, Ming-Cheng Lee, Ting-Chieh Lin, Yi-Hao Huang
  • Publication number: 20180240175
    Abstract: A system includes an online shopping platform, a ingredient database assembly and a control unit. The control unit transmits to the online shopping platform entries of active ingredient data and preservative ingredient data respectively corresponding to an active ingredient and a preservative ingredient and respectively stored in an active ingredient database and a preservative ingredient database of the ingredient database assembly, for allowing selection of at least one of the entries via the online shopping platform to result in a desired formula. The desired formula is used for subsequent production of a customized ingredient composition when it is determined that the desired formula conforms with rules of formulation.
    Type: Application
    Filed: November 10, 2017
    Publication date: August 23, 2018
    Inventors: Hsin-Wu MI, Yuan-Ting CHUANG, Ming-Cheng LEE, Ting-Chieh LIN, Yi-Hao HUANG
  • Publication number: 20180231438
    Abstract: Provided is a tissue slicing device having a motor component, a filling component, a filter, a pipe, and a cutting component. The filling component includes a tube and a piston rod movably inserted through the tube. One end of the piston rod abuts against the motor component. The filter is located at an end of the tube opposite the motor component. The pipe is located at a common side of the motor component and the filling component, and includes a nozzle located at an end of the pipe and proximal to an end of the filter opposite the filling component. The cutting component is proximal to the filter. The guiding body is located at the end of the tube opposite the motor component. Provided is an apparatus having the tissue slicing device, such that manpower and time can be saved, and the tissue slicing degree can be unified.
    Type: Application
    Filed: March 31, 2017
    Publication date: August 16, 2018
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee
  • Patent number: 9850459
    Abstract: Provided is a primary cell isolating apparatus that includes, sequentially adjacent, a slicing space, a working space, a picking space, and a sliding device mounted through the above spaces. The slicing space has a slicing device. The working space has a first gate, a heater, a rotating holder, a centrifuge, an open-close cap device, a tube rack, and a liquid transferring device. The first gate is adjacent to the slicing space. The heater is proximal to the first gate, and is sequentially adjacent to the rotating holder and the centrifuge. The open-close cap device is proximal to the first gate and is opposite the heater, and is sequentially adjacent to the tube rack and the liquid transferring device. The picking space has a second gate adjacent to the working space. Also provided is a method of using the primary cell isolating apparatus as abovementioned for saving manpower.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: December 26, 2017
    Assignee: SCL Biotech Ltd.
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee
  • Patent number: 9828579
    Abstract: A cell culture apparatus comprises at least one storage space, at least one barrier, a working space, a sterilization space, and a control space. The at least one storage space comprises a container shelf, an upright track, a rotatable holder, and a light tube. The working space comprises a filling station and an inspecting station. The filling station comprises a first delivering device, an open-close device, and a filling mechanism. The inspecting station comprises a first inspecting mechanism and a second delivering device. Also provided is a method of using the cell culture apparatus including steps of filling, inspecting, or collecting cell cultures, therefore, the cell culture apparatus performs multiple cell culture processes automatically.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: November 28, 2017
    Assignee: DrSignal BioTechnology co., Ltd
    Inventors: Hsin-Wu Mi, Ming-Cheng Lee