Abstract: The present invention of a water and dust-proof control box structure mainly comprises a semi-box and a side cover. The semi-box having a panel board, a side board, an upper board and a lower board. The panel board having few holes and mounting spaces for inserting a turning knob and a sliding button. The control box can accommodate few IC boards. A back board is disposed at the back of the side cover, the side cover also having an upper board and a lower board. Few positioning blocks are disposed on the inner wall of the panel board, screw holes are disposed inside the positioning blocks for fixing a positioning board. A control knob and a switch are mounted on the positioning board, the control knob and the switch are capped by a water-proof cap or a water-proof pad. The water-proof cap or the water-proof pad are pressed against to the inner wall of the panel board by the turning knob and the switch. A water-proof piece is stuck on outside the panel board.