Patents by Inventor Hsiou-chi Liou

Hsiou-chi Liou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200345739
    Abstract: The present invention provides, inter alia, compounds capable of inhibiting NF-?B. Pharmaceutical compositions containing and methods of using the compounds are also provided herein.
    Type: Application
    Filed: April 27, 2020
    Publication date: November 5, 2020
    Inventors: Samedy Ouk, Hsiou-Chi Liou
  • Patent number: 10660894
    Abstract: The present invention provides, inter alia, compounds capable of inhibiting NF-?B. Pharmaceutical compositions containing and methods of using the compounds are also provided herein.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: May 26, 2020
    Assignee: ImmuneTarget, Inc.
    Inventors: Samedy Ouk, Hsiou-Chi Liou
  • Publication number: 20190314377
    Abstract: The disclosure relates to compounds and compositions that inhibit NF-?B and are useful in the treatment of hematological malignancies such as lymphoma and myeloma.
    Type: Application
    Filed: June 26, 2019
    Publication date: October 17, 2019
    Inventors: Johannes ZAKRZEWSKI, Hsiou-Chi LIOU, Samedy OUK
  • Publication number: 20190142836
    Abstract: The present invention provides, inter alia, compounds capable of inhibiting NF-?B. Pharmaceutical compositions containing and methods of using the compounds are also provided herein.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Inventors: Samedy Ouk, Hsiou-Chi Liou
  • Patent number: 10226464
    Abstract: The present invention provides, inter alia, compounds capable of inhibiting NF-?B. Pharmaceutical compositions containing and methods of using the compounds are also provided herein.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: March 12, 2019
    Assignee: ImmuneTarget, Inc.
    Inventors: Samedy Ouk, Hsiou-Chi Liou
  • Publication number: 20190000851
    Abstract: The present invention provides, inter alia, compounds capable of inhibiting NF-?B. Pharmaceutical compositions containing and methods of using the compounds are also provided herein. Also provided are methods and kits for treating cancer and solid tumors in a subject, as well as methods and kits for inducing cancer cell death and apoptosis of a cancer cell, all utilizing the NF-?B inhibitors described herein.
    Type: Application
    Filed: June 27, 2018
    Publication date: January 3, 2019
    Inventors: Samedy Ouk, Hsiou-Chi Liou
  • Patent number: 9873674
    Abstract: Compounds having a c-Rel inhibiting property according to the formula: (1) wherein R1 and R2 are each independently selected from hydrogen atom and hydrocarbon groups having at least one and up to thirty carbon atoms and optionally substituted with one or more heteroatoms selected from halogen, nitrogen, oxygen, and sulfur; R3 is selected from hydrocarbon groups having at least one and up to thirty carbon atoms and optionally substituted with one or more heteroatoms selected from halogen, nitrogen, oxygen, and sulfur; and X1, X2, and X3 are each independently selected from oxygen and sulfur atoms. Methods for treating diseases and conditions associated with c-Rel overexpression by administering compounds of Formula (1) or a pharmaceutical composition thereof to a subject afflicted with such a disease or condition are also described.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: January 23, 2018
    Assignee: CORNELL UNIVERSITY
    Inventors: Hsiou-Chi Liou, Mei-Ling Liou, Samedy Ouk
  • Publication number: 20170182051
    Abstract: The present invention provides, inter alia, compounds capable of inhibiting NF-?B. Pharmaceutical compositions containing and methods of using the compounds are also provided herein.
    Type: Application
    Filed: December 29, 2016
    Publication date: June 29, 2017
    Inventors: Samedy Ouk, Hsiou-Chi Liou
  • Publication number: 20150218109
    Abstract: Compounds having a c-Rel inhibiting property according to the formula: (1) wherein R1 and R2 are each independently selected from hydrogen atom and hydrocarbon groups having at least one and up to thirty carbon atoms and optionally substituted with one or more heteroatoms selected from halogen, nitrogen, oxygen, and sulfur; R3 is selected from hydrocarbon groups having at least one and up to thirty carbon atoms and optionally substituted with one or more heteroatoms selected from halogen, nitrogen, oxygen, and sulfur; and X1, X2, and X3 are each independently selected from oxygen and sulfur atoms. Methods for treating diseases and conditions associated with c-Rel overexpression by administering compounds of Formula (1) or a pharmaceutical composition thereof to a subject afflicted with such a disease or condition are also described.
    Type: Application
    Filed: September 19, 2013
    Publication date: August 6, 2015
    Inventors: Hsiou-Chi Liou, Mei-Ling Liou, Samedy Ouk
  • Publication number: 20100055116
    Abstract: The present invention relates to compositions and methods for targeting c-Rel. In particular, the present invention provides compositions and methods for treating cancers, inflammatory diseases, autoimmune diseases, and transplant rejection by inhibiting c-Rel activity and for regulating c-Rel for research and drug screening applications.
    Type: Application
    Filed: April 13, 2007
    Publication date: March 4, 2010
    Inventors: Hsiou-chi Liou, Wenzhi Tian, Shuhua Cheng, Constance Y. Hsia, Alex Owyang, Jason J. Hsu