Patents by Inventor Hsin-Yi Hung

Hsin-Yi Hung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of curcuminoids and use thereof as an anticancer agent
    Patent number: 10787413
    Abstract: A series of novel bis(hydroxymethyl) alkanoate derivatives of curcuminoids were designed, and synthesized, which show anticancer activity, and in particular to breast cancer, colon cancer, and prostate cancer.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: September 29, 2020
    Assignee: CHINA MEDICAL UNIVERSITY
    Inventors: Sheng-Chu Kuo, Kuo-Hsiung Lee, Chang-Hai Tsai, Min-Tsang Hsieh, Ling-Chu Chang, Hsin-Yi Hung, Hui-Yi Lin, Jai-Sing Yang
  • NOVEL DERIVATIVES OF CURCUMINOIDS AND USE THEREOF AS AN ANTICANCER AGENT
    Publication number: 20190161430
    Abstract: A series of novel bis(hydroxymethyl) alkanoate derivatives of curcuminoids were designed, and synthesized, which show anticancer activity, and in particular to breast cancer, colon cancer, and prostate cancer.
    Type: Application
    Filed: June 2, 2017
    Publication date: May 30, 2019
    Inventors: SHENG-CHU KUO, KUO-HSIUNG LEE, CHANG-HAI TSAI, MIN-TSANG HSIEH, LING-CHU CHANG, HSIN-YI HUNG, HUI-YI LIN, JAI-SING YANG
  • 20()-sulfonylamidine derivatives of camptothecin and the use thereof as a potent antitumor agent
    Patent number: 9718835
    Abstract: The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: August 1, 2017
    Assignees: CHINA MEDICAL UNIVERSITY HOSPITAL, THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Kuo-Hsiung Lee, Keduo Qian, Xiaoming Yang, Masuo Goto, Ying-Qian Liu, Yong-Long Zhao, Liu Yang, Mei-Juan Wang, Zhi-Jun Zhang, Tian-Shung Wu, Che-Ming Teng, Chih-Ya Wang, Shiow-Lin Pan, Sheng-Chu Kuo, Hsin-Yi Hung, Ling-Chu Chang, Yang-Chang Wu, Min-Tsang Hsieh, Chung Y. Hsu, Woei-Cherng Shyu, Chen-Huan Lin
  • NOVEL 20(S)-SULFONYLAMIDINE DERIVATIVES OF CAMPTOTHECIN AND THE USE THEREOF AS A POTENT ANTITUMOR AGENT
    Publication number: 20160229862
    Abstract: The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
    Type: Application
    Filed: September 26, 2014
    Publication date: August 11, 2016
    Inventors: Kuo-Hsiung LEE, Keduo QIAN, Xiaoming YANG, Masuo GOTO, Ying-Qian LIU, Yong-Long ZHAO, Liu YANG, Mei-Juan WANG, Zhi-Jun ZHANG, Tian-Shung WU, Che-Ming TENG, Chih-Ya WANG, Shiow-Lin PAN, Sheng-Chu KUO, Hsin-Yi HUNG, Ling-Chu CHANG, Yang-Chang WU, Min-Tsang HSIEH, Chung Y. HSU, Woei-Cherng SHYU, Chen-Huan LIN
  • Vibrio harveyi-specific binding down syndrome cell adhesion molecule, method for identification thereof and use thereof
    Patent number: 9328151
    Abstract: The present invention relates to a Vibrio harveyi-specific binding Dscam of shrimps, a method for identification thereof and a use thereof. Primarily, Dscam cDNAs are prepared from V. harveyi-challenged shrimps. A database is established with various Dscam isoforms therein by means of numerous cloning and sequencing. After a phylogenetic analysis, a plurality of candidate Dscam isoforms is selected. Each recombinant protein of candidate Dscam isoforms is expressed through an expression system. Finally, the binding affinity between V. harveyi and each recombinant protein of candidate Dscam isoforms is measured to further selection of a V. harveyi-specific binding Dscam and the amino acid sequence thereof. Accordingly, the Dscam can be specifically binding to V. harveyi for eliminating or reducing V. harveyi.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: May 3, 2016
    Assignee: National Cheng Kung University
    Inventors: Han-Ching Wang, Hsin-Yi Hung, Tze-Hann Ng, Yi-An Chiang
  • Stilbenoid compound as inhibitor for squamous carcinoma and hepatoma and uses thereof
    Patent number: 9266813
    Abstract: The present invention provides a series of derivatives of stilbenoid which are useful as new inhibitory agents against head and neck squamous cell carcinoma (HNSCC) and hepatoma.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: February 23, 2016
    Assignee: China Medical University
    Inventors: Sheng-Chu Kuo, Jai-Sing Yang, Min-Tsang Hsieh, Tian-Shung Wu, Kuo-Hsiung Lee, Huei-Wen Chen, Li-Jiau Huang, Hsin-Yi Hung, Tzong-Der Way, Ling-Chu Chang, Hui-Yi Lin, Yung-Yi Cheng, Chin-Yu Liu
  • VIBRIO HARVEYI-SPECIFIC BINDING DOWN SYNDROME CELL ADHESION MOLECULE, METHOD FOR IDENTIFICATION THEREOF AND USE THEREOF
    Publication number: 20150044699
    Abstract: The present invention relates to a Vibrio harveyi-specific binding Dscam of shrimps, a method for identification thereof and a use thereof. Primarily, Dscam cDNAs are prepared from V. harveyi-challenged shrimps. A database is established with various Dscam isoforms therein by means of numerous cloning and sequencing. After a phylogenetic analysis, a plurality of candidate Dscam isoforms is selected. Each recombinant protein of candidate Dscam isoforms is expressed through an expression system. Finally, the binding affinity between V. harveyi and each recombinant protein of candidate Dscam isoforms is measured to further selection of a V. harveyi-specific binding Dscam and the amino acid sequence thereof. Accordingly, the Dscam can be specifically binding to V. harveyi for eliminating or reducing V. harveyi.
    Type: Application
    Filed: October 16, 2013
    Publication date: February 12, 2015
    Applicant: National Cheng Kung University
    Inventors: HAN-CHING WANG, HSIN-YI HUNG, TZE-HANN NG, YI-AN CHIANG
  • STILBENOID COMPOUND AS INHIBITOR FOR SQUAMOUS CARCINOMA AND HEPATOMA AND USES THEREOF
    Publication number: 20140303241
    Abstract: The present invention provides a series of derivatives of stilbenoid which are useful as new inhibitory agents against head and neck squamous cell carcinoma (HNSCC) and hepatoma.
    Type: Application
    Filed: March 28, 2014
    Publication date: October 9, 2014
    Applicant: AnnCare Bio-Tech Center Inc.
    Inventors: Sheng-Chu Kuo, Jai-Sing Yang, Min-Tsang Hsieh, Tian-Shung Wu, Kuo-Hsiung Lee, Huei-Wen Chen, Li-Jiau Huang, Hsin-Yi Hung, Tzong-Der Way, Ling-Chu Chang, Hui-Yi Lin, Yung-Yi Cheng, Chin-Yu Liu