Abstract: A wire tension control mechanism includes a wire feeding device, a connecting device and a wire guiding device. The connecting device includes a fixing element and a rotor. The fixing element is connected with the wire feeding device. The rotor is disposed on the fixing element and is movable relative to the fixing element. The wire guiding device is connected to the rotor.

Abstract: There is provided a wearable device including at least one light source, a light sensor and a processor. The processor generates a peak interval plot according to one of at least two light detection signals detected by the light sensor when the at least one light source emits light, and generates an oxygen saturation plot according to two of the one of at least two light detection signals detected by the light sensor when the at least one emits light. The processor further determines an Apnea Hypopnea Index (AHI) score according to the peak interval plot, determines an Oxygen Desaturation Index (ODI) score according to the oxygen saturation plot and fits an obstructive sleep apnea level index corresponding to the AHI score and the ODI score.

Abstract: A sprayer includes: a container; a passage including a transparent window, a first opening, a second opening and a resonator, wherein when liquid in the container is passed through the resonator via the first opening, the liquid is emitted as a gas via the second opening; and a removable detection unit disposed outside of the passage. The removable detection unit includes: a light source for illuminating the gas in the passage; an optical sensor disposed to detect a parameter of light reflected by the gas; and a processor coupled to the optical sensor for stopping the resonator from generating the gas when the parameter is below a threshold. The passage further includes a cavity disposed on a bottom surface of the passage in front of the optical sensor, wherein when the gas in the passage contacts the bottom surface, resultant water vapour will enter the cavity.

Abstract: Disclosed herein are compositions and methods with enhanced capability to produce orexin neuropeptide. The compositions are loaded in a nanocarrier for drug delivery. The composition comprises a first vector and a second vector. The first vector encodes mRNAs encoding a peptide with orexin activity is labeled with one or more capsid protein tags. The second vector encodes one or more capsid proteins and BBB-penetrating peptides. The one or more capsid proteins bind to the one or more capsid protein tags on the one or more mRNA.

Abstract: Disclosed herein are compositions and methods with enhanced capability to stimulate hair growth. The compositions are loaded in a nanocarrier for passive skin delivery. The composition comprises a first vector and a second vector. The first vector encodes one or more mRNAs. The one or more mRNAs encode a peptide with SCUBE3 activity and are labeled with one or more capsid protein tags. The second vector encodes one or more capsid proteins. The one or more capsid proteins bind to the one or more capsid protein tags on the one or more mRNA.

Abstract: A sprayer, comprising: a container, configured to contain liquid; a passage, comprising a first opening, a second opening, a resonator and a mesh, when the liquid is passed through the resonator, the liquid is emitted as a gas; a first optical sensor, configured to sense first optical data of at least portion of the mesh or at least portion of a surface of the container; and a processing circuit, configured to compute a foaming level of the mesh or of the surface according to the first optical data, and configured to determine whether the resonator should be turned off or not according to the foaming level. In another aspect, the processing circuit estimates a liquid level of the liquid but does not correspondingly turn off the resonator. By this way, the resonator may be turned on or turned off more properly and the liquid level may be more precisely estimated.

Abstract: A sprayer includes: a container arranged to contain liquid; a passage including a transparent window, a first opening, a second opening and a resonator, wherein when the liquid in the container is passed through the resonator via the first opening, the liquid is emitted as a gas via the second opening; and a detection unit disposed outside of the passage. The detection unit includes: a light source disposed to emit light through the light transparent window for illuminating the gas in the passage such that the gas will reflect the emitted light; an optical sensor disposed to detect a parameter of the reflected light through the transparent window; and a processor coupled to the optical sensor for stopping the resonator from generating the gas when the parameter of the reflected light is below a first threshold corresponding to a specific level of liquid within the container.

Abstract: Disclosed herein are compositions and methods with enhanced capability to reduce uric acid concentration. The compositions are loaded in a nanocarrier for oral drug delivery. The composition comprises a first vector and a second vector. The first vector encodes one or more mRNAs. The one or more mRNAs encode a peptide with uricase activity and are labeled with one or more capsid protein tags. The second vector encodes one or more capsid proteins. The one or more capsid proteins bind to the one or more capsid protein tags on the one or more mRNA.

Abstract: Disclosed herein are compositions and methods with enhanced capability to control blood sugar levels. The compositions are loaded in a nanocarrier for oral drug delivery. The composition comprises a first vector and a second vector. The first vector encodes one or more mRNAs. The one or more mRNAs encode a peptide with GLP-1 activity and are labeled with one or more capsid protein tags. The second vector encodes one or more capsid proteins. The one or more capsid proteins bind to the one or more capsid protein tags on the one or more mRNAs.

