Patents by Inventor Hsing-Mao CHU

Hsing-Mao CHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide core-based multi-arm linkers for treating infectious diseases
    Patent number: 9994638
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: June 12, 2018
    Inventors: Tse-Wen Chang, Hsing-Mao Chu, Chien-Jen Lin, Chun-Yu Lin
  • Peptide core-based multi-arm linkers for treating central nervous system diseases
    Patent number: 9988454
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: June 5, 2018
    Inventors: Tse-Wen Chang, Hsing-Mao Chu, Chien-Jen Lin, Chun-Yu Lin
  • Peptide core-based multi-arm linkers and their applications
    Patent number: 9975951
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: May 22, 2018
    Inventors: Tse-Wen Chang, Hsing-Mao Chu
  • MULTI-ARM LINKERS FOR CONSTRUCTING PHARMACEUTICAL MOLECULES
    Publication number: 20180110872
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: October 23, 2017
    Publication date: April 26, 2018
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU, Chia-Chun CHEN
  • Peptide core-based multi-arm linkers
    Patent number: 9907858
    Abstract: The present disclosure provides various molecular constructs having a targeting element and/or an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Grant
    Filed: January 18, 2016
    Date of Patent: March 6, 2018
    Inventors: Tse-Wen Chang, Hsing-Mao Chu
  • VERSATILE PEPTIDE-BASED MULTI-ARM LINKERS FOR CONSTRUCTING PHARMACEUTICAL MOLECULES
    Publication number: 20180055946
    Abstract: Disclosed herein are linker units comprising a center core, a plurality of linking arms, and optionally, a coupling arm. According to the embodiments of the present disclosure, the present linker units further comprises a targeting element and an effector element. Also disclosed herein are methods for treating various diseases using such linker units.
    Type: Application
    Filed: September 1, 2017
    Publication date: March 1, 2018
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU
  • Anti-inflammatory molecules with tissue-targeting functions
    Publication number: 20180044437
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating osteoporosis using such molecular constructs are also disclosed.
    Type: Application
    Filed: October 2, 2017
    Publication date: February 15, 2018
    Applicant: Academia Sinica
    Inventors: Tse-Wen CHANG, Jou-Han CHEN, Hsing-Mao CHU
  • Anti-inflammatory molecules with tissue-targeting functions
    Publication number: 20170152323
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: January 18, 2016
    Publication date: June 1, 2017
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen Chang, Jou-Han Chen, Hsing-Mao Chu
  • Multi-arm linker constructs for treating pathological blood clots
    Patent number: 9623118
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: April 18, 2017
    Inventors: Tse-Wen Chang, Hsing-Mao Chu, Chun-Yu Lin
  • MULTI-ARM LINKER FOR TREATING REJECTION REACTION IN TRANSPLANTATION
    Publication number: 20170056520
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 2, 2017
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU, Chun-Yu LIN, Wei-Ting TIAN
  • Pharmaceuticals in joint-linker configurations for treating pathological blood clots
    Publication number: 20170056518
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: July 18, 2016
    Publication date: March 2, 2017
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen Chang, Hsing-Mao Chu
  • Multi-arm linker constructs for treating pathological blood clots
    Publication number: 20170056517
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: July 18, 2016
    Publication date: March 2, 2017
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen Chang, Hsing-Mao Chu, Chun-Yu Lin
  • Fusion proteins for treating pathological blood clots
    Publication number: 20170056519
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: July 18, 2016
    Publication date: March 2, 2017
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen Chang, Hsing-Mao Chu, Wei-Ting Tian
  • FUSION PROTEIN FOR TREATING REJECTION REACTION IN TRANSPLANTATION
    Publication number: 20170056521
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 2, 2017
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU, Li-Yun DU
  • Peptide core-based multi-arm linkers and their applications
    Publication number: 20160339109
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU
  • Molecular constructs with targeting and effector moieties for treating central nervous system diseases
    Publication number: 20160339115
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU
  • Peptide core-based multi-arm linkers for treating infectious diseases
    Publication number: 20160339111
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU, Chien-Jen Lin, Chun-Yu Lin
  • Molecular constructs for treating central nervous system diseases
    Publication number: 20160340435
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU, Wei-Ting TIAN
  • Molecular constructs with targeting and effector moieties for treating infectious diseases
    Publication number: 20160339116
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU
  • Molecular constructs for treating infectious diseases
    Publication number: 20160340427
    Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 24, 2016
    Applicant: Immunwork Inc.
    Inventors: Tse-Wen CHANG, Hsing-Mao CHU, Jou-Han CHEN, Li-Yun DU