Patents by Inventor HSIU-WEN CHIEN

HSIU-WEN CHIEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190064547
    Abstract: A photochromic ophthalmic lens includes a body and a photochromic layer formed on each opposing surface of the body. Photochromic molecule-cyclodextrin inclusion compounds are dispersed in the photochromic layer. The photochromic molecule-cyclodextrin inclusion compounds includes cyclodextrins and photochromic molecules entrapped in a cavity of the cyclodextrins. A gradation of the self-darkening properties can be applied to the photochromic layers.
    Type: Application
    Filed: August 25, 2017
    Publication date: February 28, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190062624
    Abstract: A photochromic ophthalmic lens includes a body and photochromic molecule-cyclodextrin inclusion compounds dispersed in the body. The photochromic molecule-cyclodextrin inclusion compounds include cyclodextrins and photochromic molecules entrapped in a cavity of the cyclodextrins. Notwithstanding the hydrophobic nature of the photochromic molecules, the cyclodextrins, which contains cavities entrapping the photochromic molecules, are hydrophilic.
    Type: Application
    Filed: August 25, 2017
    Publication date: February 28, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190060508
    Abstract: A wound dressing which is removable with little or no adhesion to wounded tissue includes a wound contact layer. The wound contact layer comprises molecules which can be rapidly degraded by exposure to certain light, and non-sticking molecules. The photodegradable molecules includes at least one o-nitrobenzyl group.
    Type: Application
    Filed: December 6, 2017
    Publication date: February 28, 2019
    Inventor: Hsiu-Wen Chien
  • Publication number: 20190054215
    Abstract: An artificial corneal stroma comprises a hydrogel substrate supported by artificial stents. At least one surface comprises a plurality of nanosize structures. The hydrogel substrate is formed from an artificial corneal stroma material. The artificial corneal stroma material comprises a methacrylate-bonded hyaluronic acid, a collagen, and a photoinitiator.
    Type: Application
    Filed: August 31, 2017
    Publication date: February 21, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190056656
    Abstract: A method of making paper-based biosensor pattern comprises a sheet of paper provided as a substrate, and coating a hydrophobic photoresist on the substrate as a coating layer. At least a portion of the coating layer is exposed to make the hydrophobic photoresist in one or more exposed areas become a hydrophilic structure. The hydrophobic photoresist in one or more covered/unexposed area remains hydrophobic, thereby defining a pattern of the paper-based biosensor.
    Type: Application
    Filed: August 31, 2017
    Publication date: February 21, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190053890
    Abstract: An artificial intraocular lens device with light-induced zoom-in and zoom-out properties includes a lens, an inert lens frame surrounding the lens; and two inert supporting arms formed at the side edge of the lens frame. The lens is made from azobenzene gel, the deformation of the azobenzene gel by expansion or contraction respectively reverses on exposure to visible light and to ultraviolet light. The azobenzene gel is formed by heating an azobenzene gel precursor for polymerization, the azobenzene gel precursor being composed of monomer, initiator, crosslinker, and azobenzene.
    Type: Application
    Filed: November 29, 2017
    Publication date: February 21, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190056603
    Abstract: An ophthalmic lens producing an electrical current by means of two opposing electrode plates includes a matrix and a friction-based generator of electricity. The generator is in the matrix and includes a top electrode and a bottom electrode. The top electrode includes a polymer layer and a first metal layer stacked together. The bottom electrode includes a second metal layer facing the second metal layer. In an initial state, the second metal layer and the polymer layer are spaced apart from each other. In a contact state, the second metal layer and the polymer layer are configured to be in contact, through eye movement, to produce electricity.
    Type: Application
    Filed: December 20, 2017
    Publication date: February 21, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190054209
    Abstract: An artificial cornea stroma material comprises a methacrylated hyaluronic acid, a collagen, a photo-initiator, and a solvent. Ultraviolet radiation of the photo-initiator causes the methacrylated hyaluronic acid to polymerize to form a dense covalent bond cross-linking network gel structure. The gel structure has mechanical strength, and can keep in gel state for a long time. An artificial cornea stroma made from the artificial material, and an artificial cornea scaffold using the artificial cornea stroma are also provided.
    Type: Application
    Filed: August 18, 2017
    Publication date: February 21, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190039999
    Abstract: A cell seeding plate comprises a substrate and a photolysis layer formed on a surface of the substrate. The photolysis layer comprises a plurality of photolysis groups, and each of the plurality of photolysis groups has a chemical structural formula of R1 and R3 each represents alkane group, R2 comprises alkane group or olefin group, R5, R6 and R7 each represents hydrogen group or alkane group. Each of the plurality of photolysis groups is bonded to the surface by the amide group.
    Type: Application
    Filed: August 29, 2017
    Publication date: February 7, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190040380
    Abstract: A cell seeding substrate comprises a base comprising a rotary surface and a photolysis layer formed on the rotary surface of the base. The photolysis layer comprises a plurality of photolysis groups, and each of the plurality of photolysis groups has a chemical structural formula of R1 and R3 each represents alkane group, R2 comprises alkane group or olefin group, R5, R6 and R7 each represents hydrogen group or alkane group. Each of the plurality of photolysis groups is bonded to the rotary surface by the amide group.
    Type: Application
    Filed: August 31, 2017
    Publication date: February 7, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190040166
    Abstract: A liquid quality detecting device includes a spherical frame and a hydrogel ball received in the spherical frame. The hydrogel ball can be in an original state or an expanded state. In the original state, an inner diameter of the spherical frame is greater than an outer diameter of the hydrogel ball, thereby defining a channel allowing the liquid to pass. The hydrogel ball is made of hydrogel which is pH-sensitive. When the pH value of the liquid is greater than a preset pH range, the hydrogel ball expands, and the core layer expands to cause the outer diameter of the hydrogel ball to become equal to the inner diameter of the spherical frame, thereby causing the hydrogel ball to block the channel. When in contact with within-range liquid again, the hydrogel ball reverts to original size.