Abstract: A substance concentration measuring device, for measuring a substance concentration for a target substance in blood of a subject, comprising: a processing circuit; and a plurality of electrodes. At least two of the electrodes touches the subject when the subject wears the substance concentration measuring device, thereby the processing circuit can acquire at least one physiological signal caused by an eye of the subject. The processing circuit computes a voltage value or a voltage difference of the physiological signal, and computes the substance concentration according to the voltage value or the voltage difference. A human condition monitoring system comprising the substance concentration measuring device is also disclosed.

Abstract: A visible-light-image physiological monitoring system with thermal detecting assistance is disclosed. The system takes a visible-light image and a thermal image of a body at the same time. A processing unit identifies a body feature of the visible-light image and determines a coordinate of the feature. In a learning mode, an initial temperature of the body feature is determined from the thermal image according to the coordinate of the body feature. After then, a physiological status monitoring mode is executed to monitor the temperature changes of the body feature and output an alarm when the temperature is determined to be abnormal. Therefore, a monitoring accuracy of the visible-light-image physiological monitoring system is increased and avoids transmitting false alarms or no alarms.

Abstract: A sprayer includes: a container; a passage including a transparent window, a first opening, a second opening and a resonator, wherein when liquid in the container is passed through the resonator via the first opening, the liquid is emitted as a gas via the second opening; and a removable detection unit disposed outside of the passage. The removable detection unit includes: a light source for illuminating the gas in the passage; an optical sensor disposed to detect a parameter of light reflected by the gas; and a processor coupled to the optical sensor for stopping the resonator from generating the gas when the parameter is below a threshold. The passage further includes a cavity disposed on a bottom surface of the passage in front of the optical sensor, wherein when the gas in the passage contacts the bottom surface, resultant water vapour will enter the cavity.

Abstract: An exosomal nucleic acid extraction method is provided. A substrate is provided, on which antibodies and silicon nanoparticles are disposed, and the antibodies have binding specificity to exosomal surface antigens. After that, based on the binding specificity between the antibodies and the exosomal surface antigens, exosomes in a specimen are separated. Next, the nucleic acids in the separated exosomes are adsorbed by the silicon nanoparticles.

Abstract: An optical image physiological monitoring system with radar detection assistance is disclosed. The system receives a visible-light image of a body and then identifies a chest feature of the visible-light image and determines a position of the chest feature. A processing unit controls a radar detector to move to aim a chest of the body. After then, a plurality of visible-light images and distance values from the radar detector are received continuously to determine whether the positions of the chest features are in a position change rage. If yes, a breathing frequency of the body is determined by the distance values received simultaneously.

Abstract: An image detection method for selecting a representative image of a user is provided. In the image detection method, a plurality of images of the user are obtained, and a plurality of feature parameters of the plurality of images are obtained. A face occlusion analysis is performed on the plurality of images according to the plurality of feature parameters to determine whether the plurality of images clearly show the user's face. A plurality of feature vectors are determined, and a body distribution analysis is performed on the plurality of images according to the plurality of feature vectors to determine a body position and a position type of the user. An image related to the position type is selected according to results of the face occlusion analysis and the body distribution analysis.

Abstract: A visible-light-image physiological monitoring system with thermal detecting assistance is disclosed. The system takes a visible-light image and a thermal image of a body at the same time. A processing unit identifies a body feature of the visible-light image and determines a coordinate of the feature. In a learning mode, an initial temperature of the body feature is determined from the thermal image according to the coordinate of the body feature. After then, a physiological status monitoring mode is executed to monitor the temperature changes of the body feature and output an alarm when the temperature is determined to be abnormal. Therefore, a monitoring accuracy of the visible-light-image physiological monitoring system is increased and avoids transmitting false alarms or no alarms.

Abstract: An optical medical detection device includes a first physiological sensor and a processor. The first physiological sensor is adapted to continuously output a first photoplethysmography (PPG) signal generated by a first skin area of an object, and further to optionally and continuously output a second photoplethysmography (PPG) signal generated by a second skin area of the object. The second skin area is different from the first skin area. The processor is electrically connected to the first physiological sensor. The processor is adapted to convert the first PPG signal and the second PPG signal into a physiological feature, and the physiological feature is at least one of a blood pressure ratio and a blood flow velocity.

Abstract: An image detection method is provided. In the image detection method, images of a user are obtained, feature parameters are marked in the images, and detection results of the feature parameters in each of the images are evaluated. A body distribution analysis is performed on the images according to the detection result of at least one first feature parameter among the feature parameters to determine first position information of the user. A face occlusion analysis is performed on the images according to the detection result of at least one second feature parameter among the feature parameters and the first position information to determine second position information of the user. The at least one second feature parameter is different from the at least one first feature parameter. The second position information represents a position of the user.