Patents by Inventor Hsin-Yi Hsu

Hsin-Yi Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250129316
    Abstract: This disclosure relates to a biological tissue forming method includes the following steps: providing a biological tissue forming package with a base, a membrane, a sliding assembly and a sealing film that seals a chamber of the base used for receiving the membrane and the sliding assembly with one of the base and the sealing film being light-transmitting; passing a biological tissue fluid through the sealing film and the sliding assembly so as to be dispensed on the membrane; moving the sliding assembly away from a covering position used for covering the membrane via at least one passive magnetic element so as to expose the biological tissue fluid on the membrane; and emitting the biological tissue fluid exposed on the membrane by a curing light transmitting through the one of the base and the sealing film so as to cure the biological tissue fluid into a biological tissue.
    Type: Application
    Filed: December 15, 2023
    Publication date: April 24, 2025
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chao-Hong HSU, Teng-Yen WANG, Yang-Cheng LIN, Hsin-Yi HSU, Yu-Bing LIOU, Chang-Chou LI, Chih-Hung HUANG, Tung-Ying LIN, Li-Hsin LIN, Yuchi WANG, Hsin-Hsin SHEN
  • Patent number: 12258546
    Abstract: A cell and tissue sheet forming package includes a container body, a membrane, a sliding door plate and a sealing film. The sliding door plate is disposed slidably on a top of the container body to cover or expose the membrane. The sliding door plate has a hole and a passive magnetic assembly. The cell injection equipment includes a carrier, an injection mechanism and a drive mechanism. The carrier carries the package, and the drive mechanism moves the carrier and the injection mechanism to have the injection mechanism to inject a solution, through the hole, into the package. A heating element of the carrier is introduced to heat the membrane and the solution to transform the solution into a colloid sheet on the membrane. Then, the positive magnetic assembly engages magnetically the passive magnetic assembly to slide the sliding door plate to expose the colloid sheet on the membrane.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: March 25, 2025
    Assignee: Industrial Technology Research Institute
    Inventors: Hsin-Yi Hsu, Yang-Cheng Lin, Chao-Hong Hsu, Yu-Bing Liou, Li-Hsin Lin, Hsin-Hsin Shen, Yu-Chi Wang, Chang-Chou Li, Chih-Hung Huang
  • Patent number: 12054612
    Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: August 6, 2024
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yun-Chung Teng, Jen-Huang Huang, Ying-Wen Shen, Yu-Bing Liou, Hsin-Yi Hsu, Li-Hsin Lin, Yuchi Wang, Hsin-Hsin Shen
  • Publication number: 20240217109
    Abstract: An automated transport vehicle for transporting an article includes a carrying seat, a mechanical arm and a holding mechanism. The holding mechanism includes at least one first positioning post and at least one second positioning post and, when the holding mechanism holds the article, the first positioning post is in contact with a side surface of the article, and the second positioning post is in contact with a bottom surface of the article.
    Type: Application
    Filed: November 28, 2023
    Publication date: July 4, 2024
    Inventors: Chien-Wei CHEN, Hsin-Yi HSU, Shiang-Fu LIN
  • Patent number: 11904581
    Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer, and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution is 1:0.01-1. Moreover, the second polymer solution is composed of a second hydrophilic solution.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: February 20, 2024
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hsin-Hsin Shen, Yu-Chi Wang, Ming-Chia Yang, Yu-Bing Liou, Wei-Hong Chang, Yun-Han Lin, Hsin-Yi Hsu, Yun-Chung Teng, Chia-Jung Lu, Yi-Hsuan Lee, Jian-Wei Lin, Kun-Mao Kuo, Ching-Mei Chen
  • Publication number: 20230203415
    Abstract: A cell and tissue sheet forming package includes a container body, a membrane, a sliding door plate and a sealing film. The sliding door plate is disposed slidably on a top of the container body to cover or expose the membrane. The sliding door plate has a hole and a passive magnetic assembly. The cell injection equipment includes a carrier, an injection mechanism and a drive mechanism. The carrier carries the package, and the drive mechanism moves the carrier and the injection mechanism to have the injection mechanism to inject a solution, through the hole, into the package. A heating element of the carrier is introduced to heat the membrane and the solution to transform the solution into a colloid sheet on the membrane. Then, the positive magnetic assembly engages magnetically the passive magnetic assembly to slide the sliding door plate to expose the colloid sheet on the membrane.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 29, 2023
    Inventors: HSIN-YI HSU, YANG-CHENG LIN, CHAO-HONG HSU, YU-BING LIOU, LI-HSIN LIN, HSIN-HSIN SHEN, YU-CHI WANG, CHANG-CHOU LI, CHIH-HUNG HUANG
  • Publication number: 20220388293
    Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer, and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution is 1:0.01-1. Moreover, the second polymer solution is composed of a second hydrophilic solution.