    Type: Application
    Filed: August 29, 2017
    Publication date: February 7, 2019
    Inventor: HSIU-WEN CHIEN
  • Patent number: 10196498
    Abstract: A method for making a colored film includes following steps of providing a mixture comprising a hydrophilic monomer, a functionalized vinylic monomer, a clay, a cross-linking agent, and an initiator; mixing a pigment and a solvent with the mixture to form a colored material; and placing the colored material into a mold, and exposing the colored material to ultraviolet radiation or heating the colored material, to cause the hydrophilic monomer, the functionalized vinylic monomer, the cross-linking agent, and the initiator in the colored material to undergo a polymerization reaction to form a cross-linking network, and the clay in the colored material to be dispersed in the cross-linking network, thereby forming the colored film. The disclosure also provides a colored film made by above method, a colored material making for the colored film, and an ophthalmic lens.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: February 5, 2019
    Assignee: ScienBiziP Consulting(Shenzhen)Co., Ltd.
    Inventor: Hsiu-Wen Chien
  • Publication number: 20190029952
    Abstract: For the manufacture of an ophthalmic lens, the ophthalmic lens includes a gel matrix, at least one first polyelectrolyte coating layer, at least one second polyelectrolyte coating layer, and drugs. The first polyelectrolyte coating layer is formed on the gel matrix. The second polyelectrolyte coating layer is formed on the first polyelectrolyte coating layer. The drugs are in place between the first polyelectrolyte coating layer and the second polyelectrolyte coating layer. The first polyelectrolyte coating layer and the second polyelectrolyte coating layer interact electrostatically. When intraocular pressure (TOP) rises, the electrostatic interaction between the first polyelectrolyte coating layer and the second polyelectrolyte coating layer is broken and the drugs are released.
    Type: Application
    Filed: October 13, 2017
    Publication date: January 31, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190031855
    Abstract: An optical lens material includes a cyclic block copolymer (CBC) and a reinforcing agent. The reinforcing agent is ZnO-TNTs. The ZnO-TNTs is TiO2 nanotubes incorporated with ZnO particles. The ZnO particles are adsorbed on the wall of the TiO2 nanotubes.
    Type: Application
    Filed: August 11, 2017
    Publication date: January 31, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190015022
    Abstract: A contact lens for detecting body glucose in tears includes a gel substrate, a plurality of platinum nanoparticles dispersed in the gel substrate, and a biosensor received in the gel substrate. The biosensor receives the glucose from tears as glucose oxidase and the glucose acid and hydrogen peroxide (H2O2) produced are decomposed to water and hydrogen peroxide. The platinum nanoparticles function as a catalytic agent to accelerate the degradation of the hydrogen peroxide into water and oxygen, avoiding or reducing hypoxia of the eye.
    Type: Application
    Filed: July 25, 2017
    Publication date: January 17, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190002643
    Abstract: An environmentally-sensitive material includes a sensitive layer and a base. The sensitive layer includes a mixed portion and a sensitive portion seamlessly connected to the mixed portion. The mixed portion is made of a mixture of a first polymer gel and a second polymer gel. The sensitive portion is made of the second polymer gel. The second polymer gel is a reversible gel which is able to revert to an original size and state as a changed environmental factor reverts to a starting state. A method for manufacturing the material is also provided.
    Type: Application
    Filed: August 22, 2017
    Publication date: January 3, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20190000359
    Abstract: An ophthalmic lens with glucose sensitive pad to indicate body glucose levels by changing color when in contact with tears from the eye includes a matrix, the matrix comprising a contact surface, the contact surface defining a micro-channel; and at least one glucose sensitive pad received in the micro-channel. A method for manufacturing an ophthalmic lens with glucose sensitive pad is also provided.
    Type: Application
    Filed: August 11, 2017
    Publication date: January 3, 2019
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20180368967
    Abstract: An artificial blood vessel includes a nanofiber base film and a nanofiber external film connected to the nanofiber base film. The nanofiber base film comprises a plurality of polymer nanofibers aligned according to a first single-direction aligning pattern. The nanofiber external film comprises a plurality of polymer nanofibers aligned according to a second aligning pattern that is perpendicularly different from the first aligning pattern.
    Type: Application
    Filed: June 30, 2017
    Publication date: December 27, 2018
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20180371644
    Abstract: A self-curling film includes a nanofiber base film and a nanofiber external film connected to the nanofiber base film. The nanofiber base film comprises a plurality of polymer nanofibers aligned according to a first single-direction aligning pattern. The nanofiber external film comprises a plurality of polymer nanofibers aligned according to a second aligning pattern that is the same as or different from the first aligning pattern. The polymer nanofibers of the nanofiber deformable film includes a temperature or UV-sensitive material that causes the nanofiber deformable film to shrink or expand when heated or exposed to ultraviolet radiation.
    Type: Application
    Filed: June 30, 2017
    Publication date: December 27, 2018
    Inventor: HSIU-WEN CHIEN
  • Publication number: 20180373061
    Abstract: An intraocular/intraocular lens which automatically adapts in radius to the corneal radius of the eye of a user includes a reversible gel layer. The reversible gel layer includes a contact surface. Radius of curvature of the contact surface changes when under a chemical reaction of the reversible gel layer induced by temperature, light, or acidity, the reaction being reversible.
    Type: Application
    Filed: June 30, 2017
    Publication date: December 27, 2018
    Inventor: HSIU-WEN CHIEN