    Type: Application
    Filed: August 11, 2022
    Publication date: December 8, 2022
    Applicant: Industrial Technology Research Institute
    Inventors: Hsin-Hsin SHEN, Yu-Chi WANG, Ming-Chia YANG, Yu-Bing LIOU, Wei-Hong CHANG, Yun-Han LIN, Hsin-Yi HSU, Yun-Chung TENG, Chia-Jung LU, Yi-Hsuan LEE, Jian-Wei LIN, Kun-Mao KUO, Ching-Mei CHEN
  • Patent number: 11458715
    Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer; and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution is 1:0.01-1. Moreover, the second polymer solution consists of a second hydrophilic solution.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: October 4, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hsin-Hsin Shen, Yu-Chi Wang, Ming-Chia Yang, Yu-Bing Liou, Wei-Hong Chang, Yun-Han Lin, Hsin-Yi Hsu, Yun-Chung Teng, Chia-Jung Lu, Yi-Hsuan Lee, Jian-Wei Lin, Kun-Mao Kuo, Ching-Mei Chen
  • Publication number: 20220204772
    Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 30, 2022
    Applicant: Industrial Technology Research Institute
    Inventors: Yun-Chung TENG, Jen-Huang HUANG, Ying-Wen SHEN, Yu-Bing LIOU, Hsin-Yi HSU, Li-Hsin LIN, Yuchi WANG, Hsin-Hsin SHEN
  • Publication number: 20220204936
    Abstract: A non-fibrous film of which the composition includes a collagen and a polyester polymer is provided. A content of the polyester polymer in the non-fibrous film is 1-60 wt %. Moreover, the non-fibrous film has a swelling rate of 1-200 ?m/hour or a swelling proportion per unit time of 0.1-2%/hour in an aqueous liquid.
    Type: Application
    Filed: September 15, 2021
    Publication date: June 30, 2022
    Applicant: Industrial Technology Research Institute
    Inventors: Yu-Bing LIOU, Chih-Ching LIAO, Hsin-Yi HSU, Ying-Wen SHEN, Yun-Chung TENG, Hsin-Hsin SHEN, Yi-Chen CHEN
  • Patent number: 11103446
    Abstract: An ophthalmic drug delivery device and a method for fabricating the same are provided. The ophthalmic drug delivery device includes a shield element and a drug release element. The shield element has a light transmittance more than or equal to 80%. The drug release element is an annular body so that the drug release element surrounds the shield element. The drug release element is neutral and includes a cross-linked neutral collagen, a first hydrophilic biodegradable polymer and a drug. The shield element is acidic and includes a cross-linked acidic collagen and a second hydrophilic biodegradable polymer.
    Type: Grant
    Filed: December 31, 2019
    Date of Patent: August 31, 2021
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu-Bing Liou, Hsin-Yi Hsu, Ying-Wen Shen, Yun-Chung Teng, Yuchi Wang, Hsin-Hsin Shen
  • Publication number: 20210196626
    Abstract: An ophthalmic drug delivery device and a method for fabricating the same are provided. The ophthalmic drug delivery device includes a shield element and a drug release element. The shield element has a light transmittance more than or equal to 80%. The drug release element is an annular body so that the drug release element surrounds the shield element. The drug release element is neutral and includes a cross-linked neutral collagen, a first hydrophilic biodegradable polymer and a drug. The shield element is acidic and includes a cross-linked acidic collagen and a second hydrophilic biodegradable polymer.
    Type: Application
    Filed: December 31, 2019
    Publication date: July 1, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Yu-Bing LIOU, Hsin-Yi HSU, Ying-Wen SHEN, Yun-Chung TENG, Yuchi WANG, Hsin-Hsin SHEN
  • Patent number: 10918474
    Abstract: An implanting device is used for implanting a membrane in a biological tissue. The implanting device includes a sleeve, a membrane storage element, an injection element and a bubble generating element. The membrane storage element is fixed at the sleeve. The injection element is inserted in the sleeve and the membrane storage element, and includes a capturing end and connecting end. The capturing end is for capturing the membrane and has a hole. The bubble generating element is connected to the connecting end, and is for providing a gas that is then outputted via the hole. By the rotation of the injection element, the capturing end extends straight out of the membrane storage element or retracts straight into the membrane storage element.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: February 16, 2021
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu-Bing Liou, Ming-Chia Yang, Hsin-Yi Hsu, Yun-Han Lin, Wei-Hong Chang, I-Jong Wang, Hsin-Hsin Shen
  • Publication number: 20200247101
    Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer; and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution 1:0.01-1. Moreover, the second polymer solution consists of a second hydrophilic solution.
    Type: Application
    Filed: November 6, 2019
    Publication date: August 6, 2020
    Applicant: Industrial Technology Research Institute
    Inventors: Hsin-Hsin SHEN, Yu-Chi WANG, Ming-Chia YANG, Yu-Bing LIOU, Wei-Hong CHANG, Yun-Han LIN, Hsin-Yi HSU, Yun-Chung TENG, Chia-Jung LU, Yi-Hsuan LEE, Jian-Wei LIN, Kun-Mao KUO, Ching-Mei CHEN
  • Publication number: 20200170838
    Abstract: An eye wearing device is provided, including a body, at least one reservoir and at least one microchannel. The body has a first surface, a second surface, a center, a first outer edge of the first surface and a second outer edge of the second surface. The reservoir is disposed in the body to load the drug. The microchannel is disposed near the first outer edge of the first surface and the second outer edge of the second surface. One end of the microchannel is connected to the reservoir for filling the drug into the reservoir. The other end of the microchannel is an opening facing an edge of the eye wearing device for contacting the cornea and/or the sclera, and the opening is connected to the first outer edge of the first surface and the second outer edge of the second surface.
    Type: Application
    Filed: November 14, 2019
    Publication date: June 4, 2020
    Applicant: Industrial Technology Research Institute
    Inventors: Yun-Chung Teng, Yu-Bing Liou, Hsin-Yi Hsu, Ying-Wen Shen, Sen-Lu Chen, Yu-Chi Wang, Hsin-Hsin Shen
  • Publication number: 20190076234
    Abstract: An implanting device is used for implanting a membrane in a biological tissue. The implanting device includes a sleeve, a membrane storage element, an injection element and a bubble generating element. The membrane storage element is fixed at the sleeve. The injection element is inserted in the sleeve and the membrane storage element, and includes a capturing end and connecting end. The capturing end is for capturing the membrane and has a hole. The bubble generating element is connected to the connecting end, and is for providing a gas that is then outputted via the hole. By the rotation of the injection element, the capturing end extends straight out of the membrane storage element or retracts straight into the membrane storage element.
    Type: Application
    Filed: September 5, 2018
    Publication date: March 14, 2019
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu-Bing LIOU, Ming-Chia YANG, Hsin-Yi HSU, Yun-Han LIN, Wei-Hong CHANG, I-Jong WANG, Hsin-Hsin SHEN
  • Patent number: 10143530
    Abstract: According to embodiments, a membrane with a flat or curved surface is provided for protection of intraocular tissues. The membrane can be used to cover the cornea for protecting corneal endothelial cells, to cover the anterior and posterior surface of the iris, or to cover the surface of the posterior capsule for separating the intraocular tissues. The membrane has a layered structure, which is composed of a collagen and a hydrophilic biopolymer or an organic polymer material. In particular, the membrane has high transparency and high water retention in a wet state.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: December 4, 2018
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Yu-Bing Liou, Hsiu-Ying Wang, Hsin-Yi Hsu, Wei-Li Chen, Chin-Tsung Huang, Hsin-Hsin Shen
  • Publication number: 20170172686
    Abstract: According to embodiments, a membrane with a flat or curved surface is provided for protection of intraocular tissues. The membrane can be used to cover the cornea for protecting corneal endothelial cells, to cover the anterior and posterior surface of the iris, or to cover the surface of the posterior capsule for separating the intraocular tissues. The membrane has a layered structure, which is composed of a collagen and a hydrophilic biopolymer or an organic polymer material. In particular, the membrane has high transparency and high water retention in a wet state.
    Type: Application
    Filed: July 15, 2016
    Publication date: June 22, 2017
    Applicants: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Yu-Bing LIOU, Hsiu-Ying WANG, Hsin-Yi HSU, Wei-Li CHEN, Chin-Tsung HUANG, Hsin-Hsin SHEN
  • Publication number: 20160015852
    Abstract: According to embodiments, a composite material is disclosed. The composite material has a multi-layered structure, wherein the multi-layered structure is constituted by a hydrophilic biodegradable polymer and a collagen. In particular, the collagen is strip-shaped and has a fiber length from 1.5 mm to 50 mm. There are at least ten stacked layers per 5 ?m of thickness in the multi-layered structure.
    Type: Application
    Filed: July 14, 2015
    Publication date: January 21, 2016
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu-Bing LIOU, Hsiu-Ying WANG, Hsin-Hsin SHEN, Ying-Wen SHEN, Chin-Tsung HUANG, Hsin-Yi HSU
  • Patent number: 8969593
    Abstract: Organic dyes and photoelectric conversion devices are provided. The Organic dye has the structure represented by formula (I), wherein, n is an integral of 2-11; the plurality of X is independent and elected from the group consisting of and combinations thereof; R, R1, and R2 comprise hydrogen, halogen, C1-18 alkyl group, C1-18 alkoxy group, C3-18 heteroalkyl group, C3-20 aryl group, C3-20 heteroaryl group, C3-20 cycloaliphatic group or C3-20 cycloalkyl group, or R1 is connected to R2 to form a ring having 5-14 members; R3 comprise hydrogen, halogen, nitro group, amino group, C1-18 alkyl group, C1-18 alkoxy group, C1-18 sulfanyl group, C3-18 heteroalkyl group, C3-20 aryl group, C3-20 heteroaryl group, C3-20 cycloaliphatic group or C3-20 cycloalkyl group; and Z is hydrogen, alkali metal, or quaternary ammonium salt.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: March 3, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Yung-Liang Tung, Jia-Yin Wu, Jen-An Chen, Hsin-Yi Hsu, Chun-Guey Wu, Min-Fong Jhong, Song-Yeu Tsai